Results 211 to 220 of about 6,457 (248)

Regioselective alkylation reactions of 2,4-diphenyl-3H-1-benzazepine give either 3-alkyl-3H-1-benzazepines or 1-alkyl-1H-1-benzazepines

Tetrahedron Letters, 2014
AbstractDeprotonation of benzazepine (I) followed by reaction with alkyl halides or tosylates give either products of alkylation at C3 or at the nitrogen as well as mixtures of both types of products.
Allen Ko, Gopal Subramaniam, David J. Szalda, Aaron Lam, Jeffrey Li, Sasan Karimi, Edyta M. Greer, Keith Ramig   +7 more
openaire   +3 more sources

Synthesis of Quinoline-Fused 1-Benzazepines through a Mannich-Type Reaction of a C,N-Bisnucleophile Generated from 2-Aminobenzaldehyde and 2-Methylindole.

Organic Letters, 2016
Various quinoline-fused 1-benzazepine derivatives were synthesized using the C,N-1,6-bisnucleophile generated in situ from o-aminobenzaldehyde and 2-methylindole through a Mannich-type reaction.
Lijun Min, B. Pan, Yanlong Gu
semanticscholar   +1 more source

Benzazepines and Their Group 15 Analogues

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

ChemInform Abstract: An Efficient Approach for the Construction of Benzazepine and Benzoxepine Derivatives.

ChemInform, 2012
AbstractThe reaction of 2‐(2‐ethynylphenyl)‐1‐tosylaziridines with various sulfonyl azides affords the corresponding benzazepines with different substitution on the aromatic ring and tolerates various sulfonyl groups [cf.
Shaoyu Li, Jie Wu, Jie Wu, Shaowu Zou
openaire   +4 more sources

Solvent and catalyst free ring expansion of indoles: a simple synthesis of highly functionalized benzazepines.

Organic and biomolecular chemistry, 2018
Highly functionalized benzazepines have been synthesized by using various substituted indoles and dialkylacetylene dicarboxylates under thermal and open air conditions.
M. Bakthadoss, Polu Vijay Kumar, Tadiparthi Thirupathi Reddy, D. Sharada   +3 more
semanticscholar   +1 more source

Synthesis Of 1-Benzazepines as Precursors of 1-Benzazepinediones

Synthetic Communications, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Pessoa Mahana, H, Valderrama, JA
openaire   +4 more sources

Stereochemistry of N-Benzoyl-5-substituted-1-benzazepines Revisited: Synthesis of the Conformationally Biased Derivatives and Revision of the Reported Structure.

Journal of Organic Chemistry, 2016
The syn (aR*,5R*) and anti (aS*,5R*) diastereomers of N-benzoyl-C5-substituted-1-benzazepines originating in the chiralities at C5 and the Ar-N(C═O) axis were first stereoselectively synthesized by biasing the conformation with a substituent at C6 and C9,
H. Tabata, T. Yoneda, Tomohiko Tasaka, S. Ito, T. Oshitari, Hideyo Takahashi, H. Natsugari   +6 more
semanticscholar   +1 more source

Derivatives of 2-benzazepine-1,3-dione

Chemistry of Heterocyclic Compounds, 1984
AbstractDie aus dem S‐Opianylidenrhodanin (I) durch alkalische Ilydrolyse hergestellte Thiobrenztraubensäure (II) wird über das Säurechlorid (III) mit 1‐Aminoadamantan (IV) bzw. Thiosemicarbazid (VI) in das Dihydrobenzazepindion (V) bzw. (VII) ′umgewandelt.
G. N. Sementsiv, N. M. Turkevich
openaire   +3 more sources

Synthesis of 3‐Benzazepines by Metal‐Free Oxidative C–H Bond Functionalization–Ring Expansion Tandem Reaction

, 2016
A metal-free synthesis of biologically important benzazepines is achieved through a single synthetic operation involving an oxidative C–H bond functionalization and ring expansion with diazomethanes as key reagent.
Andrea Gini, J. Bamberger, Javier Luis‐Barrera, Mercedes Zurro, R. Mas‐Ballesté, J. Alemán, O. Mancheño   +6 more
semanticscholar   +1 more source

Interplay of Nitrogen-Atom Inversion and Conformational Inversion in Enantiomerization of 1H-1-Benzazepines.

Journal of Organic Chemistry, 2016
A series of 2,4-disubstituted 1H-1-benzazepines, 2a-d, 4, and 6, were studied, varying both the substituents at C2 and C4 and at the nitrogen atom. The conformational inversion (ring-flip) and nitrogen-atom inversion (N-inversion) energetics were studied
K. Ramig, G. Subramaniam, S. Karimi, D. Szalda, Allen Ko, Aaron Lam, Jeffrey Li, Ani Coaderaj, Leyla Cavdar, L. Bogdan, Kitae Kwon, Edyta M. Greer   +11 more
semanticscholar   +1 more source