Results 181 to 190 of about 153,478 (337)

GRADE‐Based Clinical Practice Guidelines for Emergency Department Delirium Risk Stratification, Screening, and Brain Imaging in Older Patients With Suspected Delirium

open access: yesAcademic Emergency Medicine, EarlyView.
ABSTRACT Objectives This portion of the Geriatric Emergency Department (GED) Guidelines 2.0 focuses on delirium in the emergency department (ED). Methods A multidisciplinary group applied the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and develop recommendations related to ...
Sangil Lee   +13 more
wiley   +1 more source

Harm reduction approaches for the use of benzodiazepines: a scoping review. [PDF]

open access: yesHarm Reduct J
Morrison C   +4 more
europepmc   +1 more source

Drug Use After Emergency Department‐Initiated Injectable Buprenorphine: A Secondary Analysis of the ED‐INNOVATION Ancillary Safety and Feasibility Trial

open access: yesAcademic Emergency Medicine, EarlyView.
ABSTRACT Study Objective To characterize opioid and nonopioid drug use in the week following emergency department (ED)‐initiated extended‐release buprenorphine (XR‐BUP) treatment using both self‐reported data and urine drug screens (UDS). Methods This study uses data collected during a nonrandomized clinical trial of patients with untreated opioid use ...
Ethan Cowan   +10 more
wiley   +1 more source

Potential TMS biomarkers for GABAB receptor engagement in alcohol use disorder: A systematic review of existing evidence

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
This systematic review emphasizes the critical role of GABAB receptors (GABABR) in alcohol use disorder (AUD). While GABABR agonists enhance cortical inhibition, as measured by transcranial magnetic stimulation (TMS)‐based markers, alcohol consumption alters GABABR ‐dependent neurophysiological measures, suggesting GABABR dysfunction plays a key role ...
Chiara Montemitro   +4 more
wiley   +1 more source

Evaluation of glycine treatment for reducing alcohol craving and self‐administration in individuals with alcohol use disorder: A human laboratory trial

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
This RCT evaluated whether the glycine receptor (GlyR) agonist glycine reduces craving and alcohol intake in individuals with AUD. Despite a preclinical rationale for targeting the GlyR, these parameters were not reduced. Interestingly, glycine weakened the link between alcohol‐induced craving and self‐administration, and baseline glycine levels were ...
Yasmin Olsson   +3 more
wiley   +1 more source

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