Results 131 to 140 of about 4,414 (202)

Total synthesis of natural products based on hydrogenation of aromatic rings. [PDF]

Beilstein J Org Chem
Wu H, Qi X.
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Correction to "Photochemical Deracemization of 4,7-Diaza-1-isoindolinones by Unidirectional Hydrogen Atom Shuttling". [PDF]

J Am Chem Soc
Freund P, Pauls M, Babushkina D, Pickl T, Bannwarth C, Bach T.   +5 more
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Exploring Dimethyl Carbonate as a Green and Efficient Solvent for Highly Regioselective Iodination of Arylboronic Acids. [PDF]

ACS Omega
Santarsiere A, Loriso M, Ambrosio F, Chiummiento L.   +3 more
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Regioselective Synthesis of Benzofuranones and Benzofurans

The Journal of Organic Chemistry, 2021
Reaction of 3-hydroxy-2-pyrones with nitroalkenes bearing ester groups gives benzofuranones. The reaction allows regioselective preparation of the benzofuranones with programmable substitution at any position. Complex substitution patterns are readily created. The substituted benzofuranones can be converted to substituted benzofurans.
Xiaojie Zhang, Christopher M. Beaudry
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Benzofuran derivatives. Part 3 On the reactivities of the intermediates in benzofuran synthesis

Journal of Heterocyclic Chemistry, 1987
Abstract3‐Methyl‐5‐nitrobenzofuran (2) and 3‐methyl‐5‐nitrobenzofuran‐2‐carboxylic acid (3) were obtained by heating 2‐acetyl‐4‐nitrophenoxyacetic acid (1) with various bases in acetic anhydride. It appeared that 3‐hydroxy‐3‐methyl‐5‐nitro‐2,3‐dihydrobenzofuran‐2‐carboxylic acid (4) was the intermediate in the benzofuran synthesis.
Takaaki Horaguchi, Shinichi Matsuda, Kiyoshi Tanemura, Tsuneo Suzuki   +3 more
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Bioactive Benzofuran derivatives: A review

European Journal of Medicinal Chemistry, 2015
In nature's collection of biologically active heterocycles, benzofuran derivatives constitute a major group. The broad spectrum of pharmacological activity in individual benzofurans indicates that this series of compounds is of an undoubted interest.
Hena, Khanam, , Shamsuzzaman
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Biological and medicinal significance of benzofuran

European Journal of Medicinal Chemistry, 2015
This article emphasizes on the importance of benzofuran as a biologically relevant heterocycle. It covers most of the physiologically as well as medicinally important compounds containing benzofuran rings. This article also covers clinically approved drugs containing benzofuran scaffold.
Nevagi, Reshma J., Dighe, Santosh N., Dighe, Satish N.   +2 more
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Benzofuran based PDE4 inhibitors

Bioorganic & Medicinal Chemistry, 1999
Replacement of the 3,4-dialkoxyphenyl substructure common to a number of PDE4 inhibitors with a 2-alkyl-7-methoxybenzofuran unit is described. This substitution can result in either enhancement or substantial reductions in PDE4 inhibitory activity depending on the system to which it is applied.
D G, McGarry, J R, Regan, F A, Volz, C, Hulme, K J, Moriarty, S W, Djuric, J E, Souness, B E, Miller, J J, Travis, D M, Sweeney   +9 more
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