Results 71 to 80 of about 73,231 (295)

Toxic effects of complex mixed organic compounds in aerosols on Skeletonema costatum [PDF]

E3S Web of Conferences
Considering the complexity of organic components in aerosols, this study aimed to compare the toxic effects of mixed PAHs and the highly toxic benzo[a]pyrene on Skeletonema costatum (S. costatum).
Li Jiajia, Feng Lei
doaj   +1 more source

Induced Nucleophilic Substitution in Benzo[a]pyrene [PDF]

Nature, 1973
Cavalieri and Calvin have proposed1,2 that the carcinogenic action of benzo[a]pyrene (BaP) may arise from aryl hydroxylase induced binding to nucleophilic cellular components. Their theory proposes that attack by electrophilic oxygen, produced in the hydroxylase system, occurs at the 6 position of the hydrocarbon to give a carbonium ion, localized ...
M D, Johnson, M, Calvin
openaire   +2 more sources

Polycyclic aromatic hydrocarbons and esophageal squamous cell carcinoma [PDF]

, 2012
Esophageal cancer (EC) is the 8th most common cancer and the 6th most frequent cause of cancer mortality worldwide. Esophageal squamous cell carcinoma (ESCC) is the most common type of EC.
Dawsey, S.M., Malekzadeh, R., Roshandel, G., Semnani, S.   +3 more
core  

Metal‐Free Covalent Organic Frameworks for Photocatalytic CO2 Reduction

ChemistryEurope, EarlyView.
This review presents an environmentally sustainable strategy to address the critical issue of escalating atmospheric CO2 levels. It explores the application of metal‐free covalent organic frameworks in a photocatalytic approach, offering a green and efficient strategy for carbon dioxide reduction and contributing to climate change mitigation.
Supriti Dutta, Akhtar Alam, Pekham Chakrabortty, Pradip Pachfule   +3 more
wiley   +1 more source

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

Sand to Root Transfer of PAHs and PCBs by Carrots Grown on Sand with Pure Substances and Biosolids Amended Sand [PDF]

, 2006
A study on behaviour of trace organic compounds (Polycyclic Aromatic Hydrocarbons, PAH, and Polychlorinated Biphenyls, PCB) in a sand-plant system has been carried out, with the reclamation of wastewater treatment plant biosolids for agriculture in mind.
Patria, Lucie, Sablayrolles, Caroline, Silvestre, Jérôme, Vignoles-Montrejaud, Mireille   +3 more
core   +3 more sources

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Effects of smoke flavoring using different wood chips and barbecuing on the formation of polycyclic aromatic hydrocarbons and heterocyclic aromatic amines in salmon fillets.

PLoS ONE, 2020
Herein, the concentrations of food toxicants, polycyclic aromatic hydrocarbons (PAHs) and heterocyclic aromatic amines (HAAs), in salmon fillets smoke flavored with different smoking wood chips (oak, apple, bourbon soaked oak, cherry and hickory) and ...
Emel Oz
doaj   +1 more source

Technogenic pollution of pine forests by polycyclic aromatic hydrocarbons [PDF]

Сибирский лесной журнал, 2015
Anthropogenic pollution of boreal forests by polycyclic aromatic hydrocarbons was assessed by polycyclic aromatic hydrocarbon (PAH) concentrations in needles of Scots pine (Pinus sylvestris L.) trees growing in the vicinity of the Bratsk aluminium ...
O. V. Kalugina, E. N. Taranenko, T. A. Mikhailova, O. V. Shergina   +3 more
doaj   +1 more source

Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1 [PDF]

Carcinogenesis, 1998
Benzo[a]pyrene (B[a]P), a ubiquitous environmental, tobacco and dietary carcinogen, has been implicated in human cancer etiology. The role of human cytochrome P450 1B1 in the metabolism of B[a]P is poorly understood. Using microsomal preparations of human P450 1A1, 1A2 and 1B1 expressed in baculovirus-infected insect cells, as well as human and rat ...
J H, Kim, K H, Stansbury, N J, Walker, M A, Trush, P T, Strickland, T R, Sutter   +5 more
openaire   +2 more sources