Results 111 to 120 of about 763 (164)

The extrarenal effects of diuretics on potassium homeostasis in the acutely nephrectomized rat [PDF]

, 1982
Tanoue, Lynn T.
core   +1 more source

[Thin-layer chromatography of benzothiadiazine derivatives].

Acta poloniae pharmaceutica, 1966
Z, Margasiński, R, Danielak, H, Rafalowska   +2 more
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Hydrolysis of Benzothiadiazines

Journal of Pharmaceutical Sciences, 1971
The hydrolysis of hydrochlorothiazide and two other hydrothiazides was studied as a function of pH. Reversible kinetics were observed for the hydrolytic reaction, and a bell-shaped pH-rate profile was obtained. The equilibrium constant, however, was relatively independent of hydrogen-ion concentration.
J A, Mollica, C R, Rehm, J B, Smith, H K, Govan   +3 more
exaly   +3 more sources

Copper-promoted aerial oxidation of benzothiadiazines: access to benzothiadiazine S-oxide heterocycles

Dalton Transactions, 2015
Aerial oxidation of benzothiadiazines selectively affords the corresponding benzothiadiazine S-oxides in the presence of Cu2+ ions. Structural studies reveal that the S-oxide appears to be a strong hydrogen-bond acceptor.
Ewan R Clark, John J Hayward, Melanie Pilkington   +2 more
exaly   +3 more sources

The Diabetogenic Activity of Benzothiadiazines

JAMA - Journal of the American Medical Association, 1964
To the Editor:— Because benzothiadiazines have been used so widely for many diverse conditions—including even obesity—any comment on the diabetogenic effect of this class of compounds is important. It is not surprising that a respected senior investigator such as Dr.
Frederick W. Wolff, William W. Parmley
exaly   +2 more sources

Hypotensive 1,2,4-Benzothiadiazines

Journal of Medicinal Chemistry, 1963
B A, BIERBAUM, J J, TRAVERSO, C W, WHITEHEAD   +2 more
exaly   +3 more sources

DIABETOGENIC ACTION OF BENZOTHIADIAZINES

Lancet, The, 1963
N. Samaan, C.T. Dollery, Russell Fraser
exaly   +2 more sources

Syntheses of 1,2,4-benzothiadiazine 1-oxides and 1,2,4-benzothiadiazines

Journal of Organic Chemistry, 1980
Neville Finch, Salvatore Ricca, Lincoln H. Werner, Ronald Rodebaugh   +3 more
exaly   +2 more sources

Some 1H-4,1,2-benzothiadiazines and 1H-4,1,2-benzothiadiazine 4,4-dioxides

Journal of the Chemical Society, Perkin Transactions 1, 1978
Interamolecular displacement of the o-nitro-group of 1-(2-nitrophenylthio)pyruvaldehyde 1-phenylhydrazone, under basic conditions, gives 3-acetyl-1-phenyl-1H-4,1,2-benzothiadiazine which was oxidised to the 4,4-dioxide. Ethyl 2-nitrophenylsulphonylglyoxylate phenylhydrazone gives only 2-nitrodiphenylamine under these conditions, but reduction to the 2 ...
Donald E. Ames, Sosale Chandrasekhar, Kristian J. Hansen   +2 more
openaire   +3 more sources

A Potent New Benzothiadiazine Diuretic

Nature, 1960
SINCE the discovery of chlorothiazide by Beyer et al. 1, a number of chemically related compounds have been shown to possess similar natriuretic and chloruretic actions2–4. Some of these agents, notably 3,4-dihydrochlorothiazide and its derivatives, differ from chlorothiazide primarily in a greater milligram potency, which may be associated with a ...
R M, TAYLOR, M M, WINBURY
openaire   +2 more sources