Results 91 to 100 of about 33,916 (231)

(E)-2-(4-Nitrobenzylideneamino)benzamide [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2009
The title compound, C(14)H(11)N(3)O(3), adopts an E conformation, with a dihedral angle of 41.8 (1) ° between the mean planes of the two benzene rings. One of the amino H atoms forms an intra-molecular hydrogen bond with the amide N atom, while the other H atom forms an inter-molecular hydrogen bond with the carbonyl O atom of an adjacent mol-ecule ...
Shu-Liang Wang   +3 more
openaire   +3 more sources

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

3-Fluoro-N-(3-fluorobenzoyl)-N-(2-pyridyl)benzamide [PDF]

open access: yes, 2009
The title compound, C19H12F2N2O2, a 2:1 product of the reaction of 3-fluorobenzoylchloride and 2-aminopyridine crystallizes with a disordered 3-fluorobenzene ring adopting two conformations [ratio of occupancies 0.959 (4):0.041 (4)].
Donnelly, Katie, Gallagher, John F.
core   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

open access: yesSmall, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi   +14 more
wiley   +1 more source

The Mode of Protonation of Amides [PDF]

open access: yes, 1958
The relative basicities of oxygen versus nitrogen in amides is a problem which has not been satisfactorily resolved. However, it might be anticipated from considerations of resonance and structural parameters that in strongly acidic solutions the proton ...
Fraenkel, Gideon, Niemann, Carl
core   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros   +5 more
wiley   +1 more source

Crystal structures of 3-fluoro-N-[2-(trifluoromethyl)phenyl]benzamide, 3-bromo-N-[2-(trifluoromethyl)phenyl]benzamide and 3-iodo-N-[2-(trifluoromethyl)phenyl]benzamide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
In the title compounds, C14H9F4NO, (I), C14H9BrF3NO, (II), and C14H9F3INO, (III), the two benzene rings are inclined to one another by 43.94 (8)° in molecule A and 55.66 (7)° in molecule B of compound (I), which crystallizes with two independent ...
P. A. Suchetan   +3 more
doaj   +1 more source

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis [PDF]

open access: yes, 2019
The antitumor agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (1) is a potent inhibitor of GSTP1-1, a glutathione S-transferase capable of inhibiting apoptosis by binding to JNK1 and TRAF2.
Caccuri, A. M.   +9 more
core   +2 more sources

N-[Morpholino(phenyl)methyl]benzamide [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2009
The title compound, C(18)H(20)N(2)O(2), crystallizes with two mol-ecules in the asymmetric unit. The morpholine rings of both mol-ecules adopt chair conformations. The crystal structure is stabilized by inter-molecular N-H⋯O hydrogen bonds. One phenyl ring is disordered over two orientations in a 0.665 (5):0.335 (5) ratio.
Muruganandam, L.   +4 more
openaire   +3 more sources

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim   +10 more
wiley   +1 more source

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