Results 111 to 120 of about 547 (150)

Copper-promoted aerial oxidation of benzothiadiazines: access to benzothiadiazine S-oxide heterocycles

Dalton Transactions, 2015
Aerial oxidation of benzothiadiazines selectively affords the corresponding benzothiadiazine S-oxides in the presence of Cu2+ ions. Structural studies reveal that the S-oxide appears to be a strong hydrogen-bond acceptor.
Ewan R, Clark, John J, Hayward, Bryce J, Leontowicz, Muhammad U, Anwar, Melanie, Pilkington, Jeremy M, Rawson   +5 more
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Determination of kinetic parameters of enantiomerization of benzothiadiazines by DCXplorer

Chirality, 2010
AbstractBenzothiadiazines differently substituted at the sulfonamidic nitrogen atom, at the stereogenic carbon atom and at the anilinic nitrogen atom have been synthesized and fully characterized. Enantioseparation of these compounds has revealed rapid on‐column enantiomerization.
CANNAZZA, Giuseppe, CARROZZO, Marina Maria, BATTISTI, UMBERTO MARIA, BRAGHIROLI, Daniela, PARENTI, Carlo, Troisi, Alessandro, Troisi, Luigino   +6 more
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The Diabetogenic Activity of Benzothiadiazines

JAMA, 1964
To the Editor:— Because benzothiadiazines have been used so widely for many diverse conditions—including even obesity—any comment on the diabetogenic effect of this class of compounds is important. It is not surprising that a respected senior investigator such as Dr.
Frederick W. Wolff, William W. Parmley
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Benzothiadiazines and Diabetes Mellitus

JAMA, 1964
To the Editor:— Wolff and his associates ( JAMA 185 :568 [Aug 17] 1963) recently indicated that the induction of diabetes mellitus represents a not infrequent complication associated with the long-term administration of benzothiadiazine diuretics. The evidence consisted of the observation that the fasting blood sugar value in 45 patients averaged 97 ...
Edward D. Freis
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Spectrophotometric determination of benzothiadiazines in dosage forms

Talanta, 1986
The analytical utility of ethyl acetoacetate for the spectrophotometric determination of benzothiadiazine diuretics has been studied. The procedure developed is based on coupling of the diazotized drugs with the reagent, which possesses an active methylene group. The stoichiometry of the reaction is presented.
F, Belal, M, Rizk, F, Ibrahiem, M S, El-Din   +3 more
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The Preparation of 4-Substituted Benzothiadiazines

Journal of Medicinal Chemistry, 1964
E, MAGNIEN, W, TOM, W, OROSHNIK
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Blockade Of The Diuretic Action Of Benzothiadiazines.

, 1966
PhD ; Chemistry ; University of Michigan, Horace H. Rackham School of Graduate Studies ; http://deepblue.lib.umich.edu/bitstream/2027.42/184609/2/6708335 ...
Ross, Charles Richard
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From 1,2,4-Benzothiadiazines

, 2002
H. Ulrich
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Ionization constants of benzothiadiazines

, 1979
Hennig, Ursula G.
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Hydrolysis of Benzothiadiazines

Journal of Pharmaceutical Sciences, 1971
The hydrolysis of hydrochlorothiazide and two other hydrothiazides was studied as a function of pH. Reversible kinetics were observed for the hydrolytic reaction, and a bell-shaped pH-rate profile was obtained. The equilibrium constant, however, was relatively independent of hydrogen-ion concentration.
J A, Mollica, C R, Rehm, J B, Smith, H K, Govan   +3 more
openaire   +2 more sources