Results 261 to 270 of about 138,894 (338)

Recent Advances in the Synthesis of Annelated 1,4-Benzodiazepines

, 1986
Chengalva Venkata Ratnam, Ghulam Mohiuddin, P. S. N. REDDY, Ahmed Khalil   +3 more
openalex   +1 more source

Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABAA receptors

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades, Marcella Bassetto, Marius C. Staiculescu, Gayathri Swaminath, Samuel J. Fountain   +4 more
wiley   +1 more source

A Scoping Review of the Emergence of Novel Synthetic Opioids in Australian Drug Markets: What Does This Mean for Harm Reduction Responses?

Drug and Alcohol Review, EarlyView.
ABSTRACT Issues Rising synthetic opioid deaths in North America, and the emergence of nitazene harms has driven concern about novel synthetic opioids (NSO) in Australia. This scoping review aimed to map what is known about NSOs in Australia. Approach Scoping review of peer‐reviewed and grey literature on NSO detections and harms.
Emmanuel Mammoliti, Suzanne Nielsen, Amanda Roxburgh   +2 more
wiley   +1 more source

Molecular Cloning and Expression of cDNA Encoding a Peripheral-type Benzodiazepine Receptor

, 1989
Rolf Sprengel, P. Werner, P. H. Seeburg, Alexey G. Mukhin, Mariarita Santi, Dennis R. Grayson, Alessandro Guidotti, Karl E. Krueger   +7 more
openalex   +1 more source

Global Perspectives on Kava: A Narrative Systematic Review of the Health Effects, Economic and Social Impacts and Policy Considerations

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction Kava is a plant‐based drug central to many Pacific Island cultures, yet its physiological and psychological effects remain contested and poorly understood. Additionally, the broader social, economic, and policy consequences of kava trade and consumption are unclear.
George Economidis, Michelle Lynch, Sophia Taylor, Winifred Asare‐Doku, Georgina Macpherson, Louisa Degenhardt, Michael Farrell, Thomas Santo Jr   +7 more
wiley   +1 more source

Relationships Between Motives for Cannabis and Cannabidiol Use in People Who Co‐Use: Results From the European Web Survey on Drugs

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction Cannabis is one of the most commonly used psychoactive substances globally. Cannabidiol (CBD) is a non‐intoxicating cannabis compound increasingly used for various purposes, especially among cannabis users. However, to date, there are no data on the relationships between cannabis and CBD motives.
Davide Fortin, Vincent Leroy, Patrizia Carrieri, João Matias, Tangui Barré   +4 more
wiley   +1 more source

Gender and Overdose Risk Factors Among Clients Entering Residential Treatment for Opioid Use

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction The period post‐residential treatment for opioid use is associated with heightened risk of overdose. The current study aims to: (i) describe characteristics of men and women attending residential treatment for primary opioid use; (ii) identify classes of clients based on primary opioid and other substance/s of concern and (iii ...
Chloe J. Haynes, Alison K. Beck, Peter J. Kelly, Mei Lin Lee, Robert Stirling, Suzie Hudson, Laura Robinson, Michele Campbell, Carolyn Stubley, Briony Larance   +9 more
wiley   +1 more source

Drugs and Drowning: The Toxicology of Adult Drownings in Baths and Hot Tubs in Australia, 2015–2024

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction Drowning is the third leading cause of unintentional injury death. We aimed to determine the toxicology and circumstances of all adult drowning deaths that occurred in bath/hot tubs in Australia over the period 2015–2024. Methods Retrospective study of all adult (≥ 15 years) drowning deaths in baths or hot tubs in Australia (1 ...
Shane Darke, Michael Farrell, Johan Duflou, Caroline Copeland, Emmert Roberts   +4 more
wiley   +1 more source

Characteristics of Drug‐Related Deaths Among Individuals Engaged in Sex Work in the United Kingdom, 1997–2023

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction Individuals engaged in sex work are an understudied population recognised to be at differential risk of experiencing drug‐related harms. We aimed to determine the case characteristics, circumstances of death and type of implicated drugs among sex workers dying due to drug‐related causes.
Emmert Roberts, Sharmila Parmanand, Caroline Copeland   +2 more
wiley   +1 more source

Management of Refractory Catatonia Associated With OCD Exacerbation in a Patient With Bipolar I Disorder: A Case Report

Bipolar Disorders, EarlyView.
Jiyun Lee, Rahat Hossain, Nikola Grujich, Ayal Schaffer   +3 more
wiley   +1 more source