Association between prescription patterns and primary care clinic closures in South Korea: A longitudinal retrospective cohort study. [PDF]
Kim HJ, Cho B, Yun JM.
europepmc +1 more source
Benzodiazepines: a summary of pharmacokinetic properties.
D J Greenblatt +3 more
openalex +1 more source
Tumor‐related epilepsy in glioma: A multidisciplinary overview
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci +29 more
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Supporting Patients Through Benzodiazepine Tapering: A New Joint Clinical Practice Guideline. [PDF]
Zgierska AE, Boyle MP, Conigliaro J.
europepmc +1 more source
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire +9 more
wiley +1 more source
Patients with Benzodiazepine Intoxication Require Neurological and Psychiatric Examination in Order to Guide and Monitor Withdrawal. [PDF]
Zarrouk S, Finsterer J.
europepmc +1 more source
Abstract Objective Current preclinical epilepsy drug screening relies on animal models that poorly reflect human neurophysiology, leading to high failure rates in clinical translation. We aimed to establish a human in vitro model using human‐induced pluripotent stem cell (hiPSC)–derived cortical neurons cultured on multielectrode arrays (MEAs), capable
Joshua Nicholls +13 more
wiley +1 more source
What does data on adverse reactions reveal about benzodiazepines and suicide-related risk?: A disproportionality analysis using FDA FAERS pharmacovigilance data. [PDF]
Guo W, Zhang C, Yang R, Yan L.
europepmc +1 more source
Familial adult myoclonus epilepsy: A comprehensive diagnostic strategy for clinical practice
Abstract Familial adult myoclonus epilepsy (FAME) is a genetic neurological disorder characterized by cortical myoclonus and epileptic seizures with clinical features that overlap with other movement disorders and epileptic syndromes, particularly essential tremor (ET), progressive myoclonic epilepsy (PME), and juvenile myoclonic epilepsy (JME).
Yitao Lu +14 more
wiley +1 more source
Abstract Objective In women with epilepsy who are treated with antiseizure medications (ASMs), folate concentrations in maternal serum may not be a good indicator of fetal folate supply, because ASMs can interfere with folate handling by the placenta. We aimed to assess the transplacental folate transfer at birth in persons with epilepsy in comparison ...
Erez Berman +6 more
wiley +1 more source

