Results 1 to 10 of about 4,839 (140)

Experimental measurement and thermodynamic modeling of Chlorothiazide solubility in supercritical carbon dioxide

Case Studies in Thermal Engineering, 2023
Chlorothiazide, with the brand name Diuril, is used as a diuretic as well as an antihypertensive drug. This medicine with very slight solubility in water and low permeability is categorized in the class IV of Biopharmaceutical Classification System (BCS)
Mohammed Majrashi, Nguyen Le Minh Tri
exaly   +3 more sources

Thermodynamic and experimental analysis of drug nanoparticles preparation using supercritical thermal processing: Solubility of Chlorothiazide in different Co-solvents

Case Studies in Thermal Engineering, 2023
Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability.
Ahmad J. Obaidullah
exaly   +3 more sources

Severe, late-onset neutropenia associated with prolonged furosemide administration in an extremely preterm infant: a case report and literature review [PDF]

BMC Pediatrics
Background Furosemide is commonly used off-label in the neonatal intensive care unit to promote diuresis and improve pulmonary mechanics in preterm infants, but prolonged exposure carries known renal and ototoxic risks and—rarely—hematologic toxicity ...
Ziad W. Elmezayen, Mohammad Adi, Rafeek Walid Elmezayen, He Yunting, Ahmed H. Sharaf   +4 more
doaj   +2 more sources

Neutropenia Associated With Furosemide Administration in a Preterm Infant. [PDF]

Case Rep Pediatr
Furosemide is a commonly used diuretic, though there is scant literature describing its association with leukopenia. We present a case of neutropenia observed in a preterm infant with a congenital heart anomaly, who received both oral and intravenous furosemide over the course of two hospitalizations. Using the Naranjo adverse drug reaction probability
Connolly GK, Keates-Baleeiro J, Curren V, Brady T, Procaccini D, Coulson JD.   +5 more
europepmc   +2 more sources

Green HPLC strategy for quantification of carvedilol and hydrochlorothiazide in cardiac medications with in-vitro dissolution kinetics and impurity profiling [PDF]

BMC Chemistry
The introduction of new pharmaceutical formulations necessitates the development of a trustworthy analytical approach capable of quantifying active ingredients in various quality control procedures.
Mona Nabil, Dina A. Ahmed, Samah S. Abbas, Hayam M. Lotfy, Hoda M. Marzouk   +4 more
doaj   +2 more sources

On the deprotonation of chlorothiazide. [PDF]

Acta Crystallogr C Struct Chem
The structures of the Na and K salt forms of chlorothiazide have been re‐investigated and are found to have different hydration states and deprotonation sites from those described previously. The structure of the Cs salt form is found to contain the same anion as in the new models for the Na and K salt forms.Three alkali metal salt forms of the ...
Brydson RKH, Gray ML, Kennedy AR, O'Hara BC, Reid MW, Ugbolue I.   +5 more
europepmc   +2 more sources

Transdifferentiation of Integrin Beta 1 High+ Skin Progenitor Cells Into Functional Hepatocytes. [PDF]

Stem Cells Int
A highly reproducible and functional liver model that closely resembles the human liver plays a crucial role in drug development, disease research, personalized medicine, and regenerative medicine. This study aimed to establish an in vitro liver model using skin epidermal progenitor cells (EPCs), which are easily accessible and exhibit a high ...
Lim JH, Kim DH, Lee J, Jung CR, Kang HM.
europepmc   +2 more sources

Study of Charge transfer complexes of chlorothiazide [PDF]

Aswan University Journal of Environmental Studies, 2021
The CT-complexes of chlorothiazide (n-donor) with picric acid, 3, 5-dinitrobenzoic acid (pi-acceptor) and iodine (sigma-acceptor) were investigated at different temperatures and solvents.
Asmaa A. Ibrahim, Farouk A. Adam, Ahmed M. Allam   +2 more
doaj   +1 more source

Diuretic Resistance Treated with Low-Dose Hydralazine: A Case Report and Review of the Literature

Case Reports in Nephrology and Dialysis, 2021
We present a case of severe diuretic resistance and edema from acute cardiorenal syndrome complicating heart failure with preserved ejection fraction (HFpEF) and mild alcoholic liver disease.
Mohammed Alshehri, Christopher Wilcox
doaj   +1 more source

Multifunctional crosslinked chitosan/nitrogen-doped graphene quantum dot for wastewater treatment

Ain Shams Engineering Journal, 2021
The fabrication of multifunctional nanomaterial for the adsorption of different types of pollutants is a challenge and could be a solution for many problems associated with wastewater treatment.
Abdelfattah Amari, Noureddine Elboughdiri, Djamel Ghernaout, Ramzi Hadj Lajimi, Ali M. Alshahrani, Mohamed A. Tahoon, Faouzi Ben Rebah   +6 more
doaj   +1 more source