Results 61 to 70 of about 8,390 (243)

Synthesis, Electronic Properties, and X-ray Structural Characterization of Tetrarylbenzo[1,2-\u3cem\u3eb\u3c/em\u3e:4,5-\u3cem\u3eb\u3c/em\u3e′]difuran Cation Radicals [PDF]

, 2008
Electroactive tetraarylbenzo[1,2-b:4,5-b′]difuran (BDF) and model diarylbenzofuran derivatives are synthesized and their structures are established by X-ray crystallography.
Lindeman, Sergey V., Rathore, Rajendra, Shukla, Ruchi, Wadumethrige, Shriya   +3 more
core   +1 more source

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors [PDF]

, 2018
Crystallography has guided the hybridization of two series of Trypanosoma brucei N-myristoyltransferase (NMT) inhibitors, leading to a novel highly selective series.
Brand, Stephen, Brenk, Ruth, Collie, Iain, Davies, Kenneth, Frearson, Julie A., Gilbert, Ian H., Hallyburton, Irene, Harrison, Justin R., Mok, Ngai, Norval, Suzanne, Read, Kevin D., Robinson, David A., Simeons, Frederick R. C., Smith, Alasdair, Smith, Victoria, Stojanovski, Laste, Thompson, Stephen, Torrie, Leah S., Wyatt, Paul G.   +18 more
core   +3 more sources

The Co-Administration of Paclitaxel with Novel Pyridine and Benzofuran Derivatives that Inhibit Tubulin Polymerisation: A Promising Anticancer Strategy

Pharmaceutics
Background: Paclitaxel (PTX), a crucial microtubule-stabilising agent in cancer treatment, is limited by its adverse effects and hydrophobic nature, which necessitate the use of toxic solvents.
Magdalena Perużyńska, Radosław Birger, Patrycja Kłos, Halina Kwiecień, Łukasz Struk, Jacek G. Sośnicki, Laurence Lafanechère, Marek Droździk   +7 more
doaj   +1 more source

Polysilane‐Supported Nickel as an Efficient Catalyst for the Hydrogenation of Aromatic Compounds†

Chinese Journal of Chemistry, EarlyView.
A Ni/Si catalyst obtained from the reaction of poly(monohydro)silane with Ni(cod)2 serves as an effective heterogeneous catalyst for the hydrogenation of arenes under reaction conditions that are significantly milder than those required for conventional nickel‐based catalysts such as Raney nickel.
Hiromu Baba, Yusuke Sunada
wiley   +1 more source

Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MSn techniques [PDF]

The number of so-called new psychoactive substances (NPS) is still increasing by modification of the chemical structure of known (scheduled) drugs. As analogues of amphetamines, 2-aminopropyl-benzofurans were sold.
A Stanczuk, AG Helfer, AH Ewald, C Renzulli, DK Dalvie, DK Wissenbach, DK Wissenbach, FT Peters, FW McLafferty, Hans H. Maurer, HH Maurer, J Dinger, J Welter, J Welter, JC Connelly, Jessica Welter, JF Casale, JM Fur Le, L Iversen, Markus R. Meyer, MR Meyer, MR Meyer, Pierce Kavanagh, RM Smith, Simon D. Brandt, T Kobayashi, T Ou, V Ravindranath, V Sharma, WL Chan   +29 more
core   +1 more source

Benzothiazole durch C-C-Spaltung von alpha-[(2-Nitrophenyl)thio]ketonen [PDF]

, 1984
Einwirkung von Ammoniak bzw. Natronlauge auf die -[(2-Nitrophenyl)thio]ketone 4, 11a-c und 16 führt unter CC-Spaltung zu den Benzothiazol-N-oxid-Derivaten 8, 12ac und 17; aus dem 3-[(2-Nitrophenyl)thio]-4-piperidon-Derivat 22 entsteht der 2 ...
Babichev, Birkofer, Eiden, Gordon, Hoffmann, Hofmann, House, Kuehne, Linke, Schröder, Takahashi   +10 more
core   +1 more source

Translation inhibition by rocaglates activates a species-specific cell death program in the emerging fungal pathogen Candida auris [PDF]

, 2020
Fungal infections are a major contributor to infectious disease-related deaths worldwide. Recently, global emergence of the fungal pathogen Candida auris has caused considerable concern because most C.
Brown, Lauren E., Cowen, Leah E., Henkel, Thomas, Iyer, Kali R., Porco, Jr., John A., Robbins, Nicole, Whitesell, Luke   +6 more
core   +1 more source

Diastereoselective Copper‐Catalyzed Defluorosilylation of Pentafluoroethyl Alkenes to Access Polyfluorinated Allylsilanes

Chinese Journal of Chemistry, EarlyView.
Under copper(I) catalysis, pentafluoroethylated alkenes can undergo smooth defluorosilylation to generate novel polyfluorinated products. The reaction exhibits high levels of diastereoselectivities for obtaining multisubstituted allylsilanes with control of the double bond geometry.
Yuwei Zong, Yihan Tang, Gavin Chit Tsui
wiley   +1 more source

Remarkable Formation of Indene Derivatives Upon Friedel–Crafts Acylation Reactions

European Journal of Organic Chemistry, EarlyView.
This shows indene derivatives. Under the reaction conditions of a Friedel–Crafts acylation, alkyl benzenes underwent an unprecedented cyclopentannulation furnishing indene derivatives. Alkylbenzene derivatives react with two equivalents of pivaloyl chloride (PivCl) in the presence of aluminum trichloride under formation of indene derivatives with up to
Leah Bantel, Neels Kruse, Marc Schmidtmann, Jens Christoffers   +3 more
wiley   +1 more source

Toxicity of Compounds Isolated from White Snakeroot () to Adult and Larval Yellow Fever Mosquitoes ()

Natural Product Communications, 2016
Botanicals have been the source for several classes of pesticides for mosquitoes. However, increasing resistance to these products and reduced numbers of choices necessitate the search for new active ingredients. Ageratina altissima (L.) King & H.
Alden S. Estep, James J. Becnel, Stephen T. Lee   +2 more
doaj   +1 more source