Results 11 to 20 of about 4,839 (140)
Decongestive diuresis using combination intravenous loop diuretics plus chlorothiazide in type 1 acute cardiorenal syndrome and worsening acute kidney injury; a neglected paradigm in resource-poor settings [PDF]
Journal of Nephropharmacology, 2020 Over the last decade or more, there has grown a body of evidence demonstrating that renal dysfunction in heart failure is a combination of forward failure from reduced cardiac output and therefore reduced glomerular filtration rate, as well as ...
Macaulay Amechi Chukwukadibia Onuigbo
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Efficacy of pharmacologic therapies in patients with acute heart failure: A network meta-analysis
Frontiers in Pharmacology, 2022 Background: A network meta-analysis (NMA) of the current recommended drugs for the treatment of acute heart failure (AHF), was performed to compare the relative efficacy.Methods: We used PubMed, EMBASE, Cochrane Clinical Trials Register, and Web of ...
Hengheng Dai +7 more
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Diazoxide-responsive hyperinsulinaemic hypoglycaemia in tyrosinaemia type 1
Endocrinology, Diabetes & Metabolism Case Reports, 2021 Tyrosinaemia type 1 (TT1) is a rare inherited disorder of amino acid metabolism typically presenting with liver failure and renal tubular dysfunction. We describe three individuals with TT1 and transient hyperinsulinaemic hypoglycaemia (HH). Two siblings
Ellada Sotiridou +8 more
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Pharmaceutics, 2021 The mechanochemical synthesis of drug–drug solid forms containing metformin hydrochloride (MET·HCl) and thiazide diuretics hydrochlorothiazide (HTZ) or chlorothiazide (CTZ) is reported.
Guadalupe Coyote-Dotor +9 more
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Mechanisms of Diuretic Resistance Study: design and rationale
ESC Heart Failure, 2020 Introduction Diuretic resistance is a common complication impairing decongestion during hospitalization for acute decompensated heart failure (ADHF). The current understanding of diuretic resistance mechanisms in ADHF is based upon extrapolations from ...
Zachary L. Cox +10 more
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BMC Chemistry, 2023 Designing new, verified methodologies with a focus on sustainability, analytical efficiency, simplicity, and the environment has become a major priority for pharmaceutical quality control units.
Hoda M. Marzouk +3 more
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Journal of Pharmacy & Pharmaceutical Sciences, 2011 – Purpose. Oral drug administration remains the most common and most convenient way used in clinical therapy. The availability of a simple, rapid, economic and reproducible in vitro method to assess drug absorption is a very helpful tool.
Mohamed Ali Lassoued +2 more
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BMC Chemistry, 2023 Cardiovascular disorders are among the leading causes of death worldwide, especially hypertension, a silent killer syndrome requiring multiple drug therapy for appropriate management.
Hoda M. Marzouk +5 more
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Use of Chlorothiazide in the Management of Central Diabetes Insipidus in Early Infancy
Case Reports in Pediatrics, 2017 Management of central diabetes insipidus in infancy is challenging. The various forms of desmopressin, oral, subcutaneous, and intranasal, have variability in the duration of action.
Manish Raisingani +2 more
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FGF23 regulates renal sodium handling and blood pressure
EMBO Molecular Medicine, 2014 Fibroblast growth factor‐23 (FGF23) is a bone‐derived hormone regulating renal phosphate reabsorption and vitamin D synthesis in renal proximal tubules. Here, we show that FGF23 directly regulates the membrane abundance of the Na+:Cl− co‐transporter NCC ...
Olena Andrukhova +7 more
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