Results 191 to 200 of about 124,782 (320)

The Ascent of Supramolecular Polymers and Gels in Asymmetric Catalysis

open access: yesChemistry – A European Journal, EarlyView.
SPs and gels emerged as modular platforms for asymmetric catalysis. This review ranks literature reports according to the achiral or chiral nature of the monomers bearing the catalytic site. New paradigms showcased by this approach are particularly highlighted, such as catalysts operating with a low amount of chiral inducers, or with no chiral inducer,
Ran Chen   +2 more
wiley   +1 more source

A Diverse Array of Catalytic Photoredox Reactions Based on Aluminum(III)‐Salen Complexes: Understanding the Enhancement of Catalytic Activity via Amine Association

open access: yesChemistry – A European Journal, EarlyView.
We report the diversity of the photoredox reactions based on Al‐salen catalysts. The combination of an Al‐salen catalyst with an amine under visible‐light irradiation allowed the reductive transformations of aryl chlorides, carbonyl compounds, and perfluoroalkylarenes, and the oxidative transformations of amines.
Yoshihiro Nishimoto   +6 more
wiley   +1 more source

Proton first: rationalizing a proton transfer in a protein‐fragment complex

open access: yesChemMedChem, Accepted Article.
We present a combination of experimental and theoretical approaches to decipher the molecular recognition event of benzoic acid complexed with Protein Kinase A. The publicly known crystal structure suggests the protonated form of benzoic acid to be complexed with Protein Kinase A.
Helge Vatheuer   +6 more
wiley   +1 more source

Inhibition of the Clathrin Terminal Domain—Amphiphysin Protein–Protein Interaction. Probing the Pitstop 2 Aromatic Moiety

open access: yesChemMedChem, EarlyView.
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard   +10 more
wiley   +1 more source

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