Results 11 to 20 of about 4,414 (202)

Elicitation of Stilbenes and Benzofuran Derivatives in Hairy Root Cultures of White Mulberry (Morus alba)

Plants, 2022
Stilbene and benzofuran derivatives isolated from the root of white mulberry (Morus alba) have shown various biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties. The objectives of this study were to develop hairy
Lingling Fang, Amit Raj Sharma, Chineche Aniemena, Krystian Roedel, Florence Henry, Philippe Moussou, Anita Samuga, Fabricio Medina-Bolivar   +7 more
doaj   +1 more source

Insect Antifeedant Benzofurans from Pericallis Species

Molecules, 2023
In this work, we have studied the benzofurans of Pericallis echinata (aerial parts and transformed roots), P. steetzii (aerial parts and transformed roots), P. lanata (aerial parts), and P. murrayi (aerial parts and roots).
Carmen E. Díaz, Braulio M. Fraga, Adriana G. Portero, Iván Brito, Carmen López-Balboa, Liliana Ruiz-Vásquez, Azucena González-Coloma   +6 more
doaj   +1 more source

INVESTIGATION OF 3-BENZOYLBENZOFURANS AND THEIR METHYLATED AND PYRAZOLE DERIVATIVES FOR POTENTIAL INHIBITION OF HIV-1 REPLICATION

International Journal of Infectious Diseases, 2023
Intro: Approximately 38.4 million people were living with HIV in 2021, with 650 000 AIDS-related deaths reported globally (UNAIDS updates 2022). Antiretrovirals are the combination of drugs against multiple stages of infections and are the most effective
S. Khuzwayo, M. Selepe, D. Meyer, N. Gama   +3 more
doaj   +1 more source

Protein Binding of Benzofuran Derivatives: A CD Spectroscopic and In Silico Comparative Study of the Effects of 4-Nitrophenyl Functionalized Benzofurans and Benzodifurans on BSA Protein Structure

Biomolecules, 2022
Benzofuran derivatives are synthetic compounds that are finding an increasing interest in the scientific community not only as building blocks for the realization of new materials, but also as potential drugs thanks to their ability to interact with ...
Pasqualina Liana Scognamiglio, Caterina Vicidomini, Francesco Fontanella, Claudio De Stefano, Rosanna Palumbo, Giovanni N. Roviello   +5 more
doaj   +1 more source

Benzofuran derivatives and the thyroid [PDF]

Clinical Endocrinology, 2008
SummaryAmiodarone and dronedarone are two clinically important benzofuran derivatives. Amiodarone has been used widely for treating resistant tachyarrhythmias in the past three decades. However amiodarone and its main metabolically active metabolite desethylamiodarone can adversely affect many organs, including the thyroid gland.
T S, Han, G R, Williams, M P J, Vanderpump   +2 more
openaire   +2 more sources

A Recyclable Palladium-Catalyzed Synthesis of 2-Methylene-2,3-Dihydrobenzofuran-3-ols by Cycloisomerization of 2-(1-Hydroxyprop-2-ynyl)phenols in Ionic Liquids

Molecules, 2013
A recyclable palladium-catalyzed synthesis of 2-methylene-2,3-dihydrobenzofuran-3-ols 2 by heterocyclization of 2-(1-hydroxyprop-2-ynyl)phenols 1 in an ionic liquid medium (BmimBF4) is presented.
Bartolo Gabriele, Raffaella Mancuso
doaj   +1 more source

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Pursuing on our efforts toward searching for efficient hCA IX and hCA XII inhibitors, herein we report the design and synthesis of new sets of benzofuran-based sulphonamides (4a,b, 5a,b, 9a–c, and 10a–d), featuring the zinc anchoring benzenesulfonamide ...
Mohamed A. Abdelrahman, Wagdy M. Eldehna, Alessio Nocentini, Hany S. Ibrahim, Hadia Almahli, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri, Claudiu T. Supuran   +7 more
doaj   +1 more source

Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
In the current work, a hybridisation strategy was adopted between the privileged building blocks, benzofuran and piperazine, with the aim of designing novel CDK2 type II inhibitors.
Wagdy M. Eldehna, Raed M. Maklad, Hadia Almahli, Tarfah Al-Warhi, Eslam B. Elkaeed, Mohammed A. S. Abourehab, Hatem A. Abdel-Aziz, Ahmed M. El Kerdawy   +7 more
doaj   +1 more source

Synthesis of functionalized benzofurans by iodocyclization reaction of alkynylanisoles

Orbital: The Electronic Journal of Chemistry, 2012
Benzofurans are important synthetic building blocks present in a high number of biologically active natural products, pursuing several medicinal properties. In this context, there is an increasing interest in developing efficient syntheses for this class
Carlise Frota, Cristiano Raminelli
doaj   +1 more source

One-Step Regioselective Synthesis of Benzofurans from Phenols and α-Haloketones

Molecules, 2019
Reported here is the direct synthesis of naphthofurans and benzofurans from readily available phenols and α-haloketones promoted by titanium tetrachloride which combines Friedel−Crafts-like alkylation and intramolecular cyclodehydration into ...
Bingqiao Wang, Qiu Zhang, Juan Luo, Zongjie Gan, Wengao Jiang, Qiang Tang   +5 more
doaj   +1 more source