Results 81 to 90 of about 73,231 (295)

A screen for Benzo(a)pyrene in fish samples from crude oil polluted environments [PDF]

open access: yes, 2008
Several studies have shown that exposure to Benzo(a)pyrene increases the risk of cancer. In this study several fish samples from Niger the Delta region of Nigeria were screened for the presence of Benzo(a)pyrene.
Anyakora, Chimezie.   +2 more
core  

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk   +4 more
wiley   +1 more source

Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants [PDF]

open access: yesCarcinogenesis, 2001
Cytochrome P450 1A1 (CYP1A1) plays a key role in the metabolism of carcinogens, such as benzo[a]pyrene (B[a]P) and metabolites to ultimate carcinogens. Three human allelic variants, namely wild-type (CYP1A1.1), CYP1A1.2 (I462V) and CYP1A1.4 (T461N), were coexpressed by coinfection of baculovirus-infected insect cells with human NADPH-P450 reductase ...
D, Schwarz   +4 more
openaire   +2 more sources

Validasi Metode Analisis Dalam Penetapan Kadar Benzo(a)piren Pada Ikan Bakar [PDF]

open access: yes, 2016
VALIDASI METODE ANALISIS DALAM PENETAPAN KADAR BENZO(A)PIREN PADA IKAN BAKAR Windi Astuti1), Sri Sudewi1), Henki Rotinsulu1) 1)Program Studi Farmasi FMIPA UNSRAT Manado, 95115 ABSTRACT Benzo (a) pyrene is carcinogenic ...
Astuti, W. (Windi)
core   +2 more sources

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert   +5 more
wiley   +1 more source

Analysis of benzo(a)pyrene in airborne particulates by gas chromatography [PDF]

open access: yes
A routine method was developed to measure benzo(a)pyrene in airborne particulates. Samples were collected on a filter and the organic portion was extracted with cyclohexane. The polynuclear hydrocarbon (PNHC) fraction was separated from the aliphatics by
Luedecke, E.
core   +1 more source

Extent and toxicity of contaminated marine sediments in Southeastern Florida [PDF]

open access: yes, 2004
Thirty sites were sampled in southern Biscayne Bay and Manatee Bay in December 1999 to determine the extent of toxicity in sediments. Analyses and assays included: pesticides and phenols in seawater; chemical contaminants in sediment; amphipod mortality,
Cantillo, A. Y., Lauenstein, G. G.
core  

Optimization of pressurized liquid extraction using a multivariate chemometric approach and comparison of solid phase extraction cleanup steps for the determination of polycyclic aromatic hydrocarbons in mosses [PDF]

open access: yes, 2012
A factorial design was used to optimize the extraction of polycyclic aromatic hydrocarbons (PAHs) from mosses, plants used as biomonitors of air pollution.
Foan, Louise, Simon, Valérie
core   +3 more sources

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal   +7 more
wiley   +1 more source

Effect of Methomyl on the Phenobarbital and Benzo [a] Pyrene Induced Hepatic Microsomal Mixed Function Oxidase System in Rats [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2011
Methomyl (Lannate) is a pesticide widely used to control of insects in grape gardens. Methomyl treatment induces significant alteration in mixed function oxidase system.
Jyotsna A. Patil1, Arun J. Patil1*, Ajit V. Sontakke1, Satish D. Kalme2 and Sanjay P. Govindwar3
doaj  

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