Results 71 to 80 of about 3,127 (182)

Exploring Subtilisin Inhibition to Discover Antimalarial Drugs: Insights into Medicinal Chemistry and Drug Discovery

Pharmaceuticals
Introduction: Malaria is a tropical disease caused by the parasite Plasmodium sp., which is considered a significant public health challenge, particularly in Africa. Among the species related to human infection, P. falciparum and P.
Margarida Cochicho Leonardo, Sonaly Lima Albino, Wallyson Junio Santos de Araújo, Maria Verônica de Barros Nascimento, Juan David Rodríguez-Macías, Edgar Alexander Marquez Brazon, Ricardo Olimpio de Moura, Fátima Nogueira, Igor José dos Santos Nascimento   +8 more
doaj   +1 more source

Defense Molecules of the Invasive Plant Species Ageratum conyzoides

Molecules
Ageratum conyzoides L. is native to Tropical America, and it has naturalized in many other tropical, subtropical, and temperate countries in South America, Central and Southern Africa, South and East Asia, Eastern Austria, and Europe.
Hisashi Kato-Noguchi, Midori Kato
doaj   +1 more source

Synthesis of Deuterated Benzopyran Derivatives as Selective COX-2 Inhibitors with Improved Pharmacokinetic Properties. [PDF]

ACS Med Chem Lett, 2014
Zhang Y, Tortorella MD, Wang Y, Liu J, Tu Z, Liu X, Bai Y, Wen D, Lu X, Lu Y, Talley JJ.   +10 more
europepmc   +1 more source

From biomass to bioactivity: <i>Butea monosperma</i> bark-derived carbon quantum dots for benzopyran synthesis and their <i>in silico</i> studies. [PDF]

RSC Adv
Teli S, Soni S, Rana N, Manhas A, Agarwal S.   +4 more
europepmc   +1 more source

Synthesis of Benzopyrans and Quinolines with Nitrogenated Chain and Their Cytotoxicity Against Human Cancer Cell Lines. [PDF]

ChemMedChem
Álvaro BS, Mackenzie TA, Ramos MC, García A, Villarroel-Vicente C, Vila L, Tormo JR, Cortes D, Cabedo N.   +8 more
europepmc   +1 more source

Development of coumarin-sulfonate scaffolds for cholinesterase inhibition: experimental and computational studies toward Alzheimer's disease therapy. [PDF]

RSC Adv
Mughal EU, Naeem N, Cheema AS, Othman GA, Sadiq A, Bayrak S, Kılınç N, Hawsawi MB, Gomha SM, Almaz Z.   +9 more
europepmc   +1 more source

Rational Design and Evaluation of Novel TGR5 Agonists for Diabetes. [PDF]

Molecules
Bhimanwar RS, Detwiler Z, Zhu JG, Saghafi ST, Winder CA, Davis DB, Mittal A, Sharma V, Harris DA, Chaudhari SN.   +9 more
europepmc   +1 more source

Novel bioactive compounds from marine-derived endosymbiotic Penicillium fungi reported during 2020-2025. [PDF]

Nat Prod Bioprospect
Omran SA, Elnaggar MS, Youssef FS, El-Moghazy SA.   +3 more
europepmc   +1 more source

Kabbe condensation: a comprehensive review of spirochromanone synthesis and medicinal applications. [PDF]

RSC Adv
Samandram R, Komarasamy B, Murugan P, Jayaraj P, Vemparala M, Fareed Chaman A, Anaikutti P.   +6 more
europepmc   +1 more source

In vitro anticancer studies of new derivatives based on the furanocoumarin scaffold. [PDF]

Sci Rep
Olejarz W, Augustynowicz-Kopeć E, Głogowska A, Napiórkowska M, Szostek T, Filipek A, Szulczyk D.   +6 more
europepmc   +1 more source