Results 31 to 40 of about 56,478 (190)

Polycyclic aromatic hydrocarbons and esophageal squamous cell carcinoma [PDF]

, 2012
Esophageal cancer (EC) is the 8th most common cancer and the 6th most frequent cause of cancer mortality worldwide. Esophageal squamous cell carcinoma (ESCC) is the most common type of EC.
Dawsey, S.M., Malekzadeh, R., Roshandel, G., Semnani, S.   +3 more
core  

Metal‐Free Covalent Organic Frameworks for Photocatalytic CO2 Reduction

ChemistryEurope, EarlyView.
This review presents an environmentally sustainable strategy to address the critical issue of escalating atmospheric CO2 levels. It explores the application of metal‐free covalent organic frameworks in a photocatalytic approach, offering a green and efficient strategy for carbon dioxide reduction and contributing to climate change mitigation.
Supriti Dutta, Akhtar Alam, Pekham Chakrabortty, Pradip Pachfule   +3 more
wiley   +1 more source

A comparison of PAH emission sampling methods (cyclone, impactor) in particulate and gaseous phase [PDF]

, 2018
Four different domestic heating boilers and four types of fuel (lignite, wet wood, wood pellets and mixed fuel) were tested, and the emissions of the particulate matter (PM) and polycyclic aromatic hydrocarbons (PAHs) were correlated. Dekati low-pressure
Hopan, František, Horák, Jiří, Koloničný, Jan, Krpec, Kamil, Kubesa, Petr, Kuboňová, Lenka, Plachá, Daniela   +6 more
core   +1 more source

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

Quantitative Determination of Benzo[a]pyrene in Foodstuffs Using Benzo[a]pyrene[G-3H]

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1977
A method for quantitative determination of nano gram level of benzo[a]pyrene (BP) in foodstuffs using tritiated BP (3H-BP) was described. Extracts from foodstuffs, having been added a certain amount of 3H-BP, were fractionated by column chromatography on Florisil, and thinlayer chromatography on acetylated cellulose. Concentration and radio activity of
Yoshito MASUDA, Kyoko SHIMAMURA, Hiroshige YANO   +2 more
openaire   +2 more sources

Evaluation of polycyclic aromatic hydrocarbons using analytical methods, toxicology, and risk assessment research: seafood safety after a petroleum spill as an example. [PDF]

, 2014
BackgroundPolycyclic aromatic hydrocarbons (PAHs) are abundant and widespread environmental chemicals. They are produced naturally and through man-made processes, and they are common in organic media, including petroleum.
Ansari, Shakeel, Blake, Diane, Echsner, Stephen, Elferink, Cornelis, Fernando, Harshica, Frickel, Scott, Gauthe, David, Howard, Jessi, Kane, Andrew, Miller, Charles, Nguyen, Daniel, Overton, Edward, Simon, Bridget, Trapido, Edward, Wickliffe, Jeffrey, Wilson, Mark   +15 more
core   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

A screen for Benzo(a)pyrene in fish samples from crude oil polluted environments [PDF]

, 2008
Several studies have shown that exposure to Benzo(a)pyrene increases the risk of cancer. In this study several fish samples from Niger the Delta region of Nigeria were screened for the presence of Benzo(a)pyrene.
Anyakora, Chimezie., Arbabi, Mohsen., Coker, Herbert.   +2 more
core  

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source