Benefit-risk assessment of vitamin D supplementation [PDF]
Osteoporosis International, 2018 Summary: Current intake recommendations of 200 to 600IU vitamin D per day may be insufficient for important disease outcomes reduced by vitamin D. Introduction: This study assessed the benefit of higher-dose and higher achieved 25-hydroxyvitamin D levels
Bischoff-Ferrari, H. +5 more
core +6 more sources
Qualitative methods of benefit / risk assessment
Безопасность и риск фармакотерапии, 2022 In this article authors describe some existing methods of benefit / risk assessment.
A. P. Pereverzev +4 more
doaj +1 more source
Quantitative Benefit-Risk Assessment: State of the Practice Within Industry. [PDF]
Ther Innov Regul Sci, 2021 Abstract Background Benefit–risk assessments for medicinal products and devices have advanced significantly over the past decade. The purpose of this study was to characterize the extent to which the life sciences industry is utilizing quantitative benefit–risk assessment (qBRA) methods ...
Smith MY +4 more
europepmc +5 more sources
Food & Nutrition Research, 2018 Background: Nationally representative information on food consumption data is essential to evaluate dietary habits, inform policy-making and nutritional guidelines, as well as forming a basis for risk assessment and identification of risk groups ...
Lotta Moraeus +5 more
doaj +1 more source
Recommendations for benefit-risk assessment methodologies and visual representations. [PDF]
, 2015 Purpose The purpose of this study is to draw on the practical experience from the PROTECT BR case studies and make recommendations regarding the application of a number of methodologies and visual representations for benefit–risk assessment.
Ashby, D +15 more
core +2 more sources
Relationship of Hearing Impairment in Patients with Lamivudine Therapy: A Systematic Review and Meta-analysis [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Lifelong Antiretroviral Therapy (ARVT) in patients with Human Immunodeficiency Virus (HIV) infection damages cochlea. Hearing Loss (HL) has been reported with lamivudine therapy in both HIV and/or Hepatitis B Virus (HBV) infections.
Mahesh Namdeo Belhekar, Kalpesh K Joshi
doaj +1 more source
Multicriteria benefit–risk assessment using network meta-analysis [PDF]
Journal of Clinical Epidemiology, 2012 To enable multicriteria benefit-risk (BR) assessment of any number of alternative treatments using all available evidence from a network of clinical trials.We design a general method for multicriteria decision aiding with criteria measurements from Mixed Treatment Comparison (MTC) analyses.
van Valkenhoef, Gert +5 more
openaire +2 more sources
Structured frameworks to increase the transparency of the assessment of benefits and risks of medicines: current status and possible future directions [PDF]
, 2015 Structured frameworks for benefit-risk analysis in drug licensing decisions are being implemented across a number of regulatory agencies worldwide.
Ashby, D +17 more
core +9 more sources
Bronchial thermoplasty : a new therapeutic option for the treatment of severe, uncontrolled asthma in adults [PDF]
, 2014 Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit for long-term asthma control outweighs the short-term risk of deterioration and hospitalisation in the days following the treatment.
Alagha, Khuder +10 more
core +5 more sources
Uncertainty of net present value calculations and the impact on applying integrated maintenance approaches to the UK rail industry [PDF]
, 2015 The Public performance indicator (PPI) is an important Key Performance Indicator for Network Rail and monitored carefully by the organisation and their external stakeholders.
Andrew, Starr +3 more
core +1 more source