Results 211 to 220 of about 6,469 (247)

Derivatives of 2-benzazepine-1,3-dione

Chemistry of Heterocyclic Compounds, 1984
AbstractDie aus dem S‐Opianylidenrhodanin (I) durch alkalische Ilydrolyse hergestellte Thiobrenztraubensäure (II) wird über das Säurechlorid (III) mit 1‐Aminoadamantan (IV) bzw. Thiosemicarbazid (VI) in das Dihydrobenzazepindion (V) bzw. (VII) ′umgewandelt.
G. N. Sementsiv, N. M. Turkevich
openaire   +3 more sources

Biocatalytic Access to Chiral Benzazepines Using Imine Reductases

ACS Catalysis, 2023
Anshul Rajput, T. Manna, A. Mondal, Arijit De, Jhilik Mondal, S. Husain   +5 more
semanticscholar   +1 more source

1-, 2-, and 3-Benzazepines

1974
Publisher Summary This chapter discusses 1-, 2-, and 3-Benzazepines. Ring closure with the formation of a carbon-nitrogen bond, of the types A-E shown in the chapter, has been used to synthesize derivatives of 1-, 2-, and 3-benzazepines, with aminocarboxylic acids, amino halides, dihalides, dinitriles, dicarboxylic acids, and carboxylic acid diamides
openaire   +2 more sources

Chemistry and biological activity of new 3-benzazepines

International Journal of Antimicrobial Agents, 2000
This review summarizes our experiments investigating structure-activity relationships of 3-benzazepines. Three 7, 8-dihydroxy-3-benzazepines [7-9] were cytotoxic to human promyelotic leukaemia HL-60 cells. Compound [9] showed the highest cytotoxicity and the activity was twice as high as that of dopamine (DA, [11]).
Noboru Motohashi, Setsuo Saito, Masami Kawase   +2 more
openaire   +3 more sources

ChemInform Abstract: 2‐BENZAZEPINES. 5. SYNTHESIS OF PYRIMIDO(5,4‐D)(2)BENZAZEPINES AND THEIR EVALUATION AS ANXIOLYTIC AGENTS

Chemischer Informationsdienst, 1984
AbstractDie Pyrimidobenzazepine (IV) und ähnliche Verbindungen werden dargestellt.
Norman W. Gilman, Eugene J. Trybulski, J. Sepinwall, Earl Reeder, L. E. Sen. Benjamin, Armin Walser, A. B. Davidson, W. D. Horst, R. A. O'brien, Rodney Ian Fryer, James Valentine Earley, W. Dairman   +11 more
openaire   +2 more sources

ChemInform Abstract: Cyclopropenes for the Synthesis of Cyclopropane‐Fused Dihydroquinolines and Benzazepines.

ChemInform, 2015
AbstractA novel Povarov‐type three‐component reaction of cyclopropenes, anilines, and aromatic aldehydes is efficiently catalyzed by TfOH leading to desired cyclopropane‐fused dihydroquinolines (IV) and (VIII), which are converted into N‐triflated benzazepines (VI) and (IX), resp., via a ring opening/isomerization reaction.
Hui-Xin Luo, Hui-Xin Luo, Xiao-Ping Cao, Xin-Shan Ye, Youhong Niu   +4 more
openaire   +3 more sources

ChemInform Abstract: Microwave Assisted Synthesis of 3‐Benzazepine‐2‐ones as Building Blocks for 2,3‐Disubstituted Tetrahydro‐3‐benzazepines.

ChemInform, 2012
AbstractThe compounds (VI) are investigated for their affinities toward σ1 and σ2 receptors in competitive receptor binding studies.
Roland Fröhlich, Syed Masood Husain, Bernhard Wünsch, Dirk Schepmann, Soumya Sarkar   +4 more
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Preparation d'hexahydroisoquinoleino [3,2-b] benzazepines-3; transposition en hexahydroisoquinoleino [2,1-b] benzazepines-2

Tetrahedron, 1983
Abstract Pictet-Spengler cyclisation of threo 1-hydroxy-2-(3',4'-methylenedioxybenzyl)-7, 8-dimethoxy-2,3,4,5-tetrahydro-1H 3-benzazepine 2b gives a mixture of diastereoisomers of 14-hydroxy-2,3-dimethoxy-10,11-methylenedioxy-5,6,8,13,13a,14-hexahydroisoquino [3,2-b] 3-benzazepine 3a and 3b .
A. Graftieaux, J. Likforman, J. Gardent
openaire   +2 more sources

2-Benzazepines. 8. Zerovalent nickel mediated biaryl synthesis of an anxiolytic pyrimido[5,4-d][2]benzazepine

The Journal of Organic Chemistry, 1984
Synthese du compose du titre par copulation de chloro-4 methyl-5 pyrimidine et de dichloro-2',5 iodo-2 benzophenone en presence de Ni(COD) 2 suivie de bromation et cyclisation avec l'ammoniac. La reaction en presence de Ni(COD) 2 conduit egalement au dimethyl-5,5' bipyrimidinyle-4,4', a la chloro-2 fluorene et au bis-[chloro-2 benzoyl]-2,2' dichloro ...
David L. Coffen, Julia B. Cheung, Beatrice Schaer, Fred T. Bizzarro   +3 more
openaire   +2 more sources

ChemInform Abstract: Synthesis of Phenethylenamides and Their Radical Cyclization to 3‐Benzazepines.

ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Luis Castedo, María Magdalena Cid, Domingo Domínguez, Ezequiel M. Vázquez-López   +3 more
openaire   +3 more sources