Practical synthesis of indoles and benzofurans in water using a heterogeneous bimetallic catalyst
This paper describes the preparation of indoles, azaindoles and benzofurans in pure water by using a new heterogeneous Pd–Cu/C catalyst through a cascade Sonogashira alkynylation–cyclization sequence. Details of the optimization studies and the substrate
Cybille Rossy +2 more
doaj +1 more source
Climate change‐driven expansion of goosegrass highlights risks to global food production
Climate change is expanding the climatic suitability of Eleusine indica into temperate agricultural regions, increasing its overlap with major soybean and maize production areas. These findings highlight a growing global threat to food security and the need for proactive weed management strategies.
Thiago Deomar Ludwig +4 more
wiley +1 more source
Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes
A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship.
Toan Dao-Huy +7 more
doaj +1 more source
1,3-Dien-5-ynes: Versatile Building Blocks for the Synthesis of Carbo- and Heterocycles [PDF]
1,3-Dien-5-ynes have been extensively used as starting materials for the synthesis of a wide number of different carbo- and heterocycles. The aim of this review is to give an overview of their utility in organic synthesis, highlighting the variety of ...
Aguilar, Enrique +3 more
core +1 more source
New benzofuran derivatives as an antioxidant agent
A series of substituted benzofuran derivatives were synthesized and characterized by spectral data. Some of the synthesized compounds were tested for in vitro antioxidant activity. Some of them have shown very good antioxidant activity. These compounds were also tested for antimicrobial activity against microbial strains viz.
Rindhe, S. S. +2 more
openaire +3 more sources
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Efforts Towards Alkyne Insertion Reactions Via Oxidative Dearomatization [PDF]
Development of 1,2-dihydro naphthalene precursors are considered to be one of the most important reactions as they form versatile framework for natural product synthesis. Efforts are on the way to develop dihydronapthalene, benzofuran and indene using an
Kumar, Rahul
core
Advances in organic UV filters for sunscreens over the past decade
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon +4 more
wiley +1 more source
Ductile Metal Oxides Impregnated on Magnetite: New Catalysts in Organic Synthesis [PDF]
Ramón's group has designed a simple, robust and inexpensive methodology for the impregnation of different transition metal oxides on the surface of magnetite and their use in ...
Ramón, Diego J.
core +2 more sources
Research & Development Department, Indian Drugs & Pharmaceuticals Limited, Hyderabad-500 037 Manuscript received 4 March 1978, revised 4 July 1978, accepted 27 July 1978 A number of aryl benzofuran-, 3-methylbenzofuran- and 5-metboxybenzofuran-2- carbamates and carbamides have been synthesized and screened for \(in vitro\) antibacterial ...
D. R. SHRIDHAR +4 more
openaire +1 more source

