Results 51 to 60 of about 1,987 (185)

Asymmetric Catalytic Hydrogenation toward a Value‐Added Chiral Building Block: Optically Active γ‐Butyrolactone Scaffold from Renewable and Synthetic Derived Feedstocks

European Journal of Organic Chemistry, Volume 29, Issue 3, January 22, 2026.
This brief compendium summarizes the most successful asymmetric hydrogenation strategies for the preparation of chiral monocyclic γ‐lactone derivatives from keto acids and keto esters, with emphasis on their relevance for large‐scale production and high enatioselectivities. This article provides a brief compendium on the production of chiral monocyclic
Marta Feliz, Maria J. Sabater
wiley   +1 more source

6-Nitro-1,3-benzodioxole-4-carbaldehyde

Acta Crystallographica Section E Structure Reports Online, 2006
The title compound, C8H5NO5, consists of a cyclic diether (1,3-dioxalene) fused to 3-nitro­benzaldehyde. In the crystal structure, symmetry-related mol­ecules are linked by C—H⋯O hydrogen bonds, forming a sheet-like structure parallel to the ab plane. These sheets are further linked by C—H⋯O hydrogen bonds, forming a three-dimensional network.
Mukhtiar Hussain, Saqib Ali, Muhammad Altaf, Helen Stoeckli-Evans   +3 more
openaire   +1 more source

(S)-(−)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
In the chiral title compound, C(38)H(28)O(4)P(2), the intra-molecular P⋯P separation is 3.671 (2) Å and the dihedral angle between the two benzene rings in the biphenyl unit is 77.9 (2)°.
Jian, Ling-Yan, He, Xiao-Jing, Sun, Ya-Xin, Jiang, Qing-Hua, Zhu, Xu   +4 more
openaire   +2 more sources

Antioxidant Testing and Identification of Bioactive Compounds in Ethanol Extract of Propolis from Various Locations in Indonesia using LCMS-QTOF [PDF]

Propolis produced by Trigona sp. stingless bees contains various bioactive substances including alkaloids, flavonoids, polyphenols, saponins, steroids, and terpenoids.
Alawiyah, Hanis, Marom, Muhamad Fathul, Mulyati, Ade Heri, Warnasih, Siti   +3 more
core   +2 more sources

Small‐Molecule Sarco/Endoplasmic Reticulum Ca2+‐ATPase Activators Reverse Methylglyoxal‐Induced Inhibition through Nonantioxidant Mechanisms

ChemMedChem, Volume 21, Issue 1, January 2026.
Endoplasmic reticulum (ER) Ca2+ dysregulation drives β‐cell dysfunction under diabetic stressors like methylglyoxal, which inhibits the sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) pump through oxidative modifications. We show that synthetic SERCA activators restore pump activity after methylglyoxal‐induced damage.
Carlos Cruz‐Cortés, Silvia Micháliková, Petronela Rezbáriková, L. Michel Espinoza‐Fonseca, Jana Viskupičová   +4 more
wiley   +1 more source

Cooperative Photocatalysis of 9,10‐Phenanthrenequinone and Sn(OTf)2 for Direct Mannich Reaction of Ethers via Hydrogen Atom Transfer Pathway

Advanced Synthesis &Catalysis, Volume 367, Issue 23, December 11, 2025.
A dual photocatalytic system of o‐PQ and Sn(OTf)2 enables visible light‐induced Mannich‐type addition of ethers to nitrones via Csp³–H activation. This oxidant‐free method offers broad scope and good yields. Mechanistic studies suggest that a photoexcited o‐PQ–Sn(II) complex mediates hydrogen atom transfer to form α‐oxy radicals for nitrone addition. A
Pradip Ramdas Thorve, Hun Young Kim, Kyungsoo Oh   +2 more
wiley   +1 more source

2,2-Dimethyl-1,3-benzodioxol-4-ylN-methylcarbamate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
In the title compound, C(11)H(13)NO(4), the two fused rings are almost coplanar, making a dihedral angle of 3.02 (8)°. In the crystal, chains are formed parallel to [010] through N-H⋯O hydrogen bonds between the amine and carbonyl groups.
openaire   +3 more sources

Investigation of in Silico Modelling to Predict the Human Health Effects of Cosmetics Ingredients [PDF]

Animal experiments have been the standard method to assess the safety of chemicals used in cosmetic products for decades. However, public opinion has continued to demand that in vivo hazard identification methods conducted on animals are replaced with ...
Aljallal, M
core   +1 more source

A Radical‐Based, Transition Metal‐Free Approach for Diaryl Ketone Synthesis

ChemSusChem, Volume 18, Issue 21, Novemebr 4, 2025.
A sustainable and scalable one‐pot route to diverse diaryl ketones is described, proceeding via a distinctive radical process between aryl halides and benzonitriles, initiated by KOtBu/DMA and driven by air as the sole oxidant. Free from transition metals, peroxides, and carbon monoxide, this catalyst‐free and selective method exhibits broad functional
Dongjie Wang, Jordan Garo, Yinpeng Wang, Jean‐Marc Sotiropoulos, Marc Taillefer   +4 more
wiley   +1 more source

Synthesis and Anticancer Potential of New Benzimidazole Theranostic

ChemistryOpen, Volume 14, Issue 11, November 2025.
Recent advances have highlighted benzimidazole's importance in anticancer drug discovery. A novel series of benzimidazole analogs is designed and synthesized, with V7 showing broad anticancer activity and selectivity, possibly linked to SIRT2 inhibition.
Sahani Sandalima Uthumange, Muhammad Azri Faiz bin Abdul Zaki, Keng Yoon Yeong   +2 more
wiley   +1 more source