Results 41 to 50 of about 5,213 (178)

Early in‐hospital treatment of acute heart failure. Part 2 of the international expert opinion series on AHF management

ESC Heart Failure, Volume 12, Issue 6, Page 3826-3843, December 2025.
This state‐of‐the‐art review outlines a practical, evidence‐based framework for early acute heart failure management to address critical gaps in current guidance and improve early treatment outcomes. Key components include early identification of co‐existing conditions, bedside haemodynamic profiling, a structured diagnostic approach incorporating both
Anika S. Naidu, Andrew P. Ambrosy, Gad Cotter, Edimar A. Bocchi, Javed Butler, Ovidiu Chioncel, Beth Davison, Anastase Dzudie, Yonathan Freund, Marat Fudim, Sivadasanpillai Harikrishnan, Ivna G. Cunha, Alexandre Mebazaa, Robert J. Mentz, Òscar Miró, Siti E. Nauli, Mateo Pagnesi, Naoki Sato, Gianluigi Savarese, Karen Sliwa‐Hahnle, Yuhui Zhang, Jingmin Zhou, Jan Biegus   +22 more
wiley   +1 more source

Effects of Chlorothiazide on Muscarinic Receptors

, 2012
Chlorothiazide (6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide) is diuretic drug normally used within a hospital setting to manage excess fluid associated with congestive heart failure and as an antihypertensive drug.
Bey, Katie
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Experimental and predicted crystal energy landscapes of chlorothiazide

, 2011
An experimental search for physical forms of the thiazide diuretic compound chlorothiazide comprising 402 different crystallizations identified one nonsolvated form and ten crystalline solvates.
Sarah L. Price, Kennedy, Alan, Price, Sarah L., Blair F. Johnston, Julie Bardin, Johnston, Andrea, Florence, Alastair, Johnston, Blair, Alan R. Kennedy, Bardin, Julie, Andrea Johnston, Fernandes, Phillippe, Philippe Fernandes, Alastair J. Florence   +13 more
core   +1 more source

A Review of Global Optimization Methods for Molecular Structures: Algorithms, Applications and Perspectives

Journal of Computational Chemistry, Volume 46, Issue 28, October 30, 2025.
This image categorizes global optimization methods into stochastic and deterministic approaches. Stochastic methods include techniques like Genetic Algorithms, Simulated Annealing, and Machine Learning, often involving randomness. Deterministic methods, such as Molecular Dynamics and Single‐Ended methods, follow defined rules without randomness.
Jorge Alberto Sanchez Alvarez, Patrizia Calaminici   +1 more
wiley   +1 more source

A good‐practice guide to solving and refining molecular organic crystal structures from laboratory powder X‐ray diffraction data

Acta Crystallographica Section C, Volume 81, Issue 10, Page 559-569, October 2025.
A step‐by‐step outline for academic and industrial practitioners determining molecular organic crystal structures from powder X‐ray diffraction data.This article focuses on a specific real‐space methodology for solving and refining molecular organic crystal structures, developed by the authors and collaborators.
Elena Kabova, Margarita Mersiyanova, Kenneth Shankland, Norman Shankland, Mark Spillman   +4 more
wiley   +1 more source

Effect of chlorothiazide on electrolyte excretion in intact and adrenalectomized rats

, 1962
The acute effects of the oral administration of chlorothiazide on electrolyte and water excretion were studied in adrenalectomized and intact male Sprague-Dawley rats.
Melvin Kahn
core   +1 more source

Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics—A Population‐Level Case‐Control Study

Otolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 613-625, September 2025.
Abstract Objective This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population‐level database. Study Design A case‐control study. Setting TriNetX US Collaborative Network. Methods Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18 ...
Marwin Li, Rebecca C. Chiffer, Hongyan Li   +2 more
wiley   +1 more source

Effect of potassium deficiency on action of chlorothiazide in the rat

, 1963
Chlorothiazide was administered to male rats which had been fed a potassium-deficient diet, and also to their pair-fed controls. Daily urine collections were carried out on the experimental and control rats before and during chlorothiazide ...
Ashton B. Morrison
core   +1 more source

Effect of angiotensin II-induced changes in perfusion flow rate on chlorothiazide transport in the isolated perfused rat kidney [PDF]

, 1992
Angiotensin II was used as a probe to study the effect of changes in perfusate flow rate on the renal clearance parameters of chlorothiazide in the isolated perfused rat kidney. Perfusion studies were performed in five rats with no angiotensin II present
Guillard, Stephanie, Carlos A. Rodriguez, David E. Smith, Stephanie Guillard, Rodriguez, Carlos A., Smith, David E.   +5 more
core   +1 more source