Results 181 to 190 of about 4,384 (210)

2‐Benzazepines. 7. Synthesis of pyrimido[5,4‐d][2]benzazepines

Journal of Heterocyclic Chemistry, 1983
AbstractTwo novel syntheses of pyrimido[5,4‐d][2]benzazepines are described. The first synthesis started with 3‐phenylphthalide which in three steps was converted to a functionalized pyrimidine which was cyclized to give the 2‐benzazepine ring system.
James V. Earley, R. Ian Fryer, Norman W. Gilman   +2 more
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Fused [1]Benzazepines. Pentacyclic [1]Benzazepines by Reaction of 1H-[1]Benzazepine-2,5(3H,4H)-dione with Aldehydes

HETEROCYCLES, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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ChemInform Abstract: 2‐Benzazepines. Part 9. Synthesis and Chemistry of 3H‐2‐Benzazepine and Pyrimido(4,5‐d)(2)benzazepine Derivatives.

ChemInform, 1987
AbstractThe benzazepines (II), prepared from the acetylenes (I), are transformed into the isomeric esters (VI) and (VII) by consecutive bromination, dehydrobromination, and palladium‐catalyzed alkoxycarbonylation.
E. J. TRYBULSKI, R. I. FRYER, E. REEDER, S. VITONE, L. TODARO   +4 more
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Electrochemical oxidation of 2,5-dihydro-1h-1-benzazepines : Synthesis of 5H-1-benzazepines

Tetrahedron, 1995
Abstract Formation of 5H-1-benzazepines was observed after electrochemical oxidation of the title compounds in a flow cell at a graphite felt anode and in acetic buffer. In basic medium, coupling reaction also occurs leading to [2,5-dihydro-1H-1-benzazepin-1-yl]-5H-1-benzazepines. Oxidation mechanisms are discussed.
B. Kharraz, P. Uriac, L. Toupet, J.P. Hurvois, C. Moinet, A. Tallec   +5 more
openaire   +1 more source

Preparation d'hexahydroisoquinoleino [3,2-b] benzazepines-3; transposition en hexahydroisoquinoleino [2,1-b] benzazepines-2

Tetrahedron, 1983
Abstract Pictet-Spengler cyclisation of threo 1-hydroxy-2-(3',4'-methylenedioxybenzyl)-7, 8-dimethoxy-2,3,4,5-tetrahydro-1H 3-benzazepine 2b gives a mixture of diastereoisomers of 14-hydroxy-2,3-dimethoxy-10,11-methylenedioxy-5,6,8,13,13a,14-hexahydroisoquino [3,2-b] 3-benzazepine 3a and 3b .
A. Graftieaux, J. Likforman, J. Gardent
openaire   +1 more source

ChemInform Abstract: 2‐BENZAZEPINES. 7. SYNTHESIS OF PYRIMIDO(5,4‐D)(2)BENZAZEPINES

Chemischer Informationsdienst, 1984
AbstractDas 3‐Phenyl‐phthalid (I) wird mit dem Anion des Acetonitrils zu Hydroxyisobenzofuran (II) umgesetzt.
J. V. EARLEY, R. I. FRYER, N. W. GILMAN
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Regioselective alkylation reactions of 2,4-diphenyl-3H-1-benzazepine give either 3-alkyl-3H-1-benzazepines or 1-alkyl-1H-1-benzazepines

Tetrahedron Letters, 2014
2,4-Diphenyl-3H-1-benzazepine is deprotonated with either LDA or KHMDS. The resulting anion is alkylated with alkyl halides or MeOTs, giving either products of alkylation at C3, or at N, or a mixture of both. The regioselectivity depends on the base, presence of the complexing agent HMPA, and the leaving group of the alkylating agent.
Allen Ko, Aaron Lam, Jeffrey Li, Edyta M. Greer, David J. Szalda, Sasan Karimi, Gopal Subramaniam, Keith Ramig   +7 more
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Synthesis of Dihydro-1-benzazepines

HETEROCYCLES, 2013
A variety of dihydro-1-benzazepines (X) is prepared via a Claisen rearrangement of allyl phenyl ether (III) and a ring-closing metathesis of dienes (IX) as key steps.
Meng-Yang Chang, Chieh-Kai Chan, Shin-Ying Lin   +2 more
openaire   +1 more source

1-Benzazepines. The Synthesis and Reactivity of 2-Chloro-1,5-Dimethyl-1h-1-Benzazepines

Australian Journal of Chemistry, 1986
Treatment of laevulinic acid with N- methylaniline yields 1,5-dimethyl- 1H-1-benzazepin-2(3H)-one and 5-methyl-5-[4-( methylamino )phenyl]-1- phenylpyrrolidin-2-one. The structure of the latter is confirmed by a single-crystal X-ray study. The yield of benzazepinone is increased if either m- methoxy-N-methylaniline or m-methyl-N- methylaniline is ...
JH Bowie, RN Hayes, S Mitkas, RH Prager, MJ Raftery, BW Skelton, MB Stringer, AH White   +7 more
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Synthesis of tetrahydro-3-benzazepines

Tetrahedron, 2012
Abstract A synthetic route toward tetrahdro-3-benzazepines 1a – f starting with 2a and 2b in modest total yield is described. The facile route was carried by Henry reaction of aldehydes 3a – e with nitroalkanes and NH 4 OAc at reflux, reduction of the resulting nitroalkenes 4a – h with LAH at rt followed by protection with K 2 CO 3 and ...
Meng-Yang Chang, Chieh-Kai Chan, Shin-Ying Lin, Ru-Ting Hsu   +3 more
openaire   +1 more source