Results 221 to 230 of about 6,457 (248)
Some of the next articles are maybe not open access.
1974
Publisher Summary This chapter discusses 1-, 2-, and 3-Benzazepines. Ring closure with the formation of a carbon-nitrogen bond, of the types A-E shown in the chapter, has been used to synthesize derivatives of 1-, 2-, and 3-benzazepines, with aminocarboxylic acids, amino halides, dihalides, dinitriles, dicarboxylic acids, and carboxylic acid diamides
openaire +2 more sources
Publisher Summary This chapter discusses 1-, 2-, and 3-Benzazepines. Ring closure with the formation of a carbon-nitrogen bond, of the types A-E shown in the chapter, has been used to synthesize derivatives of 1-, 2-, and 3-benzazepines, with aminocarboxylic acids, amino halides, dihalides, dinitriles, dicarboxylic acids, and carboxylic acid diamides
openaire +2 more sources
Chemistry and biological activity of new 3-benzazepines
International Journal of Antimicrobial Agents, 2000This review summarizes our experiments investigating structure-activity relationships of 3-benzazepines. Three 7, 8-dihydroxy-3-benzazepines [7-9] were cytotoxic to human promyelotic leukaemia HL-60 cells. Compound [9] showed the highest cytotoxicity and the activity was twice as high as that of dopamine (DA, [11]).
Noboru Motohashi +2 more
openaire +3 more sources
Biocatalytic Access to Chiral Benzazepines Using Imine Reductases
ACS Catalysis, 2023Anshul Rajput +5 more
semanticscholar +1 more source
Chemischer Informationsdienst, 1984
AbstractDie Pyrimidobenzazepine (IV) und ähnliche Verbindungen werden dargestellt.
Norman W. Gilman +11 more
openaire +2 more sources
AbstractDie Pyrimidobenzazepine (IV) und ähnliche Verbindungen werden dargestellt.
Norman W. Gilman +11 more
openaire +2 more sources
ChemInform, 2015
AbstractA novel Povarov‐type three‐component reaction of cyclopropenes, anilines, and aromatic aldehydes is efficiently catalyzed by TfOH leading to desired cyclopropane‐fused dihydroquinolines (IV) and (VIII), which are converted into N‐triflated benzazepines (VI) and (IX), resp., via a ring opening/isomerization reaction.
Hui-Xin Luo +4 more
openaire +3 more sources
AbstractA novel Povarov‐type three‐component reaction of cyclopropenes, anilines, and aromatic aldehydes is efficiently catalyzed by TfOH leading to desired cyclopropane‐fused dihydroquinolines (IV) and (VIII), which are converted into N‐triflated benzazepines (VI) and (IX), resp., via a ring opening/isomerization reaction.
Hui-Xin Luo +4 more
openaire +3 more sources
Chemical Communications, 2017
A novel and facile synthetic strategy for the construction of 1-benzazepines has been developed via copper-catalyzed oxidative C(sp3)-H/C(sp2)-H cross-coupling directly from two inert C-H bonds. This transformation represents an atom- and step-economical
Rui Wang +4 more
semanticscholar +1 more source
A novel and facile synthetic strategy for the construction of 1-benzazepines has been developed via copper-catalyzed oxidative C(sp3)-H/C(sp2)-H cross-coupling directly from two inert C-H bonds. This transformation represents an atom- and step-economical
Rui Wang +4 more
semanticscholar +1 more source
ChemInform, 2012
AbstractThe compounds (VI) are investigated for their affinities toward σ1 and σ2 receptors in competitive receptor binding studies.
Roland Fröhlich +4 more
openaire +3 more sources
AbstractThe compounds (VI) are investigated for their affinities toward σ1 and σ2 receptors in competitive receptor binding studies.
Roland Fröhlich +4 more
openaire +3 more sources
Tetrahedron, 1983
Abstract Pictet-Spengler cyclisation of threo 1-hydroxy-2-(3',4'-methylenedioxybenzyl)-7, 8-dimethoxy-2,3,4,5-tetrahydro-1H 3-benzazepine 2b gives a mixture of diastereoisomers of 14-hydroxy-2,3-dimethoxy-10,11-methylenedioxy-5,6,8,13,13a,14-hexahydroisoquino [3,2-b] 3-benzazepine 3a and 3b .
A. Graftieaux, J. Likforman, J. Gardent
openaire +2 more sources
Abstract Pictet-Spengler cyclisation of threo 1-hydroxy-2-(3',4'-methylenedioxybenzyl)-7, 8-dimethoxy-2,3,4,5-tetrahydro-1H 3-benzazepine 2b gives a mixture of diastereoisomers of 14-hydroxy-2,3-dimethoxy-10,11-methylenedioxy-5,6,8,13,13a,14-hexahydroisoquino [3,2-b] 3-benzazepine 3a and 3b .
A. Graftieaux, J. Likforman, J. Gardent
openaire +2 more sources
Acta Crystallographica Section C Structural Chemistry, 2016
Tetrahydro-1-benzazepines have been described as potential antiparasitic drugs for the treatment of chagas disease and leishmaniasis, two of the most important so-called `forgotten tropical diseases' affecting South and Central America, caused by ...
M. Macías +6 more
semanticscholar +1 more source
Tetrahydro-1-benzazepines have been described as potential antiparasitic drugs for the treatment of chagas disease and leishmaniasis, two of the most important so-called `forgotten tropical diseases' affecting South and Central America, caused by ...
M. Macías +6 more
semanticscholar +1 more source
The Journal of Organic Chemistry, 1984
Synthese du compose du titre par copulation de chloro-4 methyl-5 pyrimidine et de dichloro-2',5 iodo-2 benzophenone en presence de Ni(COD) 2 suivie de bromation et cyclisation avec l'ammoniac. La reaction en presence de Ni(COD) 2 conduit egalement au dimethyl-5,5' bipyrimidinyle-4,4', a la chloro-2 fluorene et au bis-[chloro-2 benzoyl]-2,2' dichloro ...
David L. Coffen +3 more
openaire +2 more sources
Synthese du compose du titre par copulation de chloro-4 methyl-5 pyrimidine et de dichloro-2',5 iodo-2 benzophenone en presence de Ni(COD) 2 suivie de bromation et cyclisation avec l'ammoniac. La reaction en presence de Ni(COD) 2 conduit egalement au dimethyl-5,5' bipyrimidinyle-4,4', a la chloro-2 fluorene et au bis-[chloro-2 benzoyl]-2,2' dichloro ...
David L. Coffen +3 more
openaire +2 more sources