Results 41 to 50 of about 17,647 (331)

Hydroxylated derivatives of dimethoxy-1,4-benzoquinone as redox switchable earth-alkaline metal ligands and radical scavengers [PDF]

, 2013
Benzoquinones (BQ) have important functions in many biological processes. In alkaline environments, BQs can be hydroxylated at quinoid ring proton positions.
Bogeski, Ivan, Gulaboski, Rubin, Haeri, Haleh H., Hoth, Markus, Kappl, Reinhard, Mirceski, Valentin, Mitrev, Sasa, Pasieka, Bastian, Petreska Stanoeva, Jasmina, Saul, Stephanie, Stefova, Marina   +10 more
core   +1 more source

The MarR-Type Repressor MhqR Confers Quinone and Antimicrobial Resistance in Staphylococcus aureus [PDF]

, 2019
Aims: Quinone compounds are electron carriers and have antimicrobial and toxic properties due to their mode of actions as electrophiles and oxidants.
Fritsch, Verena Nadin, Loi, Vu Van, Busche, Tobias, Sommer, Anna, Tedin, Karsten, Nürnberg, Dennis J., Kalinowski, Jörn, Bernhardt, Jörg, Fulde, Marcus, Antelmann, Haike   +9 more
core   +1 more source

Synthesis, Spectral analysis and Anti-microbial properties of Cu, Ag, Au complexes of 2, 5-dihydroxy-1, 4-benzoquinone and 3, 6-dichloro-2, 6-dihydroxy-1, 4-benzoquinone

Results in Chemistry, 2021
Many complexes of Cu, Ag, Au in combination with dianions derived from 2, 5-dihydroxy-1, 4-benzoquinone and 3, 6-dichloro-2, 6-dihydroxy-1, 4-benzoquinones have been synthesized and analysed for their antimicrobial activity.
M. Amin Mir, Anuj Kumar, Shailendra P. Madwal, M.M.S. Jassal   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells [PDF]

, 2014
Glutaminase, which converts glutamine to glutamate, is involved in Warburg effect in cancer cells. Two human glutaminase genes have been identified, GLS (GLS1) and GLS2.
Chang, Hsin-Yu, Chang, Hsun-Shuo, Chao, Yu-Sheng, Chen, Ih-Shen, Hsu, Hsing-Yu, Kumar, Chidambaram Ramesh, Lee, Chih-Hao, Lee, Jinq-chyi, Lee, Shiow-Ju, Lee, Yue-Zhi, Qiu, Ya-Qi, Yang, Cheng-Wei   +11 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Electrochemistry of potentially bioreductive alkylating quinones : Part 1. Electrochemical properties of relatively simple quinones, as model compounds of mitomycin- and aziridinylquinone-type antitumour agents [PDF]

, 1990
The influence of methyl-, hydroxy and amino substituents on the electrochemical behaviour of simple 1,4-naphtho-and 1,4-benzoquinones, model compounds of many quinoid antitumour agents, in aqueous media was studied. Significant changes in electrochemical
Bos, M., Driebergen, R.J., Hartigh, J. den, Holthuis, J.J.M., Hulshoff, A., Linden, W.E. van der, Oort, W.J. van, Postma Kelder, S.J., Reinhoudt, D.N., Verboom, W.   +9 more
core   +2 more sources

Engineering Porous Hollow Metal‐Poly(Heptazine Imide) Spheres: An Optimized Synthetic Strategy for Controlling Surface, Morphology, and Properties

Advanced Functional Materials, EarlyView.
Hollow poly(heptazine imide) spheres are prepared through a novel approach that integrates hard templating with ionothermal synthesis. This method enables precise control over surface area, pore volume, hydrophilicity, light absorption, band position, and metal composition. These tunable properties facilitate the customized design of semiconductors for
Lingli Ni, Erik Troschke, Henrik Vorwerk, Shiva Shahbazi Avarvand, Andreas Stihl, Nadzeya Brezhneva, Marius Hermesdorf, Desirée Leistenschneider, Felix H. Schacher, Jacob Schneidewind, Martin Oschatz   +10 more
wiley   +1 more source

CHEMICAL ANALYSIS OF NEW RECORDED SPECIES Acalypha australis L. AT IRAQ

The Iraqi Journal of Agricultural science, 2023
This study was aimed to chemical analysis of new recorded species Acalypha australis L. Plant samples collected from cultivated gardens and fields as well as road sides.
I. A.M. Al-Dobaissi
doaj   +1 more source

Near‐Infrared Emitting Lanthanide Catecholate Giant Single Crystals – Morphology Control and Photon Down‐Conversion

Advanced Functional Materials, EarlyView.
Controlled syntheses of lanthanide coordination polymers based on the dihydroxybenzoquinone (DHBQ) organic linker afforded large single crystals of Ln‐DHBQ CPs (Ln = Yb, Nd). A novel structural variant of Yb‐DHBQ is identified by means of single crystal diffraction analysis.
Marina I. Schönherr, Alexander Biewald, Andre Mähringer, Thaddäus J. Koller, Peter Mayer, Markus Döblinger, Achim Hartschuh, Dana D. Medina   +7 more
wiley   +1 more source