Results 91 to 100 of about 207,949 (383)

Anxiolytic Effects of Indole Alkaloids From Rauvolfia ligustrina in Adult Zebrafish: Involvement of the GABAergic and 5‐HT Systems

Chemistry &Biodiversity, EarlyView.
ABSTRACT Benzodiazepines are widely used in the treatment of anxiety, but their use may be interrupted due to side effects. This study evaluated the indole alkaloids isocarapanaubine (indole alkaloid 1 [AIN1]) and 18‐β‐hydroxy‐3‐epi‐α‐yohimbine (indole alkaloid 2 [AIN2]), extracted from Rauvolfia ligustrina, in adult zebrafish.
Nádia Aguiar Portela Pinheiro, Ivana Carneiro Romão, Amanda Maria Barros Alves, Sônia Maria Costa Siqueira, Jane Eire Silva Alencar de Menezes, Emmanuel Silva Marinho, Márcia Machado Marinho, Herbert de Sousa Magalhães, Andreia Ferreira de Castro Gomes, Otília Deusdênia Loiola Pessoa, Hélcio Silva dos Santos   +10 more
wiley   +1 more source

Insights into the Silylation of Benzodiazepines Using N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA): In Search of Optimal Conditions for Forensic Analysis by GC-MS

Molecules
Silylation is a widely used derivatization technique for the gas chromatographic analysis of benzodiazepines, a class of psychoactive drugs commonly encountered in forensic and biological samples.
Eleazar Vargas Mena, Eliana R. Herrera Giraldo, Jovanny A. Gómez Castaño   +2 more
doaj   +1 more source

The pharmacist’s response to the needs of patients undergoing treatment with psychotropic medication [PDF]

, 1999
The usage of psychotropic (Table 1) medication is considerable world wide. In Malta, this can be attested to by the numerous studies that have been conducted by the University of Malta Department of Pharmacy (in conjuction with other institutions and ...
Sant Fournier, Mary Ann
core  

Mortality and Cumulative Exposure to Antipsychotics, Antidepressants, and Benzodiazepines in Patients With Schizophrenia: An Observational Follow-Up Study.

American Journal of Psychiatry, 2015
OBJECTIVE Although mortality related to psychotropic medications has received much attention in recent years, little is known about the relationship between risk of death and cumulative antipsychotic load, and even less about the relationship between ...
J. Tiihonen, E. Mittendorfer-Rutz, M. Torniainen, K. Alexanderson, A. Tanskanen   +4 more
semanticscholar   +1 more source

Alcohol Withdrawal Syndrome: Benzodiazepines and Beyond.

Journal of clinical and diagnostic research : JCDR, 2015
Alcohol dependence is an increasing and pervasive problem. Alcohol withdrawal symptoms are a part of alcohol dependence syndrome and are commonly encountered in general hospital settings, in most of the departments.
Ankur Sachdeva, Mona Choudhary, Mina Chandra   +2 more
semanticscholar   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia

Frontiers in Aging Neuroscience, 2020
Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice due to their anxiolytic, hypnotic, and muscle relaxant properties.
Miren Ettcheto, Miren Ettcheto, Miren Ettcheto, Miren Ettcheto, Jordi Olloquequi, Elena Sánchez-López, Elena Sánchez-López, Elena Sánchez-López, Oriol Busquets, Oriol Busquets, Oriol Busquets, Oriol Busquets, Amanda Cano, Amanda Cano, Amanda Cano, Patricia Regina Manzine, Carlos Beas-Zarate, Rubén D. Castro-Torres, Maria Luisa García, Maria Luisa García, Maria Luisa García, Mónica Bulló, Mónica Bulló, Mónica Bulló, Carme Auladell, Carme Auladell, Carme Auladell, Jaume Folch, Jaume Folch, Antonio Camins, Antonio Camins, Antonio Camins, Antonio Camins   +32 more
doaj   +1 more source

Alcohol Withdrawal – Therapeutical Management in Surgical Patients with Upper Intestinal Bleeding [PDF]

, 2015
Psychological dependence involves a desire to use a drug to avoid the unpleasant withdrawal syndrome that results from cessation of exposure to it. Alcohol withdrawal syndrome is one of the most feared complications of alcohol addiction and sometimes can
Bogdan, Popescu, Cristian, Bălălău, Denisa, Cobani Oana, Gloria, Trambitasu, Negrei, Carolina, Valentin, Scăunașu Răzvan   +5 more
core   +3 more sources

Use of Benzodiazepines in Alzheimer’s Disease: A Systematic Review of Literature

International Journal of Neuropsychopharmacology, 2015
Background: Benzodiazepines are frequently prescribed in patients with Alzheimer’s disease. Unfortunately, studies evaluating their benefits and risks in these patients are limited.
M. Defrancesco, Josef Marksteiner, W. Wolfgang Fleischhacker, I. Blasko   +3 more
semanticscholar   +1 more source

Rapid and Simple Dispersive Liquid–Liquid Microextraction (DLLME) Sample Preparation for Propofol Analysis in Hair, Blood, and Urine by Gas Chromatography–Mass Spectrometry

Drug Testing and Analysis, EarlyView.
Development and validation of an extraction method based on dispersive liquid–liquid microextraction for the analysis by GC–MS of propofol in three different biological samples (blood, urine, and hair). The proposed method is very simple and rapid.
Sara Odoardi, Serena Mestria, Valeria Valentini, Giulia Biosa, Sabina Strano Rossi   +4 more
wiley   +1 more source