Results 11 to 20 of about 8,220 (213)

Insect Antifeedant Benzofurans from Pericallis Species

Molecules, 2023
In this work, we have studied the benzofurans of Pericallis echinata (aerial parts and transformed roots), P. steetzii (aerial parts and transformed roots), P. lanata (aerial parts), and P. murrayi (aerial parts and roots).
Carmen E. Díaz, Braulio M. Fraga, Adriana G. Portero, Iván Brito, Carmen López-Balboa, Liliana Ruiz-Vásquez, Azucena González-Coloma   +6 more
doaj   +1 more source

INVESTIGATION OF 3-BENZOYLBENZOFURANS AND THEIR METHYLATED AND PYRAZOLE DERIVATIVES FOR POTENTIAL INHIBITION OF HIV-1 REPLICATION

International Journal of Infectious Diseases, 2023
Intro: Approximately 38.4 million people were living with HIV in 2021, with 650 000 AIDS-related deaths reported globally (UNAIDS updates 2022). Antiretrovirals are the combination of drugs against multiple stages of infections and are the most effective
S. Khuzwayo, M. Selepe, D. Meyer, N. Gama   +3 more
doaj   +1 more source

Protein Binding of Benzofuran Derivatives: A CD Spectroscopic and In Silico Comparative Study of the Effects of 4-Nitrophenyl Functionalized Benzofurans and Benzodifurans on BSA Protein Structure

Biomolecules, 2022
Benzofuran derivatives are synthetic compounds that are finding an increasing interest in the scientific community not only as building blocks for the realization of new materials, but also as potential drugs thanks to their ability to interact with ...
Pasqualina Liana Scognamiglio, Caterina Vicidomini, Francesco Fontanella, Claudio De Stefano, Rosanna Palumbo, Giovanni N. Roviello   +5 more
doaj   +1 more source

An index of fatal toxicity for new psychoactive substances [PDF]

, 2018
The final, definitive version of this paper has been published in Journal of Psychopharmacology, February 2018, published by SAGE Publishing, All rights reserved.An index of fatal toxicity for new psychoactive substances has been developed based solely ...
Corkery, John, King, L.A.
core   +2 more sources

Pharmacological profile of novel psychoactive benzofurans [PDF]

, 2015
Benzofurans are newly used psychoactive substances, but their pharmacology is unknown. The aim of the present study was to pharmacologically characterize benzofurans in vitro.; We assessed the effects of the benzofurans 5-APB, 5-APDB, 6-APB, 6-APDB, 4 ...
Hoener, Marius C., Kopf, Simone, Liechti, Matthias E., Rickli, Anna   +3 more
core   +1 more source

Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
In the current work, a hybridisation strategy was adopted between the privileged building blocks, benzofuran and piperazine, with the aim of designing novel CDK2 type II inhibitors.
Wagdy M. Eldehna, Raed M. Maklad, Hadia Almahli, Tarfah Al-Warhi, Eslam B. Elkaeed, Mohammed A. S. Abourehab, Hatem A. Abdel-Aziz, Ahmed M. El Kerdawy   +7 more
doaj   +1 more source

Pharmacology of novel psychoactive substances [PDF]

, 2016
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core   +1 more source

Sonogashira/N-acyliminium ion aromatic π-cyclisation processes: access to tetra- and pentacyclic lactams [PDF]

, 2008
Application of the Sonogashira reaction of N-alkynylimides with 2-iodophenol or 2-iodo-N-tosylaniline affords 2-(N-alkylimino)-benzofurans and indoles in good yield.
Grigg, R., Sridharan, V., Sykes, D.A.
core   +1 more source

A Recyclable Palladium-Catalyzed Synthesis of 2-Methylene-2,3-Dihydrobenzofuran-3-ols by Cycloisomerization of 2-(1-Hydroxyprop-2-ynyl)phenols in Ionic Liquids

Molecules, 2013
A recyclable palladium-catalyzed synthesis of 2-methylene-2,3-dihydrobenzofuran-3-ols 2 by heterocyclization of 2-(1-hydroxyprop-2-ynyl)phenols 1 in an ionic liquid medium (BmimBF4) is presented.
Bartolo Gabriele, Raffaella Mancuso
doaj   +1 more source

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Pursuing on our efforts toward searching for efficient hCA IX and hCA XII inhibitors, herein we report the design and synthesis of new sets of benzofuran-based sulphonamides (4a,b, 5a,b, 9a–c, and 10a–d), featuring the zinc anchoring benzenesulfonamide ...
Mohamed A. Abdelrahman, Wagdy M. Eldehna, Alessio Nocentini, Hany S. Ibrahim, Hadia Almahli, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri, Claudiu T. Supuran   +7 more
doaj   +1 more source