Results 31 to 40 of about 5,742 (217)
Synthesis of N-7-Substituted Purines from Imidazole Precursors
Molecules, 1999 Synthesis of purines and purine mono-1-oxides from the respective 5-substituted 4-nitroimidazole derivatives is described. The commercially available 4-nitroimidazole, in a few simple steps (including Vicarious Nucleophilic Substitution of Hydrogen), was
Stanislaw Ostrowski
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Molbank, 2022 Nitroimidazoles are pharmacophoric groups responsible for important antiparasitic activity against several infectious diseases. 2-Nitroimidazoles are found in some antiparasitic drugs and are one of the main moieties responsible for the biological ...
Afonso Santine M. M. Velez +5 more
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Journal of Chemistry, 2018 A novel method for the rapid separation and determination of five polar 5-nitroimidazoles in water from different sources by pressurized capillary electrochromatography has been developed.
Sulan Liao, Qilin Weng
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Emerging Infectious Diseases, 2023 New classes of antitubercular drugs, diarylquinolines and nitroimidazoles, have been associated with improved outcomes in the treatment of drug-resistant tuberculosis, but that success is threatened by emerging drug resistance.
James Millard +3 more
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Crystal structure of 2-{[1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yloxy]carbonyl}benzoic acid
Acta Crystallographica Section E, 2014 In the title compound, C15H15N3O6, the dihedral angle between the planes of the benzene and imidazole rings is 34.93 (10)°. An intramolecular C—H...O hydrogen bond is observed.
Hafiz Abdullah Shahid +4 more
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Antibiotic residues in poultry‐derived foods and associated human health risks: a systematic review
Journal of the Science of Food and Agriculture, EarlyView.Abstract Antibiotic residues in poultry‐derived foods remain a food‐safety concern because of their implications for regulatory compliance, antimicrobial stewardship, and consumer exposure. This review synthesized evidence published between 2016 and April 2026 on the occurrence of antibiotic residues in poultry‐derived foods, analytical approaches ...
Ana Clara Nogueira Alves +3 more
wiley +1 more source
Tratamiento de aguas para la eliminación de antibióticos -nitroimidazoles- mediante adsorción sobre carbón activado y tecnologías avanzadas de oxidación [PDF]
, 2010 El objetivo general de esta Tesis Doctoral es estudiar la eliminación de antibióticos, concretamente nitroimidazoles, del agua mediante procesos de adsorción/bioadsorción en carbones activados y usando diferentes tecnologías basadas en la ozonización ...
Prados Joya, Gonzalo
core +1 more source
Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins
Redox Biology, 2021 Tumour hypoxia negatively impacts therapy outcomes and continues to be a major unsolved clinical problem. Nitroimidazoles are hypoxia selective compounds that become entrapped in hypoxic cells by forming drug-protein adducts.
Faisal Bin Rashed +13 more
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Smart Molecules, EarlyView.Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +1 more source
Nature Communications, 2023 Severe outbreaks and deaths have been linked to the emergence and global spread of fluoroquinolone-resistant Clostridioides difficile over the past two decades. At the same time, metronidazole, a nitro-containing antibiotic, has shown decreasing clinical
Abiola O. Olaitan +13 more
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