Results 71 to 80 of about 22,552 (198)

Examining the role of freebase nicotine in the harm reduction potential of oral nicotine pouches versus moist snuff: A randomized crossover trial

Addiction, EarlyView.
Abstract Background and aims Oral nicotine pouches (ONPs) contain varying proportions of freebase nicotine (FBN), with higher FBN expected to increase nicotine delivery across the oral mucosa. Because ONPs contain fewer toxicants than moist snuff and may serve as a reduced harm alternative for smokeless tobacco, we compared how the FBN in ONPs affects ...
Brittney Keller‐Hamilton, Hayley Curran, Leanne Atkinson, Sriya Suraapaneni, Alice Hinton, Kirsten Chrzan, Darren Mays, Ahmad El‐Hellani, Clark W. Wilson, Marielle C. Brinkman, Theodore L. Wagener   +10 more
wiley   +1 more source

The effect of doxorubicin on rats that received toxic and carcinogenic benzo(a)pyrene.

Folia Histochemica et Cytobiologica, 2008
Benzo(a)pyrene (B(a)P) is a polycyclic aromatic hydrocarbon with carcinogenic and toxic effects. Doxorubicin is a DNA-interacting drug widely used in chemotherapy.
Hasan Veysi Gunes, Ayse Basaran, Didem Cosan, Irfan Degirmenci, Erinc Aral   +4 more
doaj   +1 more source

The Price of Prosperity? A Historical Account of Regulating Industrial Pollution in the Netherlands

Regulation &Governance, EarlyView.
ABSTRACT Regulatory governance and state‐corporate crime studies link persistent industrial pollution to long‐term regulatory–industry interactions, yet little is known about how these interactions evolve and become entrenched. This article examines two enduring cases of industrial pollution in the Netherlands—Hoogovens/Tata Steel and DuPont de Nemours/
Karin van Wingerde, Lieselot Bisschop, Sammie Verbeek, Julie Le Sage   +3 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Transcriptomic Analysis Reveals Core Genes and Mechanisms Linking Grilled Food Toxicants (4‐HNE, BaP, PhIP) to NASH‐HCC Progression

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This study identifies a six‐gene signature (GSTA1, EPHX1, CYP2E1, GPX3, ALB, TF) that mediates how grilled food toxicants (4‐HNE, BaP, PhIP) synergistically drive NASH‐to‐HCC progression via oxidative stress, metabolic dysfunction, and immune microenvironment remodeling, providing a robust diagnostic nomogram for early risk stratification.
Bingbing Qin, Ye Zhang, Na Li, Jing Li, Yuehua Luo, Xi Tang, Ruisheng Zhou, Tianqi Cui, Ying Tang   +8 more
wiley   +1 more source

PAHs Content in Polish Smoked Meat Prepared with Traditional Method

Acta Universitatis Cibiniensis. Series E: Food Technology
Meat smoking is an old and efficient method of meat treatment, resulting in the preparation of meat with specific properties, improved taste, and modified the physical and chemical properties of treated meats.
Kowalczyk Karolina, Tereszkiewicz Krzysztof, Antos Piotr   +2 more
doaj   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

International Journal of Cancer, Volume 159, Issue 5, Page 1311-1321, 1 September 2026.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn, Rachel Lawrence, Hasan Haboubi, Hamsa Naser, Kate Hurlow, Ume‐Kulsoom Shah, Lisa Williams, Sarah Gwynne, Owen Bodger, Jiri Zavadil, Francois Virard, Shareen Doak, Laura E. Thomas, Gareth Jenkins   +13 more
wiley   +1 more source

Filtration d’une huile dopée avec quatre hydrocarbures aromatiques polycycliques (HAP) sur des plaques garnies en charbon actif

Oléagineux, Corps gras, Lipides, 2012
Powdered activated carbon is used in oils and fats refining to bleach and purify vegetable oils and fish oils. Actually, this powder makes it possible to detoxify crude fish oils and to eliminate contaminants like PAH, dioxin and PCB.
Sidani Marion, Gaud Marie, Pagès Xavier, Morin Odile, Gouband Morgan, Buchoux Jérôme, Goulet Jérémy, Birot Céline, Galan Virginie   +8 more
doaj   +1 more source

Atmospheric Aerosol Neurotoxicity and Parkinson's Disease: Mechanisms and Perspectives

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Schematic overview of the pathways and pathological mechanisms connecting atmospheric aerosol exposure to PD. Atmospheric aerosols, including PM2.5 and nanometer/ultrafine particles loaded with metal particles, persistent organic pollutants (POPs), polycyclic aromatic hydrocarbons (PAHs) and dioxins, enter the body predominantly via pulmonary ...
Yitian Gao, Minxiang Dong, Chenyang Duan, Xiaohan Zheng, Liming Qu   +4 more
wiley   +1 more source

Concentration and source analysis of polycyclic aromatic hydrocarbons in PM2.5 during heating period in Yantai City

环境与职业医学
BackgroundPolycyclic aromatic hydrocarbons (PAHs) are widely known atmospheric pollutants, which can cause serious harm to human body and ecological environment.
Tiantian ZHANG, Ying WANG, Zhiyu WANG, Tianran ZHANG, Wenna GUO, Songsong WANG, Xiaoyu ZHANG   +6 more
doaj   +1 more source