Results 1 to 10 of about 8,244 (233)
Nitazoxanide and tizoxanide demonstrate high levels of in vitro activity against metronidazole-susceptible and metronidazole-resistant Trichomonas vaginalis clinical isolates [PDF]
Microbiology SpectrumTrichomonas vaginalis is the most common non-viral sexually transmitted infection worldwide. We compared the in vitro activity of the thiazolide nitazoxanide (NTZ) and its metabolite, tizoxanide (TIZ), with the activity of the Food and Drug ...
Keonte J. Graves +5 more
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Journal of Pharmacy and Bioallied SciencesBackground: Periodontitis is a slow progressing infection and has profound systemic implications. The influence of various therapeutic drugs to inhibit inflammation and promote bone regeneration has been studied.
Prabhu Manickam Natarajan
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Determination of Residues of 5-Nitroimidazoles and Their Metabolites in Eggs by Isotope Dilution-Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry [PDF]
Shipin Kexue, 2023 A rapid method was developed and validated for the simultaneous identification and quantitation of the residues of 5-nitroimidazoles and their metabolites in eggs by isotope dilution-ultra-high performance liquid chromatography-tandem mass spectrometry ...
QIU Xiaoyi, WANG Dongmei, LI Jiakuan, XU Qing, WANG Mengying, GUAN Zhuolong, LU Yuepeng, TU Fengqin
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Design and synthesis of 4-nitroimidazole derivatives with potential antitubercular activity
Тонкие химические технологии, 2023 Objectives. To develop the procedures for synthesis of hybrid molecules with potential anti-tubercular activity containing heterocyclic cores of 4-nitroimidazole and 1,3,4-thiadiazole within the framework of a double-drug strategy and predict bioactivity
T. S. Vedekhina +2 more
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Compounds, 2023 The discovery of azomycin provided the major impulse for the systematic search for medicines showing activity against anaerobic protozoa. Nowadays, many other interesting applications have been found for nitroimidazoles as therapeutic agents.
Justyna Żwawiak, Lucjusz Zaprutko
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In Vitro Effect of 5-Nitroimidazole Drugs against Trichomonas vaginalis Clinical Isolates
Microbiology Spectrum, 2022 Infections with the sexually transmitted parasite Trichomonas vaginalis are normally treated with metronidazole, but cure rates are suboptimal and recurrence rates following treatment are high.
Andile Mtshali +5 more
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Pharmaceuticals, 2021 Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a curable airborne disease currently treated using a drug regimen consisting of four drugs.
Klaudia T. Angula +2 more
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Biomédica: revista del Instituto Nacional de Salud, 2020 Introducción. Trypanosoma cruzi, agente causal de la enfermedad de Chagas, exhibe una sustancial heterogeneidad fenotípica y genotípica que puede influir en las variaciones epidemiológicas y clínicas de la enfermedad, así como en la sensibilidad a los ...
Nidia Acosta +6 more
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Chemosensitization by lipophilic nitroimidazoles [PDF]
British Journal of Cancer, 1983 We have carried out experiments to determine the response of tumours and normal tissues in the C3H mouse to the combination of lipophilic nitroimidazoles and CCNU, cyclophosphamide or melphalan. The nitroimidazoles studied were Ro 07-1902 (1902) and benznidazole (Ro 07-1051, BENZO). Maximum enhancement of CCNU response in the KHT sarcoma by 2.5 mmol kg-
P R, Twentyman, P, Workman
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Tumor Hypoxia Imaging Agents in Nuclear Medicine
Trends in Peptide and Protein Sciences, 2017 Hypoxia is due to imbalance in oxygen supply and oxygen demand compromising biological functions of cells. Since tumor hypoxia results in angiogenesis, apoptosis, metastasis, tumor aggressiveness and treatment failure, in vivo measurement is required ...
Mahtab Mohammadpour, Soraya Shahhosseini
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