Results 91 to 100 of about 12,797 (181)

Antiprotozoal activity of flavonoids from Eupatorium arnottianum [PDF]

open access: yes, 2017
Dichloromethane and ethanol extracts of Eupatorium arnottianum were evaluated for invitroleishmanicidal activity. The dichloromethane extract produced 80% and 85% of growthinhibition on both Leishmania mexicana and Leishmania amazonensis promastigotes ...
Cazorla, Silvia Ines   +7 more
core  

Clinical Progression of Cardiac Chronic Trypanosoma cruzi Infection in a Long-Term Prospective Cohort from Rural Colombia

open access: yesPathogens
Chronic Trypanosoma cruzi infection remains a major cause of preventable cardiomyopathy in Latin America, yet prospective data from endemic rural populations after the interruption of domestic transmission are limited.
Mario J. Olivera   +3 more
doaj   +1 more source

Development of dissolution method for benznidazole tablets

open access: yesQuímica Nova, 2009
The aim of this work was the development of a dissolution method for benznidazole (BNZ) tablets. Three different types of dissolution media, two stirring speeds and apparatus 2 (paddle) were used.
Ádley Antonini Neves de Lima   +5 more
doaj   +1 more source

Benznidazole Treatment of Chagasic Encephalitis in Pregnant Woman with AIDS

open access: yesEmerging Infectious Diseases, 2013
We report a case of chagasic meningoencephalitis reactivation in a pregnant woman co-infected with Trypanosoma cruzi and HIV that was successfully managed with benznidazole and highly active antiretroviral therapy.
Margarita Bisio   +8 more
doaj   +1 more source

Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps [PDF]

open access: yes, 2016
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating illness of major significance throughout Latin America and an emergent threat to global public health.
Balouz, Virginia   +2 more
core   +1 more source

Benznidazole biotransformation in rat heart microsomal fraction without observable ultrastructural alterations: comparison to Nifurtimox-induced cardiac effects

open access: yesMemorias do Instituto Oswaldo Cruz, 2008
Benznidazole (Bz) and Nifurtimox (Nfx) have been used to treat Chagas disease. As recent studies have de-monstrated cardiotoxic effects of Nfx, we attempted to determine whether Bz behaves similarly.
María Montalto de Mecca   +3 more
doaj   +1 more source

Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole

open access: yesMemorias do Instituto Oswaldo Cruz
The effect of benznidazole (BZL) on the expression and activity of P-glycoprotein (P-gp, ABCB1) and multidrug resistance-associated protein 2 (MRP2, ABCC2), the two major transporters of endogenous and exogenous compounds, was evaluated in differentiated
Virginia G Perdomo   +5 more
doaj   +1 more source

Nanomedicines against Chagas disease: a critical review

open access: yesBeilstein Journal of Nanotechnology
Chagas disease (CD) is the most important endemic parasitosis in South America and represents a great socioeconomic burden for the chronically ill and their families.
Maria Jose Morilla   +2 more
doaj   +1 more source

Drug-resistant epimastigotes of Trypanosoma cruzi and persistence of this phenotype after differentiation into amastigotes [PDF]

open access: yes, 1995
Des formes épimastigotes du parasite #Trypanosoma cruzi$ ont été rendues résistantes au benznidazole en utilisant, in vitro, une pression médicamenteuse continue.
Barnabé, Christian   +2 more
core  

Cerebral trypanosomiasis and AIDS

open access: yesArquivos de Neuro-Psiquiatria, 2002
A 36 year-old black female, complaining of headache of one month's duration presented with nausea, vomiting, somnolence, short memory problems, loss of weight, and no fever history. Smoker, intravenous drugs abuser, promiscuous lifestyle.
Antunes Apio Claudio Martins   +6 more
doaj  

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