Results 21 to 30 of about 9,127 (231)

Thiazides in advanced chronic kidney disease—time for a randomized controlled trial? [PDF]

, 2015
Purpose of review: Chronic kidney disease is common, associated with increased cardiovascular risk, and frequently complicated by hypertension, requiring multiple agents for control.
Agarwal, Rajiv, Sinha, Arjun D.
core   +1 more source

An eco-friendly separation-based framework for quantitative determination and purity testing of an antihypertensive ternary pharmaceutical formulation

BMC Chemistry, 2023
Designing new, verified methodologies with a focus on sustainability, analytical efficiency, simplicity, and the environment has become a major priority for pharmaceutical quality control units.
Hoda M. Marzouk, Nada S. Ayish, Badr A. El-Zeany, Ahmed S. Fayed   +3 more
doaj   +1 more source

Hyponatraemia and hypokalaemia due to indapamide [PDF]

, 2002
The document attached has been archived with permission from the editor of the Medical Journal of Australia (10 January 2008). An external link to the publisher’s copy is included.Objectives: To review Australian adverse drug reaction reports describing ...
Chapman, M., Hanrahan, R., Marley, J., McEwen, J.   +3 more
core   +1 more source

Sustainable chromatographic quantitation of multi-antihypertensive medications: application on diverse combinations containing hydrochlorothiazide along with LC–MS/MS profiling of potential impurities: greenness and whiteness evaluation

BMC Chemistry, 2023
Cardiovascular disorders are among the leading causes of death worldwide, especially hypertension, a silent killer syndrome requiring multiple drug therapy for appropriate management.
Hoda M. Marzouk, Sara El-Hanboushy, Reem H. Obaydo, Yasmin M. Fayez, Mohamed Abdelkawy, Hayam M. Lotfy   +5 more
doaj   +1 more source

Impact of process variables on the micromeritic and physicochemical properties of spray-dried porous microparticles, part I: introduction of a new morphology classification system [PDF]

, 2012
YesObjectives This work investigated the impact of spray drying variables such as feedconcentration, solvent composition and the drying mode, on the micromeriticproperties of chlorothiazide sodium (CTZNa) and chlorothiazide potassium(CTZK).Methods ...
Amaro, Anne Marie Healy, Carretero, Dellamary, Goula, Gregg, Healy, Hilfiker, Hirst, Korhonen, Krzysztof J. Paluch, Leong, Lidia Tajber, Masters, Nolan, Nolan, NíÓgáin, Owen I. Corrigan, Paluch, Paluch, Paluch, Steinhaus, Tajber, Takeuchi, Vehring, Walton   +25 more
core   +1 more source

Comparative study of Two In Vitro Methods for Assessing Drug Absorption: Sartorius SM 16750 Apparatus Versus Everted Gut Sac

Journal of Pharmacy & Pharmaceutical Sciences, 2011
– Purpose. Oral drug administration remains the most common and most convenient way used in clinical therapy. The availability of a simple, rapid, economic and reproducible in vitro method to assess drug absorption is a very helpful tool.
Mohamed Ali Lassoued, Fathia Khemiss, Souad Sfar   +2 more
doaj   +1 more source

Transdifferentiation of Integrin Beta 1 High+ Skin Progenitor Cells Into Functional Hepatocytes. [PDF]

Stem Cells Int
A highly reproducible and functional liver model that closely resembles the human liver plays a crucial role in drug development, disease research, personalized medicine, and regenerative medicine. This study aimed to establish an in vitro liver model using skin epidermal progenitor cells (EPCs), which are easily accessible and exhibit a high ...
Lim JH, Kim DH, Lee J, Jung CR, Kang HM.
europepmc   +2 more sources

A novel approach to crystallisation of nanodispersible microparticles by spray drying for improved tabletability [PDF]

, 2012
YesHigh-dose API powders which are to be tableted by direct compression should have high compactibility and compressibility. This note reports on a novel approach to the manufacture of crystalline powders intended for direct compaction with improved ...
Adamczyk, B., Corrigan, O.I., Healy, A.M., Paluch, Krzysztof J., Tajber, L.   +4 more
core   +1 more source

Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair [PDF]

, 2015
A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, with consequent loss of ...
Olson, Eric N., van Rooij, Eva
core   +1 more source

Renal magnesium handling: New insights in understanding old problems [PDF]

, 1997
Many sharp-eyed readers have pointed out to us that in the photo next to the article about yams in Ghana (Spore 87, June 2000, page 8), the woman had put all her cassava in one basket, and not the yams she planned to use. Point taken.
Gary A. Quamme, Quamme, de Rouffignac, de Rouffignac, le Grimellec, de Rouffignac, le Grimellec, Quamme, Quamme, Quamme, Poujeol, Wong, Leliévre-Pegorier, Simon, Simon, Simon, Mandon, Di Stefano, Shareghi, Wittner, Di Stefano, Di Stefano, Mandon, Wittner, Wittner, Dai, Bailly, Elalouf, Elalouf, Quamme, Quamme, Dai, Dai, Quamme, Li, Li, Quamme, Pizzonia, Friedman, Shafik, Günther, Auger, Bailly, Bailly, Elalouf, Poujeol, de Rouffignac, Wittner, Bailly, Reeves, Stanton, Work, Bailly, Chabardés, Morel, Morel, Dai, Greger, Reeves, Suki, Massry, Massry, Suki, Friedman, Bouhtiauy, Hilal, Rossier, Jackson, Rajerison, Doucet, El Mernissi, De Rouffignac, Ahloulay, Di Stefano, Quamme, Brown, Brown, Riccardi, Riccardi, Hebert, Wang, Ye, Sands, Massry, Rude, Bapty, Bapty, Estep, Pollak, Attie, Law, Kristiansen, Marx, Pollak, Pollak, Ho, Pearce, Dunn, Shils, Al-Ghamdi, Di Stefano, Quamme, Gullestad, Rude, Elin, Niemela, Quamme, Hedemann, Praga, Challa, Geven, Griffin, Iwata, Walder, Geven, Bundy, Clauw, Nicholson, Prebble, Rodriguez-Soriano, Torrolbo, Richard, Ritchie, Douban, Devane, Friedman, Murdoch, Wester, Hollifield, Gesek, Stanton, Kroenke, Paolisso, Saito, Siegel, Duarte, Lemann, Wu, Lennon, Peraino, Shapiro, Levin, Wong, Dai, Pietrobon, Chen, Mather, McNair, Tosiello, Eknoyan, Gutsche, Luke, Luke, Bartter, Gitelman, Cushner, Stein, Simon, Scoble, Betthinelli, Zarlaga Larronndo, Colussi, Coburn, Domingues, Kreusser, Wong, Dai, Crook, Krishna   +168 more
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