Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Pursuing on our efforts toward searching for efficient hCA IX and hCA XII inhibitors, herein we report the design and synthesis of new sets of benzofuran-based sulphonamides (4a,b, 5a,b, 9a–c, and 10a–d), featuring the zinc anchoring benzenesulfonamide ...
Mohamed A. Abdelrahman +7 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 In the current work, a hybridisation strategy was adopted between the privileged building blocks, benzofuran and piperazine, with the aim of designing novel CDK2 type II inhibitors.
Wagdy M. Eldehna +7 more
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Pharmacology of novel psychoactive substances [PDF]
, 2016 This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
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Molecules, 2013 A recyclable palladium-catalyzed synthesis of 2-methylene-2,3-dihydrobenzofuran-3-ols 2 by heterocyclization of 2-(1-hydroxyprop-2-ynyl)phenols 1 in an ionic liquid medium (BmimBF4) is presented.
Bartolo Gabriele, Raffaella Mancuso
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Highlighting the effects of co‐eluting interferences on compound specific stable isotope analysis of polycyclic aromatic hydrocarbons using comprehensive two‐dimensional gas chromatography [PDF]
, 2014 Accuracy is the most important issue when carrying out compound specific stable isotope analysis of polycyclic aromatic hydrocarbons extracted from complex samples.
Blessing +16 more
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Nickel–NHC-Catalyzed Cross-Coupling of 2-Methylsulfanylbenzofurans with Alkyl Grignard Reagents [PDF]
, 2014 NiCl2(PPh3)(IPr) catalyzes cross-coupling reactions of 2-methylsulfanylbenzofurans with alkyl Grignard reagents. Other nickel complexes such as NiCl2(dppe) failed to catalyze the same reaction. The alkylation is applicable to the synthesis of a couple of
Baralle, Alexandre +5 more
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The phytochemical composition of Melia volkensii and its potential for insect pest management [PDF]
, 2020 Due to potential health and environmental risks of synthetic pesticides, coupled with their non-selectivity and pest resistance, there has been increasing demand for safer and biodegradable alternatives for insect pest management.
Backx, Simon +9 more
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Synthesis of functionalized benzofurans by iodocyclization reaction of alkynylanisoles
Orbital: The Electronic Journal of Chemistry, 2012 Benzofurans are important synthetic building blocks present in a high number of biologically active natural products, pursuing several medicinal properties. In this context, there is an increasing interest in developing efficient syntheses for this class
Carlise Frota, Cristiano Raminelli
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Combined in vitro and in silico approaches to the assessment of stimulant properties of novel psychoactive substances – The case of the benzofuran 5-MAPB [PDF]
, 2016 Novel psychoactive substances (NPS) are increasingly prevalent world-wide although their pharmacological characteristics are largely unknown; those with stimulant properties, due to interactions with the dopamine transporter (DAT), have addictive ...
Beuming +49 more
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Antipoliovirus activity of the organic extract of Eupatorium buniifolium: isolation of euparin as an active compound [PDF]
, 2013 The antiviral activity of the organic extract (OE) of Eupatorium buniifolium against poliovirus type 1 was determined by in vitro assays with an effective concentration 50 (EC50) of 23.3 ± 3.3 µg/mL.
Campos, Rodolfo Hector +4 more
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