Results 191 to 200 of about 4,384 (210)

1,5-Ethano-2,3,4,5-tetrahydro-1H-3-benzazepines

Journal of Medicinal Chemistry, 1975
1,5-Ethano-2,3,4,5-tetrahydro-1H-3-benzazepine, from the LiA1H4 reduction of 2-benzyloxy-1,5-ethano-4-oxo-2,3,4,5-tetrahydro-1H-3-benzazepine, was converted to N-alkyl, aralkyl, cycloalkyl, and alkenyl derivatives which were inactive as morphine type analgetics in mice.
L A, Walter, W K, Chang
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2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents

Journal of Medicinal Chemistry, 1983
A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepin-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different than that of diazepam. They are more potent than diazepam in the anti-pentylenetetrazole test and in
E J, Trybulski, L E, Benjamin, J V, Earley, R I, Fryer, N W, Gilman, E, Reeder, A, Walser, A B, Davidson, W D, Horst, J, Sepinwall   +9 more
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Synthesis and Biological Evaluation of Benzazepine Oxazolidinone Antibacterials.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Paul D, Johnson, Paul A, Aristoff, Gary E, Zurenko, Ronda D, Schaadt, Betty H, Yagi, Charles W, Ford, Judith C, Hamel, Douglas, Stapert, Judy K, Moerman   +8 more
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ChemInform Abstract: Regioselective Alkylation Reactions of 2,4‐Diphenyl‐3H‐1‐benzazepine Give Either 3‐Alkyl‐3H‐1‐benzazepines or 1‐Alkyl‐1H‐1‐benzazepines.

ChemInform, 2014
AbstractDeprotonation of benzazepine (I) followed by reaction with alkyl halides or tosylates give either products of alkylation at C3 or at the nitrogen as well as mixtures of both types of products.
Allen Ko, Aaron Lam, Jeffrey Li, Edyta M. Greer, David J. Szalda, Sasan Karimi, Gopal Subramaniam, Keith Ramig   +7 more
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ChemInform Abstract: Electrochemical Oxidation of 2,5‐Dihydro‐1H‐1‐benzazepines: Synthesis of 5H‐1‐Benzazepines.

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
B. KHARRAZ, P. URIAC, L. TOUPET, J. P. HURVOIS, C. MOINET, A. TALLEC   +5 more
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Synthesis of Benzazepine Analogues of Noscapine

Helvetica Chimica Acta, 1994
AbstractThe synthesis of benzazepine analogues of the opium alkaloid noscapine (1) is described. The benzazepines 2 and 3 were prepared starting from nornarceine ethyl ester (4; readily available from 1) in several steps. X‐Ray analysis of compound 2 revealed that it is not a diastereosisomer mixture but a racemate of the threo‐form and thus has the ...
Helmut Schmidhammer, Eva Scherb‐Bukowiecki, Thomas A. Mayer, Peter Schönholzer   +3 more
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The Synthesis of Hydroxytrifluoromethyl 3H-Benzazepines

Synthetic Communications, 1980
Abstract Recent reports have described the dopamine agonist properties of several 7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydrolH-3-benzazepines1. In an attempt to further explore the substitution pattern needed for activity, we required a method for introducing a trifluoromethyl group into the fused aromatic ring and a method for O-demethylation without ...
Dimitri Gaitanopoulos, Martin Brenner
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Conversion of tetrahydroisoquinolinium salts into benzazepines

The Journal of Organic Chemistry, 1984
Conversion de methyl-2 nitro-4' benzyl-2 tetrahydro-1,2,3,4 isoquinoleiniums en methyl-3 nitro-4' phenyl-2 tetrahydro-2,3,4,5 benzoazepines-3 par action du t-butanolate de potassium dans le t-butanol.
Stephen Smith, Veradaraj Elango, Maurice Shamma   +2 more
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A New Synthesis of 2-Benzazepines

Synthesis, 2002
AlCl 3 -mediated intramolecular cyclization of N,N-bis(1H-1,2,3-benzotriazol-1-ylmethyl)-3-phenyl-1-propanamine (5) gave 2-benzotriazolylmethyl-2,3,4,5-tetrahydro-1H-2-benzazepine (6). Subsequent nuclcophilic substitution of the benzotriazolyl group in 6 with Grignard reagents, triethyl phosphite and sodium borohydride afforded 2,3,4,5-tetrahydro-1H-2 ...
Alan R. Katritzky, Rexiat Maimait, Yong-Jiang Xu, Rena G. Akhmedova   +3 more
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ChemInform Abstract: 1‐Benzazepines. The Synthesis and Reactivity of 2‐Chloro‐1,5‐dimethyl‐1H‐1‐benzazepines.

Chemischer Informationsdienst, 1986
AbstractTreatment of laevulinic acid (I) with the anilines (II) and its salts (III) yields the benzazepinones (IV).
J. H. BOWIE, R. N. HAYES, S. MITKAS, R. H. PRAGER, M. J. RAFTERY, B. W. SKELTON, M. B. STRINGER, A. H. WHITE   +7 more
openaire   +1 more source