A recyclable palladium-catalyzed synthesis of 2-methylene-2,3-dihydrobenzofuran-3-ols 2 by heterocyclization of 2-(1-hydroxyprop-2-ynyl)phenols 1 in an ionic liquid medium (BmimBF4) is presented.
Bartolo Gabriele, Raffaella Mancuso
doaj +1 more source
Pharmacology of novel psychoactive substances [PDF]
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
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Nickel–NHC-Catalyzed Cross-Coupling of 2-Methylsulfanylbenzofurans with Alkyl Grignard Reagents [PDF]
NiCl2(PPh3)(IPr) catalyzes cross-coupling reactions of 2-methylsulfanylbenzofurans with alkyl Grignard reagents. Other nickel complexes such as NiCl2(dppe) failed to catalyze the same reaction. The alkylation is applicable to the synthesis of a couple of
Baralle, Alexandre +5 more
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Benzofuran derivatives and the thyroid [PDF]
SummaryAmiodarone and dronedarone are two clinically important benzofuran derivatives. Amiodarone has been used widely for treating resistant tachyarrhythmias in the past three decades. However amiodarone and its main metabolically active metabolite desethylamiodarone can adversely affect many organs, including the thyroid gland.
T S, Han +2 more
openaire +2 more sources
Zinc–gold cooperative catalysis for the direct alkynylation of benzofurans
The direct alkynylation of benzofurans was achieved for the first time using the hypervalent iodine reagent 1-[(triisopropylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one (TIPS-EBX) based on the cooperative effect between a gold catalyst and a zinc Lewis acid.
Yifan Li, Jérôme Waser
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Synthesis of functionalized benzofurans by iodocyclization reaction of alkynylanisoles
Benzofurans are important synthetic building blocks present in a high number of biologically active natural products, pursuing several medicinal properties. In this context, there is an increasing interest in developing efficient syntheses for this class
Carlise Frota, Cristiano Raminelli
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Processing waste printed circuit boards for material recovery [PDF]
PURPOSE We have investigated the use of pyrolysis for the processing of waste printed circuit boards (PCBs). The aim was to make the process of separating the organic, metallic, and glass fibre fractions of PCBs much easier and therefore make ...
Hall, W.J., Williams, P.T
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The phytochemical composition of Melia volkensii and its potential for insect pest management [PDF]
Due to potential health and environmental risks of synthetic pesticides, coupled with their non-selectivity and pest resistance, there has been increasing demand for safer and biodegradable alternatives for insect pest management.
Backx, Simon +9 more
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2-Benzyl-benzofurans from the tubers of Ophiopogon japonicus [PDF]
Additional file 1.
Dongho Lee +6 more
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Combined in vitro and in silico approaches to the assessment of stimulant properties of novel psychoactive substances – The case of the benzofuran 5-MAPB [PDF]
Novel psychoactive substances (NPS) are increasingly prevalent world-wide although their pharmacological characteristics are largely unknown; those with stimulant properties, due to interactions with the dopamine transporter (DAT), have addictive ...
Beuming +49 more
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