Results 41 to 50 of about 3,529 (194)
A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions [PDF]
, 2018 Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings ...
Donaldson, William A. +12 more
core +4 more sources
A Structure–Activity Relationship Study on the Antioxidant Properties of Dithiocarbamic Flavanones
AntioxidantsThe antioxidant properties of 3-dithiocarbamic flavanones have been investigated. The influence of the halogen substituents on ring A of the flavanones and the nature of the secondary amine from the dithiocarbamic moiety have been accounted.
Mihail Lucian Birsa +1 more
doaj +1 more source
Marine Drugs, 2013 The benzopyran compound obtained by cultivating a mangrove-derived strain, Streptomyces xiamenensis strain 318, shows multiple biological effects, including anti-fibrotic and anti-hypertrophic scar properties.
Lei Feng +8 more
doaj +1 more source
Finding Characteristic Substructures for Metabolite Classes [PDF]
, 2012 We introduce a method for finding a characteristic substructure for a set of molecular structures. Different from common approaches, such as computing the maximum common subgraph, the resulting substructure does not have to be contained in its exact form
Böcker, S. +3 more
core +2 more sources
Phenolics: from chemistry to biology [PDF]
, 2009 In recent years, few classes of natural products have received as much attention as phenolics and polyphenols. This special issue of Molecules, “Phenolics and Polyphenolics”, is a remarkable confirmation of this trend.
Andrade, P.B. +3 more
core +1 more source
Unusual Swelling Behavior of Hydrogels Modified with Spiropyran as Appendage or Crosslinker
Advanced Functional Materials, EarlyView.Not so innocent after all—spiropyran crosslinkers in methylenebisacrylamide‐crosslinked poly(acrylamide‐co‐acrylic acid) hydrogels increase crosslinking density, but also, counterintuitively, increase swelling. Charge complexation, cooperative chemo‐mechanical effects, and aggregation may explain these observations.
Michael M. Lerch +7 more
wiley +1 more source
Enteric helminths promote Salmonella co-infection by altering the intestinal metabolome [PDF]
, 2017 Intestinal helminth infections occur pre dominantly in regions where exposure to enteric bacterial pathogens is also common. Helminth infections inhibit host immunity against microbial pathogens, which has largely been attributed to the induction of ...
Borchers, Christoph H. +13 more
core +1 more source
Advanced Science, EarlyView.Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan +12 more
wiley +1 more source
International Journal of Photoenergy, 2003 The photochromic properties of three ferrocenyl-[2H]-benzopyrans were investigated under monochromatic irradiation and compared with those of their phenyl homologues.
Pierre Brun +4 more
doaj +1 more source
Chemical Constituents of Leaves and Barks of Melicope Hookeri T.G. Hartley [PDF]
, 2006 Phytochemical investigation on the leaves and bark of Melicope hookeri T.G. Hartley (Rutaceae) has resulted in the isolation and identification of three flavonoids, ayanin, ombuin and kumatakenin, two coumarins, umbelliferone and scopoletin and p ...
Ali, Abdul Manaf +6 more
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