Human cytomegalovirus terminase inhibitors letermovir, tomeglovir, and the halogenated benzimidazoles modify DNA cleavage/packaging to generate a super-genomic DNA species by cleavage site skipping. [PDF]
Ourahmane A +9 more
europepmc +1 more source
Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele +7 more
wiley +1 more source
Bidirectional skeletal remodelling of SF<sub>5</sub>-nitrobenzenes into azepine, bicyclic, and benzimidazole frameworks. [PDF]
Bacho MZ +6 more
europepmc +1 more source
ABSTRACT Metal‐organic frameworks (MOFs) hold significant potential across numerous advanced disciplines due to their exceptional properties, including high specific surface area, tunable porosity, structural diversity, and customizable functionality. Increasing attention has been directed toward employing MOFs in coatings that offer both antimicrobial
Yanchun Zhao +7 more
wiley +1 more source
Metal-Free Tetraphenylethylene and Dibenzo[g,p]chrysene with Thiazolo[5,4‑<i>d</i>] Thiazole-Based Donor-Acceptor Conjugated Microporous Polymers for the Efficient Photocatalytic Synthesis of 2‑Substituted Benzimidazole. [PDF]
Mohamed MG, Wang PT, Karim H, Kuo SW.
europepmc +1 more source
Indocyanine green (ICG) is widely used for near‐infrared imaging but suffers from poor photostability. Here, an indocyanine green–inspired polymeric NIR chromophore is introduced, exhibiting intrinsically enhanced photostability and biocompatibility.
Su Bin Lee +14 more
wiley +1 more source
Identification and Evaluation of Benzimidazole- Agonists of Innate Immune Receptor NOD2. [PDF]
Wittle L +5 more
europepmc +1 more source
Ammonium halide salts serve as inorganic modifiers that lower the melting and glass transition temperatures of zeolitic imidazolate frameworks, enabling centimeter‐scale hybrid glasses and melt processing of otherwise unmeltable ZIF‐8. In situ imaging and pair distribution function analysis reveal salt infiltration, Zn─N bond disruption, and Zn–halide ...
Fengming Cao +7 more
wiley +1 more source
Synthesis and Bioactivity Studies of Benzimidazole-Chalcone Hybrids. [PDF]
Makgoathana HD +4 more
europepmc +1 more source
Programable metal–organic framework (MOF) architectures are revealed as versatile micro‐ and optoelectronic platforms, spanning low/high‐κ dielectrics, semiconductive frameworks, and electrically driven phosphor‐free white emitters. Metal nodes, π‐conjugated linkers, guests, and confined water emerge as decisive handles for tuning charge transport ...
Pounraj Thanasekaran +5 more
wiley +1 more source

