Results 321 to 330 of about 207,949 (383)

Changes in cortical delta power during chronic invasive epilepsy monitoring

Epilepsia, EarlyView.
Abstract Objective Cortical delta band (1–4 Hz) activity is considered a biomarker for states of altered consciousness, with increased delta power observed during anesthesia, sleep, coma, and delirium. The current study sought to characterize delta power following electrode implantation with respect to patient demographics and clinical characteristics ...
Emily R. Dappen, Bryan M. Krause, Rashmi N. Mueller, Matthew I. Banks, Kirill V. Nourski   +4 more
wiley   +1 more source

The changing role of substances: trends, characteristics of individuals and prior healthcare utilization among individuals with accidental substance-related toxicity deaths in Ontario Canada. [PDF]

PLoS One
Ledlie S, Holton A, Leece P, Hamzat B, Yang J, Kolla G, Bozinoff N, Boyd R, Franklyn M, Smoke A, Newcombe P, Gomes T.   +11 more
europepmc   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher, Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source

"Pharmacological management of acute agitation in psychiatric patients: an umbrella review". [PDF]

BMC Psychiatry
Uribe ES, Rodríguez CAB, Juárez MEN, Juárez SM, Lucio RH, Guzmán KER, Carrillo LCL.   +6 more
europepmc   +1 more source

Potentially inappropriate medication and its associated factors in older people living in nursing homes: a cross-sectional study. [PDF]

PeerJ
Goutan-Roura E, Carneiro GO, Moreira FSM, Masó-Aguado M, Moreno-Martin P, Minobes-Molina E, Skelton DA, Jerez-Roig J.   +7 more
europepmc   +1 more source

To: Delirium and sleep quality in the intensive care unit: the role of melatonin. [PDF]

Crit Care Sci
Finsterer J, Mehri S.
europepmc   +1 more source

Effective synthesis of benzodiazepine sulfonamide-based MGAT2 inhibitors and evaluation of their antitumor activity. [PDF]

RSC Adv
Zhang Y, Li Y, Liu X, Wang Y, Zheng H, Zhou D.   +5 more
europepmc   +1 more source