Results 31 to 40 of about 6,146 (188)

Synthesis of New Derivatives of Benzofuran as Potential Anticancer Agents

Molecules, 2019
The results of our previous research indicated that some derivatives of benzofurans, particularly halogeno-derivatives, are selectively toxic towards human leukemia cells.
Mariola Napiórkowska, Marcin Cieślak, Julia Kaźmierczak-Barańska, Karolina Królewska-Golińska, Barbara Nawrot   +4 more
doaj   +1 more source

2,3-Diaroyl benzofurans from arynes: sequential synthesis of 2-aroyl benzofurans followed by benzoylation

, 2018
A cascade synthetic strategy for the direct synthesis of 2-aroyl benzofurans from aryne precursors has been described. The synthesized 2-aroyl benzofurans were further benzoylated for the synthesis of 2,3-diaroyl benzofurans.
Babulal Das, Pranjal Gogoi, Kashmiri Neog   +2 more
core   +1 more source

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Sulfur-containing benzofurans and α-pyrones from the mangrove-derived fungus Talaromyces sp. WHUF0341

Frontiers in Marine Science, 2022
Two new sulfur-containing benzofurans, talarobenzofurans A and B (1 and 2), one new benzofuran talarobenzofuran C (3) and two new α-pyrones talaropyrones A and B (5 and 6), along with five known compounds eurothiocin A (4), nodulisporipyrone A (7 ...
Ruohan Zhang, Ruohan Zhang, Jinxin Zhang, Jinxin Zhang, Ruiyun Huo, Ruiyun Huo, Yaxin Xue, Kui Hong, Ling Liu, Ling Liu   +9 more
doaj   +1 more source

Deprotonation and Alkylation of Weakly Acidic C(sp3)─H Bonds Through In Situ Generation of a Strong Hydride Base From 1,1,3,3‐Tetramethyldisiloxane and Potassium tert‐Butoxide

Angewandte Chemie, EarlyView.
The use of 1,1,3,3‐tetramethyldisiloxane (TMDSO) and potassium tert‐butoxide enables direct alkylation of weakly acidic carbon–hydrogen bonds with alkyl halides. Experimental and computational studies support the formation of a substrate‐associated hydride‐like base, providing a single‐step alternative to the classical deprotonation and electrophile ...
Piers St. Onge, Brandon White, Han Yao, Travis Dudding, Stephen G. Newman   +4 more
wiley   +2 more sources

Preparation of Functional Benzofurans, Benzothiophenes, and Indoles Using Ester, Thioester, and Amide via Intramolecular Wittig Reactions

, 2016
Preparation of new types of highly functional benzofurans, benzothiophenes, and indoles is realized via intramolecular Wittig reactions with the corresponding ester, thioester, and amide functionalities.
Yeong-Jiunn Jang (2096290), Wenwei Lin (278782), Siang-en Syu (2195077), Yu-Ting Lee (2003923)   +3 more
core   +5 more sources

From Berzelius to Hyperspace: Previously Unrecognized Network of Reactivity in Textbook Brominations

Angewandte Chemie, EarlyView.
Robotic scans across multidimensional condition spaces of classic bromination reactions uncover regions of previously unrecognized reactivity, yielding new major products and novel substitution patterns. Correlation and anticorrelation analyses of product distributions across these hyperspaces enable reconstruction of the underlying mechanistic ...
Yankai Jia, Wai‐Shing Wong, Yasemin Bilgi‐Gadina, Louis P. J.‐L. Gadina, King‐Lam Kwong, Yanqiu Jiang, Nikolaos Vagkidis, Benito Marazzi, Peter R. Schreiner, Bartosz A. Grzybowski   +9 more
wiley   +2 more sources

Preparation of Substituted Hydroquinones and Benzofurans from 1,4-Quinone Monoketals

, 2006
International audienceAn easy procedure for the preparation of 2-substituted hydroquinones, by addition of organolithium or organomagnesium compounds to 1,4-quinone monoketals followed by acid-catalyzed dienone-phenol type rearrangement, is described ...
Salom-Roig, Xavier, Salom-Roig, Xavier,, Xavier J. Salom‐Roig, Renaud, Philippe, Philippe Renaud   +4 more
core   +1 more source

Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Proceedings, 2019
Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]
Marole Maria Maluleka, Malose Jack Mphahlele   +1 more
doaj   +1 more source

Synthesis of 2-(3'-pyridyl)-Y-pyrano-Benzofurans and 3'-hydroxy-2'-(3''-pyridyl)-Y-pyrano-Benzofurans

, 1980
Department of Chemistry, Marathwada University, Aurangabad-431 001, India Manuscript received 12 January 1980, accepted 9 July 1980 A few 2'-(3"-pyridyl)-Y-pyrano-benzofurans (IVa-c) and 3'-hydroxy-2'-(3"-pyridy1)- Y-pyrano-benzofurans (Va-c) were ...
K. A. THAKAR, R. C. JOSHI
core   +1 more source