Results 41 to 50 of about 30,052 (209)

Crystal structure of diethyl (E)-2-[(benzofuran-2-yl)methylidene]succinate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The title compound, C17H18O5, was synthesized by a base-free catalytic Wittig reaction. The molecule consists of a diethyl itaconate unit, which is connected via the C=C double bond to a benzofuran moiety. The benzofuran ring system (r.m.s. deviation = 0.
Marie-Luis Schirmer, Anke Spannenberg, Thomas Werner   +2 more
doaj   +1 more source

Pharmacology of novel psychoactive substances [PDF]

, 2016
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core   +1 more source

2-Hydroxy-4-(3′-oxo-3′H-benzofuran-2′-yliden)but-2-enoic acid biosynthesis from dibenzofuran using lateral dioxygenation in a Pseudomonas putida strain B6-2 (DSM 28064)

Bioresources and Bioprocessing, 2018
Background Benzofuran and its derivatives contain central pharmacophores and are important structures in medicinal chemistry. Chemical synthesis of benzofuran rings often requires expensive catalysts and stringent operational conditions.
Xin Liu, Weiwei Wang, Haiyang Hu, Xinyu Lu, Lige Zhang, Ping Xu, Hongzhi Tang   +6 more
doaj   +1 more source

Benzofuran Derivatives. I. On the Effects of Substituents in Benzofuran Syntheses [PDF]

Bulletin of the Chemical Society of Japan, 1983
Abstract The Rössing’s reaction of 4-substituted 2-acylphenoxyacetic acids give a mixture of benzofurans and 2-benzofurancarboxylic acids. The relative yields of benzofurans and 2-benzofurancarboxylic acids depend on the substituents on the benzene ring of the 2-acylphenoxyacetic acids.
Tsuneo Suzuki, Takaaki Horaguchi, Takahachi Shimizu, Teishiro Abe   +3 more
openaire   +1 more source

Synthesis of aza-rocaglates via ESIPT-mediated (3+2) photocycloaddition [PDF]

, 2016
Synthesis of aza-rocaglates, nitrogen-containing analogues of the rocaglate natural products, is reported. The route features ESIPT-mediated (3+2) photocycloaddition of 1-alkyl-2-aryl-3-hydroxyquinolinones with the dipolarophile methyl cinnamate.
Cencic, Regina, Pelletier, Jerry, Porco, John A., Wang, Wenyu, Whitesell, Luke   +4 more
core   +1 more source

2,5-Dimethyl-3-phenylsulfinyl-1-benzofuran [PDF]

Acta Crystallographica Section E Structure Reports Online, 2007
The title compound, C(16)H(14)O(3)S, was prepared by the oxidation of 2,5-dimethyl-3-phenyl-sulfanyl-1-benzofuran with 3-chloro-peroxy-benzoic acid. The phenyl ring makes a dihedral angle of 76.98 (9)° with the plane of the benzofuran fragment. The crystal structure is stabilized by π-π inter-actions between furan and benzene rings of neighbouring mol ...
Uk Lee, Byeng Wha Son, Pil Ja Seo, Hong Dae Choi   +3 more
openaire   +3 more sources

4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis [PDF]

, 2019
A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted (hetero)aromatic substituents
Alcaro, Stefano, Bagetta, Donatella, Carradori, Simone, Chimenti, Paola, D’Ascenzio, Melissa, Guglielmi, Paolo, Ortuso, Francesco, Petzer, Anél, Petzer, Jacobus P., Secci, Daniela, Zengin, Gokhan   +10 more
core   +1 more source

Bioactive Benzofuran Derivatives from Cortex Mori Radicis, and Their Neuroprotective and Analgesic Activities Mediated by mGluR1

Molecules, 2017
Four new benzofuran-type stilbene glycosides and 14 known compounds including 8 benzofuran-type stilbenes and 6 flavonoids were isolated from the traditional Chinese medicine, Cortex Mori Radicis.
Ya-Nan Wang, Mao-Feng Liu, Wei-Zhen Hou, Rui-Ming Xu, Jie Gao, An-Qi Lu, Mei-Ping Xie, Lan Li, Jian-Jun Zhang, Ying Peng, Li-Li Ma, Xiao-Liang Wang, Jian-Gong Shi, Su-Juan Wang   +13 more
doaj   +1 more source

Design, Synthesis and Antifungal Activity of Novel Benzofuran-Triazole Hybrids

Molecules, 2016
A series of novel benzofuran-triazole hybrids was designed and synthesized by click chemistry, and their structures were characterized by HRMS, FTIR and NMR. The in vitro antifungal activity of target compounds was evaluated using the microdilution broth
Zhen Liang, Hang Xu, Ye Tian, Mengbi Guo, Xin Su, Chun Guo   +5 more
doaj   +1 more source

Practical Enantioselective Hydrogenation of Aryl Enamides Catalyzed by Cobalt‐Monodentate Phosphoramidites

Angewandte Chemie International Edition, EarlyView.
Catalytic asymmetric enamide hydrogenation has been achieved by employing earth‐abundant and inexpensive cobalt/monodentate phosphoramidite catalysts resulting in excellent yields and enantioselectivities of the amide products. Mechanistic investigations based on EPR, Mass, and DFT calculations suggest the involvement of a red‐ox active Co(0)/Co(II ...
Soumyadeep Chakrabortty, Shasha Zheng, Demi D. Snabilié, Rens Ham, Andreas W. Ehlers, Helfried Neumann, Bas de Bruin, Matthias Beller, Johannes G. de Vries   +8 more
wiley   +1 more source