Results 141 to 150 of about 26,682 (264)
Alveolar and cystic echinococcosis: towards novel chemotherapeutical treatment options [PDF]
Echinococcus granulosus and Echinococcus multilocularis are cestode parasites, of which the metacestode (larval) stages cause the neglected diseases cystic echinococcosis (CE) and alveolar echinococcosis (AE), respectively. The benzimidazoles albendazole
Hemphill, A., Müller, J.
core
Group 6 metal complexes of Cr, Mo, and W supported by N‐heterocyclic carbenes are emerging as versatile platforms for homogeneous catalysis. This review highlights advances in reduction, hydrogen transfer, oxidation, and small molecule activation, revealing how ligand design controls reactivity and opens sustainable alternatives to noble‐metal ...
Beatriz Garcia +2 more
wiley +1 more source
Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley +1 more source
A polymeric hybrid material formulated as [MoO3(bis(pyrazolyl)methane)] has been prepared and used as a catalyst precursor for the complete oxidative desulfurization of a model diesel containing recalcitrant benzothiophene derivatives. The precursor is converted in situ to an oxodiperoxo active species which is retained in the recyclable extractant ...
Ana C. Gomes +4 more
wiley +1 more source
Acceptorless Dehydrogenative Polymerization
Acceptor‐less dehydrogenative polymerization (ADP) enables the atom‐economic step‐growth synthesis of different type of polymers directly from simple alcohols, releasing H2 as the sole by‐product. This review outlines the mechanistic foundations, catalytic systems, and emerging polymer architectures of ADP, highlighting its potential as a sustainable ...
Xin Liu +2 more
wiley +2 more sources
Crystal Facets Reactivity in Metal–Organic Frameworks
In this mini review, it is highlighted how the crystal facets reactivity of metal–organic frameworks can be dictated by bond strength, surface functionality, particle size, defect density, or crystal morphology. Precise control of these parameters enables deliberate exposure of crystal facets, leading to enhanced crystal surface accessibility and ...
Emilio Borrego‐Marin +1 more
wiley +1 more source
Metal‐Free, Chemoselective Reduction of Aromatic Nitro Compounds in Water at Room Temperature
A metal‐free, rapid, and chemoselective nitro reduction of aromatic compounds is developed using tetrahydroxydiboron as reducing agent and 4,4′‐bipyridine as organocatalyst. This green method provides an efficient entry to aromatic amines with high functional group tolerance in excellent yields under mild conditions using water as solvent. A metal‐free,
Maria Batzaki +2 more
wiley +1 more source
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami +9 more
wiley +1 more source
There is a lack of information on horse parasite management practices currently used by individual horse owners in Australia. A voluntary, anonymous online survey was developed for and distributed by Pony Club Australia to its members seeking information on horse population; housing; paddock, manure and parasite management; and owner attitudes.
W Nixon, P Buckley, R Butler
wiley +1 more source
In Fusarium asiaticum, two homologous SdhC subunits (FaSdhC1/C2) regulate sensitivity to SDHI fungicides: deletion of FaSDHC1 decreases sensitivity, while deletion of FaSDHC2 increases it. Multiple mutations in ΔFaSDHC2 confer resistance to SDHI fungicides.
Jichang Song +8 more
wiley +1 more source

