Results 1 to 10 of about 5,213 (178)
Experimental measurement and thermodynamic modeling of Chlorothiazide solubility in supercritical carbon dioxide [PDF]
Case Studies in Thermal Engineering, 2023 Chlorothiazide, with the brand name Diuril, is used as a diuretic as well as an antihypertensive drug. This medicine with very slight solubility in water and low permeability is categorized in the class IV of Biopharmaceutical Classification System (BCS)
Mohammed Majrashi +2 more
exaly +4 more sources
Case Studies in Thermal Engineering, 2023 Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability.
Ahmad J. Obaidullah
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On the deprotonation of chlorothiazide. [PDF]
Acta Crystallogr C Struct ChemThree alkali metal salt forms of the diuretic chlorothiazide (systematic name: 6‐chloro‐1,1‐dioxo‐2H‐1,2,4‐benzothiazine‐7‐sulfonamide, HCTZ) are described.
Brydson RKH +5 more
europepmc +3 more sources
A monoclinic polymorph of chlorothiazide [PDF]
Acta Crystallographica Section E: Crystallographic CommunicationsA new polymorph of the diuretic chlorothiazide, 6-chloro-1,1-dioxo-2H-1,2,4-benzothiazine-7-sulfonamide, C7H6ClN3O4S2, is described. Crystallized from basic aqueous solution, this monoclinic polymorph is found to be less thermodynamically favoured than ...
Rowan K. H. Brydson, Alan R. Kennedy
doaj +2 more sources
Use of Chlorothiazide in the Management of Central Diabetes Insipidus in Early Infancy
Case Reports in Pediatrics, 2017 Management of central diabetes insipidus in infancy is challenging. The various forms of desmopressin, oral, subcutaneous, and intranasal, have variability in the duration of action.
Manish Raisingani +2 more
doaj +2 more sources
Green HPLC strategy for quantification of carvedilol and hydrochlorothiazide in cardiac medications with in-vitro dissolution kinetics and impurity profiling [PDF]
BMC ChemistryThe introduction of new pharmaceutical formulations necessitates the development of a trustworthy analytical approach capable of quantifying active ingredients in various quality control procedures.
Mona Nabil +4 more
doaj +2 more sources
Severe, late-onset neutropenia associated with prolonged furosemide administration in an extremely preterm infant: a case report and literature review [PDF]
BMC PediatricsBackground Furosemide is commonly used off-label in the neonatal intensive care unit to promote diuresis and improve pulmonary mechanics in preterm infants, but prolonged exposure carries known renal and ototoxic risks and—rarely—hematologic toxicity ...
Ziad W. Elmezayen +4 more
doaj +2 more sources
European Journal of Pharmaceutical Sciences, 2010 Chlorothiazide (CTZ), unlike other thiazide diuretics, can form salts. An injectable formulation containing the sodium salt is available; however neither the physicochemical characteristics of the salt nor its solid state form have been previously ...
Krzysztof J Paluch +2 more
exaly +1 more source
Study of Charge transfer complexes of chlorothiazide [PDF]
Aswan University Journal of Environmental Studies, 2021 The CT-complexes of chlorothiazide (n-donor) with picric acid, 3, 5-dinitrobenzoic acid (pi-acceptor) and iodine (sigma-acceptor) were investigated at different temperatures and solvents.
Asmaa A. Ibrahim +2 more
doaj +1 more source