Results 81 to 90 of about 4,414 (202)

Electrochemical Three‐Component Synthesis of Heteroaryl Sulfonates

European Journal of Organic Chemistry, Volume 29, Issue 27, 17 July 2026.
An electrochemical, metal‐free three‐component strategy for direct C(sp2)─H sulfonation of electron‐rich heteroarenes using SO2 and alcohols is described. Utilizing inexpensive graphite electrodes and practical SO2 stock solutions under mild conditions, this method provides straightforward access to heteroaryl sulfonates from simple building blocks ...
Po‐Chung Chien, Harald Kelm, Georg Manolikakes   +2 more
wiley   +1 more source

Polysilane‐Supported Nickel as an Efficient Catalyst for the Hydrogenation of Aromatic Compounds†

Chinese Journal of Chemistry, Volume 44, Issue 14, Page 2277-2282, 15 July 2026.
A Ni/Si catalyst obtained from the reaction of poly(monohydro)silane with Ni(cod)2 serves as an effective heterogeneous catalyst for the hydrogenation of arenes under reaction conditions that are significantly milder than those required for conventional nickel‐based catalysts such as Raney nickel.
Hiromu Baba, Yusuke Sunada
wiley   +1 more source

Pharmacology, Medicinal Chemistry, and Therapeutic Potential of Imidazoline Receptor Ligands

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Building on the excellent review article by Dardonville and Rozas (2004), this paper summarizes the most representative ligands of imidazoline receptors (IR; I1, I2, and I3) and updates their pharmacological profiles. Although not exhaustive, it provides a solid starting point for understanding the significance of I2 IRs as promising therapeutic ...
Maria‐Eleni Kouridaki, Mercè Pallàs, Carmen Escolano   +2 more
wiley   +1 more source

Palladium‐Catalyzed Cascade Sonogashira Cyclization for Synthesis of Fluorescent Benzofuran Amino Acids

ChemistryOpen
In this work, we developed an efficient methodology for the synthesis of benzofurans using Sonogashira‐type reactions between iodotyrosine and alkyne derivatives (aromatic, heteroaromatic, and alkyl), catalyzed by palladium salts. The methodology enabled
Giuseppe E. Figlino, Nicaely M. O. Pereira, Erick L. Bastos, Mônica F. Z. J. Toledo, Milene M. Hornink, Flávia Manarin, Hélio A. Stefani   +6 more
doaj   +1 more source

Design and Synthesis of Novel Imidazo[4,5‐c]pyridine Derivatives, Evaluation of Their Activity Against Hepatitis C Virus and In Silico Prediction of Their Binding Mode to NS4B Protein

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
A series of 18 novel imidazo[4,5‐c]pyridines was synthesized, and their anti‐HCV activity was evaluated. Compound 30b was identified as the most promising one, with EC50 = 6.61 µM. Molecular docking studies indicated the NS4B protein of the HCV as a potential target of these derivatives.
Eftychia Karampella, George Mpekoulis, Maria Georgiou, Iris Kolida, Katerina I. Kalliampakou, Eirini P. Kollia, Eleni V. Mikropoulou, Maria Halabalaki, Christos T. Chasapis, Niki Vassilaki, Nikolaos Lougiakis   +10 more
wiley   +1 more source

Effect of butylphthalide on the serum uric acid and clinical outcomes of patients with ischemic stroke

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Objective To investigate the effect of butylphthalide on the serum uric acid level and clinical outcomes of patients with ischemic stroke.  Methods A total of 160 patients with ischemic stroke were randomly divided into 2 groups: treatment group and
Dan-dan LU, Shu-yan WEI, Li WAN, Jing WANG, Lan HOU, Xue-zheng LU, Wei ZHANG, Pei WANG   +7 more
doaj  

Monitoring of new psychoactive substances in France: update of addictovigilance data. [PDF]

Eur J Public Health
Autellet A, Lacroix C, Batisse A, Micallef J, Fouilhe N, Le Boisselier R, Peyrière H, Eiden C, French Addictovigilance Network.   +8 more
europepmc   +1 more source

Chiral cyclopropenimine-catalyzed enantioselective Michael reactions of phenol and benzofuran-derived α,β-unsaturated pyrazolamides with benzophenone-imine of glycine esters. [PDF]

Beilstein J Org Chem
Bai Y, Wang XY, Zhu SK, Shen YT, Zhang SY, Wang PA.   +5 more
europepmc   +1 more source

Iridium-Catalyzed Diorganosilylene Insertion into C(sp²)-O Bond of Oxacycles Using Aryldiorganosilanes as Silylene Transfer Reagents. [PDF]

ACS Cent Sci
Song Y, Suginome M.
europepmc   +1 more source

The 'one-pot' preparation of substituted benzofurans

ARKIVOC, 2004
Márton Csékei, Zoltán Novák, Géza Timári, András Kotschy   +3 more
doaj   +1 more source