Results 61 to 70 of about 151,271 (335)

A MICROBIAL CONTAMINATION OF PROSTATIC TISSUE IN BENIGN PROSTATIC HYPERPLASIA AND PROSTATE CANCER

open access: yesВестник урологии, 2013
Bacteriological results of prostatic tissue in benign prostatic hyperplasia and prostate cancer are shown in this article. A use of extended amount of media for bacterial isolation allows a wide spectrum of nonclostridial anaerobic (Bacteroides sp ...
Y. L. Naboka   +2 more
doaj   +1 more source

Computer simulations suggest that prostate enlargement due to benign prostatic hyperplasia mechanically impedes prostate cancer growth

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Benign prostatic hyperplasia (BPH) is a common disease in aging men that causes the prostate to enlarge progressively. Men with larger prostates tend to harbor prostatic tumors with more favorable features.
G. Lorenzo   +4 more
semanticscholar   +1 more source

Combination of Autoantibody Signature with PSA Level Enables a Highly Accurate Blood-Based Differentiation of Prostate Cancer Patients from Patients with Benign Prostatic Hyperplasia. [PDF]

open access: yesPLoS ONE, 2015
Although an increased level of the prostate-specific antigen can be an indication for prostate cancer, other reasons often lead to a high rate of false positive results.
Petra Leidinger   +11 more
doaj   +1 more source

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Successful treatment of complicated benign prostatic hyperplasia in a diabetic patient with water vapor thermal therapy and urethral stenting

open access: yesUrology Case Reports, 2019
Water Vapor Thermal Therapy is a novel, office-based procedure which has gained traction as first line therapy in specific therapeutic cases of benign prostatic hyperplasia.
Tej J. Desai, Jared J. Wallen
doaj   +1 more source

What is a disease? What is the disease clinical benign prostatic hyperplasia (BPH)?

open access: yesWorld journal of urology, 2019
IntroductionThough clinical benign prostatic hyperplasia (BPH) is a common disease worldwide, there is still much confusion in the literature and the many clinical guidelines as to its definition.
K. Foo
semanticscholar   +1 more source

Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate. [PDF]

open access: yes, 1993
associated with aging. Thus, the question arises whether or not a correlation exists between the well known prostatic androgen and estrogen accumulation and aging.
Krieg, Michael, Nass, Ralf, Tunn, Sabine
core   +1 more source

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

open access: yesFood Frontiers, EarlyView.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli   +8 more
wiley   +1 more source

Correlation of prostate volume with 'International Prostate Symptom Score' and 'Benign Prostatic Hyperplasia-Impact Index' in benign prostatic hyperplasia

open access: yesJournal of Society of Surgeons of Nepal, 2016
Introduction: Benign prostatic Hyperplasia is a common disorder and cause of morbidity in the ageing men. The evaluation symptoms and the bother associated with it are important for management. International Prostate Symptom Score (IPSS), Quality of life
D Gnyawali, U Sharma
doaj   +1 more source

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