Experimental measurement and thermodynamic modeling of Chlorothiazide solubility in supercritical carbon dioxide [PDF]
Case Studies in Thermal Engineering, 2023 Chlorothiazide, with the brand name Diuril, is used as a diuretic as well as an antihypertensive drug. This medicine with very slight solubility in water and low permeability is categorized in the class IV of Biopharmaceutical Classification System (BCS)
Mohammed Majrashi, Nguyen Le Minh Tri
exaly +4 more sources
Case Studies in Thermal Engineering, 2023 Background/purpose: Chlorothiazide is a well-known diuretic and an antihypertensive drug with poor solubility and permeability and thus low bioavailability.
Ahmad J. Obaidullah
exaly +3 more sources
Single-cell and experimental analyses identify mitochondria-related genes Hmgcs2, Nudt5, and Cpt1c in painful diabetic peripheral neuropathy [PDF]
Scientific ReportsPainful diabetic peripheral neuropathy (PDPN) is a multifactorial disabling complication of diabetes, yet the pathogenesis involving mitochondrial dysfunction in immune cells remains unclear. This study aimed to identify mitochondria-related genes (MRGs)
Jiaqi Cao +5 more
doaj +2 more sources
Severe, late-onset neutropenia associated with prolonged furosemide administration in an extremely preterm infant: a case report and literature review [PDF]
BMC PediatricsBackground Furosemide is commonly used off-label in the neonatal intensive care unit to promote diuresis and improve pulmonary mechanics in preterm infants, but prolonged exposure carries known renal and ototoxic risks and—rarely—hematologic toxicity ...
Ziad W. Elmezayen +4 more
doaj +2 more sources
Green HPLC strategy for quantification of carvedilol and hydrochlorothiazide in cardiac medications with in-vitro dissolution kinetics and impurity profiling [PDF]
BMC ChemistryThe introduction of new pharmaceutical formulations necessitates the development of a trustworthy analytical approach capable of quantifying active ingredients in various quality control procedures.
Mona Nabil +4 more
doaj +2 more sources
Study of Charge transfer complexes of chlorothiazide [PDF]
Aswan University Journal of Environmental Studies, 2021 The CT-complexes of chlorothiazide (n-donor) with picric acid, 3, 5-dinitrobenzoic acid (pi-acceptor) and iodine (sigma-acceptor) were investigated at different temperatures and solvents.
Asmaa A. Ibrahim +2 more
doaj +1 more source
Diuretic Resistance Treated with Low-Dose Hydralazine: A Case Report and Review of the Literature
Case Reports in Nephrology and Dialysis, 2021 We present a case of severe diuretic resistance and edema from acute cardiorenal syndrome complicating heart failure with preserved ejection fraction (HFpEF) and mild alcoholic liver disease.
Mohammed Alshehri, Christopher Wilcox
doaj +1 more source
Multifunctional crosslinked chitosan/nitrogen-doped graphene quantum dot for wastewater treatment
Ain Shams Engineering Journal, 2021 The fabrication of multifunctional nanomaterial for the adsorption of different types of pollutants is a challenge and could be a solution for many problems associated with wastewater treatment.
Abdelfattah Amari +6 more
doaj +1 more source
Decongestive diuresis using combination intravenous loop diuretics plus chlorothiazide in type 1 acute cardiorenal syndrome and worsening acute kidney injury; a neglected paradigm in resource-poor settings [PDF]
Journal of Nephropharmacology, 2020 Over the last decade or more, there has grown a body of evidence demonstrating that renal dysfunction in heart failure is a combination of forward failure from reduced cardiac output and therefore reduced glomerular filtration rate, as well as ...
Macaulay Amechi Chukwukadibia Onuigbo
doaj +1 more source
Efficacy of pharmacologic therapies in patients with acute heart failure: A network meta-analysis
Frontiers in Pharmacology, 2022 Background: A network meta-analysis (NMA) of the current recommended drugs for the treatment of acute heart failure (AHF), was performed to compare the relative efficacy.Methods: We used PubMed, EMBASE, Cochrane Clinical Trials Register, and Web of ...
Hengheng Dai +7 more
doaj +1 more source