Depression Symptoms in Patients with Cystic Fibrosis Fluctuate at Baseline and Improve with Elexacaftor/Tezacaftor/Ivacaftor Therapy. [PDF]
Piehler L +5 more
europepmc +1 more source
Upregulation of Sox2 Following Saracatinib Treatment Contributes to a Resistant Phenotype in Colorectal Cancer Cells under Growth Factor-Supplemented Conditions. [PDF]
Yoon C, Na E, Choi MJ, Yoon SP.
europepmc +1 more source
Obstetric and Neonatal Outcomes in Pregnancies From a Dedicated Cystic Fibrosis-Maternal Health Service: A Retrospective Study. [PDF]
Scott R +12 more
europepmc +1 more source
Non-tuberculous mycobacterial infection in cystic fibrosis before and after initiation of elexacaftor/tezacaftor/ivacaftor: now is not the time to lower the guard. [PDF]
Evans IES +8 more
europepmc +1 more source
Cross-species metabolic characterization of eutylone and mechanism-based inhibition of CYP2D6 and CYP2B6 with drug interaction implications. [PDF]
Lee MS +7 more
europepmc +1 more source
The validated French CFAbd-Score reveals a lower burden of gastrointestinal symptoms in patients on Elexacaftor/Tezacaftor/Ivacaftor. [PDF]
Sermet-Gaudelus I +13 more
europepmc +1 more source
Respiratory Oscillometry and Multimodal Lung Function Assessment of Elexacaftor/Tezacaftor/Ivacaftor Response in Children and Young Adults With Cystic Fibrosis. [PDF]
Kogias C +8 more
europepmc +1 more source
Mechanism of the metabolism of 1,3-benzodioxoles to carbon monoxide
Biochemical Pharmacology, 1984Carbon monoxide is a minor product formed during the cytochrome P-450-catalyzed oxidation of 1,3-benzodioxoles. Studies with [2-13C]methylene 1,3-benzodioxoles established that the methylenic carbon of the 1,3-benzodioxole ring is the source of the carbon atom in the carbon monoxide, and an isotope effect of 1.7 to 2.0 was observed with [2-2H2 ...
M W Anders, Christopher F Wilkinson
exaly +3 more sources

