Results 61 to 70 of about 8,304 (240)

Recent Updates on Anti-Inflammatory and Antimicrobial Effects of Furan Natural Derivatives

Journal of Inflammation Research, 2020
Mohammad Alizadeh,1,* Moludi Jalal,2 Khodaei Hamed,3 Amir Saber,2,* Sorayya Kheirouri,1 Fatemeh Pourteymour Fard Tabrizi,3 Negin Kamari2 1Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; 2Department of Nutritional Sciences,
Alizadeh M, Jalal M, Hamed K, Saber A, Kheirouri S, Pourteymour Fard Tabrizi F, Kamari N   +6 more
doaj  

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors [PDF]

, 2018
Crystallography has guided the hybridization of two series of Trypanosoma brucei N-myristoyltransferase (NMT) inhibitors, leading to a novel highly selective series.
Brand, Stephen, Brenk, Ruth, Collie, Iain, Davies, Kenneth, Frearson, Julie A., Gilbert, Ian H., Hallyburton, Irene, Harrison, Justin R., Mok, Ngai, Norval, Suzanne, Read, Kevin D., Robinson, David A., Simeons, Frederick R. C., Smith, Alasdair, Smith, Victoria, Stojanovski, Laste, Thompson, Stephen, Torrie, Leah S., Wyatt, Paul G.   +18 more
core   +3 more sources

Synthesis, Electronic Properties, and X-ray Structural Characterization of Tetrarylbenzo[1,2-\u3cem\u3eb\u3c/em\u3e:4,5-\u3cem\u3eb\u3c/em\u3e′]difuran Cation Radicals [PDF]

, 2008
Electroactive tetraarylbenzo[1,2-b:4,5-b′]difuran (BDF) and model diarylbenzofuran derivatives are synthesized and their structures are established by X-ray crystallography.
Lindeman, Sergey V., Rathore, Rajendra, Shukla, Ruchi, Wadumethrige, Shriya   +3 more
core   +1 more source

Synthesis of fluorinated oxygen- and sulfur-containing heteroaromatics [PDF]

, 2017
Milk protein concentrate (79% protein) reconstituted at 13.5% (w/v) protein was heated (90 °C, 25 min, pH 7.2) with or without added calcium chloride.
Jones, David J., Leary, Eileen M., O'Donovan, Fiona P., O'Sullivan, Timothy P.   +3 more
core   +1 more source

Translation inhibition by rocaglates activates a species-specific cell death program in the emerging fungal pathogen Candida auris [PDF]

, 2020
Fungal infections are a major contributor to infectious disease-related deaths worldwide. Recently, global emergence of the fungal pathogen Candida auris has caused considerable concern because most C.
Brown, Lauren E., Cowen, Leah E., Henkel, Thomas, Iyer, Kali R., Porco, Jr., John A., Robbins, Nicole, Whitesell, Luke   +6 more
core   +1 more source

N‐heterocyclic carbene‐based tetradentate Pt(II) phosphors for blue organic light‐emitting diodes: Molecular design, photophysics, and device performance

Bulletin of the Korean Chemical Society, EarlyView.
Structure‐oriented design of NHC‐based tetradentate Pt(II) complexes offers narrowband deep‐blue emission for OLEDs. This review highlights how steric shielding and electronic modulation regulate intermolecular interactions, excited‐state dynamics, and device performance, outlining design principles and outlines toward efficient and durable blue ...
Mingi Kim, Chan Hee Ryu, Kang Mun Lee
wiley   +1 more source

The Co-Administration of Paclitaxel with Novel Pyridine and Benzofuran Derivatives that Inhibit Tubulin Polymerisation: A Promising Anticancer Strategy

Pharmaceutics
Background: Paclitaxel (PTX), a crucial microtubule-stabilising agent in cancer treatment, is limited by its adverse effects and hydrophobic nature, which necessitate the use of toxic solvents.
Magdalena Perużyńska, Radosław Birger, Patrycja Kłos, Halina Kwiecień, Łukasz Struk, Jacek G. Sośnicki, Laurence Lafanechère, Marek Droździk   +7 more
doaj   +1 more source

Polysilane‐Supported Nickel as an Efficient Catalyst for the Hydrogenation of Aromatic Compounds†

Chinese Journal of Chemistry, EarlyView.
A Ni/Si catalyst obtained from the reaction of poly(monohydro)silane with Ni(cod)2 serves as an effective heterogeneous catalyst for the hydrogenation of arenes under reaction conditions that are significantly milder than those required for conventional nickel‐based catalysts such as Raney nickel.
Hiromu Baba, Yusuke Sunada
wiley   +1 more source

Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MSn techniques [PDF]

The number of so-called new psychoactive substances (NPS) is still increasing by modification of the chemical structure of known (scheduled) drugs. As analogues of amphetamines, 2-aminopropyl-benzofurans were sold.
A Stanczuk, AG Helfer, AH Ewald, C Renzulli, DK Dalvie, DK Wissenbach, DK Wissenbach, FT Peters, FW McLafferty, Hans H. Maurer, HH Maurer, J Dinger, J Welter, J Welter, JC Connelly, Jessica Welter, JF Casale, JM Fur Le, L Iversen, Markus R. Meyer, MR Meyer, MR Meyer, Pierce Kavanagh, RM Smith, Simon D. Brandt, T Kobayashi, T Ou, V Ravindranath, V Sharma, WL Chan   +29 more
core   +1 more source

Emerging Trends in Organic Photoreactions Utilizing Disulfides

European Journal of Organic Chemistry, EarlyView.
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar, Bolormaa Bayarkhuu, Hong Y. Cho, Jeehye Byun   +3 more
wiley   +1 more source