Case Studies in Thermal Engineering, 2023 Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability.
Ahmad J. Obaidullah
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Case Studies in Thermal Engineering, 2023 Chlorothiazide, with the brand name Diuril, is used as a diuretic as well as an antihypertensive drug. This medicine with very slight solubility in water and low permeability is categorized in the class IV of Biopharmaceutical Classification System (BCS)
Mohammed Majrashi +5 more
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Green HPLC strategy for quantification of carvedilol and hydrochlorothiazide in cardiac medications with in-vitro dissolution kinetics and impurity profiling [PDF]
BMC ChemistryThe introduction of new pharmaceutical formulations necessitates the development of a trustworthy analytical approach capable of quantifying active ingredients in various quality control procedures.
Mona Nabil +4 more
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Diuretic Resistance Treated with Low-Dose Hydralazine: A Case Report and Review of the Literature
Case Reports in Nephrology and Dialysis, 2021 We present a case of severe diuretic resistance and edema from acute cardiorenal syndrome complicating heart failure with preserved ejection fraction (HFpEF) and mild alcoholic liver disease.
Mohammed Alshehri, Christopher Wilcox
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Multifunctional crosslinked chitosan/nitrogen-doped graphene quantum dot for wastewater treatment
Ain Shams Engineering Journal, 2021 The fabrication of multifunctional nanomaterial for the adsorption of different types of pollutants is a challenge and could be a solution for many problems associated with wastewater treatment.
Abdelfattah Amari +6 more
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Decongestive diuresis using combination intravenous loop diuretics plus chlorothiazide in type 1 acute cardiorenal syndrome and worsening acute kidney injury; a neglected paradigm in resource-poor settings [PDF]
Journal of Nephropharmacology, 2020 Over the last decade or more, there has grown a body of evidence demonstrating that renal dysfunction in heart failure is a combination of forward failure from reduced cardiac output and therefore reduced glomerular filtration rate, as well as ...
Macaulay Amechi Chukwukadibia Onuigbo
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Efficacy of pharmacologic therapies in patients with acute heart failure: A network meta-analysis
Frontiers in Pharmacology, 2022 Background: A network meta-analysis (NMA) of the current recommended drugs for the treatment of acute heart failure (AHF), was performed to compare the relative efficacy.Methods: We used PubMed, EMBASE, Cochrane Clinical Trials Register, and Web of ...
Hengheng Dai +7 more
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Diazoxide-responsive hyperinsulinaemic hypoglycaemia in tyrosinaemia type 1
Endocrinology, Diabetes & Metabolism Case Reports, 2021 Tyrosinaemia type 1 (TT1) is a rare inherited disorder of amino acid metabolism typically presenting with liver failure and renal tubular dysfunction. We describe three individuals with TT1 and transient hyperinsulinaemic hypoglycaemia (HH). Two siblings
Ellada Sotiridou +8 more
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Pharmaceutics, 2021 The mechanochemical synthesis of drug–drug solid forms containing metformin hydrochloride (MET·HCl) and thiazide diuretics hydrochlorothiazide (HTZ) or chlorothiazide (CTZ) is reported.
Guadalupe Coyote-Dotor +9 more
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Mechanisms of Diuretic Resistance Study: design and rationale
ESC Heart Failure, 2020 Introduction Diuretic resistance is a common complication impairing decongestion during hospitalization for acute decompensated heart failure (ADHF). The current understanding of diuretic resistance mechanisms in ADHF is based upon extrapolations from ...
Zachary L. Cox +10 more
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