Results 61 to 70 of about 6,146 (188)

Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea

Journal of Enzyme Inhibition and Medicinal Chemistry
The phytochemical investigation of the methanol extract of the seeds of Magydaris pastinacea afforded two undescribed benzofuran glycosides, furomagydarins A-B (1, 2), together with three known coumarins.
Shiu-Wen Huang, Ming Jen Hsu, Hsiu-Chen Chen, Rita Meleddu, Simona Distinto, Elias Maccioni, Filippo Cottiglia   +6 more
doaj   +1 more source

Benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: A review

Journal of Research in Medical Sciences, 2015
Benzofuran as an important heterocyclic compound is extensively found in natural products as well as synthetic materials. Since benzofuran drivatives display a diverse array of pharmacological activities, an interest in developing new biologically active
Ghadamali Khodarahmi, Parvin Asadi, Farshid Hassanzadeh, Elham Khodarahmi   +3 more
doaj   +1 more source

Facile access to benzofuran derivatives through radical reactions with heteroatom-centered super-electron-donors

Nature Communications, 2023
The development of suitable electron donors is critical to single-electron-transfer (SET) processes. The use of heteroatom-centered anions as super-electron-donors (SEDs) for direct SET reactions has rarely been studied.
Shichun Jiang, Wei Wang, Chengli Mou, Juan Zou, Zhichao Jin, Gefei Hao, Yonggui Robin Chi   +6 more
doaj   +1 more source

Some recent approaches to the synthesis of 2-substituted benzofurans

, 2009
In their structural multiplicity and in the extent to which they occur in nature the derivatives of benzofuran are significantly lesser than the isoelectronic analogue indoles.
Nieddu, Giammario, PORCHEDDU, A., De Luca, Lidia Vera Giovanna, Porcheddu, Andrea, NIEDDU, G., Giacomelli, Giampaolo   +5 more
core   +1 more source

Photosensitizing Au(I) Catalysis With Coumarins

Chemistry – A European Journal, EarlyView.
A Au(I) complex with a tethered coumarin fragment was synthesized and characterized by UV‐vis and emission spectroscopy. Its ability to facilitate photo‐driven cross‐coupling reactions through single‐electron and energy transfer events was evaluated. ABSTRACT Gold catalysis shows versatility in a wide range of challenging transformations, wherein light‐
Liliana Capulín Flores, Jacob J. van der Wal, Johannes E. M. N. Klein   +2 more
wiley   +1 more source

Practical synthesis of indoles and benzofurans in water using a heterogeneous bimetallic catalyst

Beilstein Journal of Organic Chemistry, 2013
This paper describes the preparation of indoles, azaindoles and benzofurans in pure water by using a new heterogeneous Pd–Cu/C catalyst through a cascade Sonogashira alkynylation–cyclization sequence. Details of the optimization studies and the substrate
Cybille Rossy, Eric Fouquet, François-Xavier Felpin   +2 more
doaj   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

Chemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal, Alexandre Millanvois, Louis Fensterbank, Cyril Ollivier   +3 more
wiley   +1 more source

From Data to Dimers: Engineering Acene Derivatives for Photovoltaic Singlet Fission

Chemistry – A European Journal, EarlyView.
Excited‐state energies of acene derivatives are predicted using a ChemBERTa‐based regression model and subsequently used to screen candidates for photovoltaic singlet fission using dimer–monomer benchmarked energetic criteria. Promising candidates are predominantly 5‐ and 6‐fused heteroacenes, which offer enhanced stability and higher triplet energies ...
Alexander J. Cross, Rik R. Tykwinski, J. Terence Blaskovits   +2 more
wiley   +1 more source

Palladium-Catalyzed Oxidative Cyclization of 3-Phenoxyacrylates: An Approach To Construct Substituted Benzofurans from Phenols

, 2016
In this paper, a novel and applicable synthesis of benzofurans from commercially available phenols and propiolate through the direct oxidative cyclization has been developed.
Pinhua Li (1457875), Lei Wang (6656), Yicheng Zhang (790286), Chengliang Li (1479382)   +3 more
core   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

European Journal of Organic Chemistry, EarlyView.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu, Mauro Uras, Angelo Frongia   +2 more
wiley   +1 more source