Results 231 to 240 of about 214,407 (289)
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Critical Care Clinics, 1995
Most patients in the intensive care unit experience pain and anxiety, which are treated most commonly with an opioid or a benzodiazepine. These compounds are effective and have a well-established safety record. With the exception of associated respiratory depression, they have a relatively wide therapeutic window.
M J, Murray +2 more
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Most patients in the intensive care unit experience pain and anxiety, which are treated most commonly with an opioid or a benzodiazepine. These compounds are effective and have a well-established safety record. With the exception of associated respiratory depression, they have a relatively wide therapeutic window.
M J, Murray +2 more
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Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1984
Dependence to benzodiazepines is difficult to induce in animals but has been induced by high doses in man. Case reports of benzodiazepine dependence are rare compared with the usage of these drugs, but provide no proper epidemiological framework for the estimation of risk.
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Dependence to benzodiazepines is difficult to induce in animals but has been induced by high doses in man. Case reports of benzodiazepine dependence are rare compared with the usage of these drugs, but provide no proper epidemiological framework for the estimation of risk.
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Neuroscience & Biobehavioral Reviews, 1985
This article sets the background for the following series of articles on the behavioral actions of drugs acting at the GABA-benzodiazepine receptor complex. The articles provide detailed analyses of particular behaviors and emphasise the danger of interpreting all behavioral effects in terms of anxiety.
S E, File, S J, Cooper
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This article sets the background for the following series of articles on the behavioral actions of drugs acting at the GABA-benzodiazepine receptor complex. The articles provide detailed analyses of particular behaviors and emphasise the danger of interpreting all behavioral effects in terms of anxiety.
S E, File, S J, Cooper
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2015
Benzodiazepines have been in clinical use since the 1960s. Benzodiazepines act through allosteric modulation of the GABAA receptor to enhance the activity of GABA, an inhibitory neurotransmitter, resulting in a slowing of neurotransmission and sedative and anxiolytic effects.
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Benzodiazepines have been in clinical use since the 1960s. Benzodiazepines act through allosteric modulation of the GABAA receptor to enhance the activity of GABA, an inhibitory neurotransmitter, resulting in a slowing of neurotransmission and sedative and anxiolytic effects.
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Benzodiazepine and Non-Benzodiazepine Anxiolitics
Psychopathology, 1984A review of anxiolytic drugs is presented, including ethyl alcohol, barbiturates, diphenylmethane derivatives, glycerol and propanediol derivatives, antipsychotics, and antidepressants. Focus on the benzodiazepines and their metabolism and method of action follows.
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Journal of Psychiatric Research, 1990
The frequency and quantity of alcohol consumption is a major consideration in patients who need treatment with benzodiazepines. Alcohol affects the GABA-benzodiazepine-chloride ionophore complex and has an agonist-like action. Thus, additive interactions should be expected from combining alcohol with benzodiazepines. Furthermore, alcohol has clinically
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The frequency and quantity of alcohol consumption is a major consideration in patients who need treatment with benzodiazepines. Alcohol affects the GABA-benzodiazepine-chloride ionophore complex and has an agonist-like action. Thus, additive interactions should be expected from combining alcohol with benzodiazepines. Furthermore, alcohol has clinically
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Benzodiazepines for schizophrenia
2007Many people with schizophrenia do not achieve a satisfactory treatment response with ordinary antipsychotic drug treatment. In these cases, various add-on medications are used, among them benzodiazepines.To review the effects of benzodiazepines for the treatment of schizophrenia and schizophrenia-like psychoses.The reviewers searched the Cochrane ...
A, Volz +3 more
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Why won’t it stop? The dynamics of benzodiazepine resistance in status epilepticus
Nature Reviews Neurology, 2022R. Burman +6 more
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Journal of Affective Disorders, 1987
Benzodiazepines (BDPs) are widely used drugs that are effective in controlling the symptoms of anxiety. Tolerance develops rapidly to some of the effects but not to anxiolytic effect in most patients. Dependence occurs at usual therapeutic doses and in a small proportion of patients is accompanied by an enormous increase in the dose taken. The majority
R P, Swinson, J C, Pecknold, M E, Kirby
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Benzodiazepines (BDPs) are widely used drugs that are effective in controlling the symptoms of anxiety. Tolerance develops rapidly to some of the effects but not to anxiolytic effect in most patients. Dependence occurs at usual therapeutic doses and in a small proportion of patients is accompanied by an enormous increase in the dose taken. The majority
R P, Swinson, J C, Pecknold, M E, Kirby
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Clinical Obstetrics & Gynecology, 2019
Benzodiazepine use and dependence are on the rise as well as the number of deaths attributable to the combination of opioids and benzodiazepines. Anxiety, the most frequent condition for which benzodiazepines are prescribed, occurs commonly, and is increasingly noted to coincide with pregnancy.
Jaye M, Shyken +3 more
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Benzodiazepine use and dependence are on the rise as well as the number of deaths attributable to the combination of opioids and benzodiazepines. Anxiety, the most frequent condition for which benzodiazepines are prescribed, occurs commonly, and is increasingly noted to coincide with pregnancy.
Jaye M, Shyken +3 more
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