Results 151 to 160 of about 1,553 (193)

Antihypertensive Medications and Risk of Melanoma and Keratinocyte Carcinomas: A Systematic Review and Meta-Analysis. [PDF]

JID Innov
Cohen OG, Taylor M, Mohr C, Nead KT, Hinkston CL, Giordano SH, Langan SM, Margolis DJ, Wehner MR.   +8 more
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Current Concepts in Therapy: Antihypertensive Agents. II. Benzothiadiazine Compounds, Rauwolfia and Hydralazine

, 1962
Edward D. Freis
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[Thin-layer chromatography of benzothiadiazine derivatives].

Acta poloniae pharmaceutica, 1966
Z, Margasiński, R, Danielak, H, Rafalowska   +2 more
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Some 1H-4,1,2-benzothiadiazines and 1H-4,1,2-benzothiadiazine 4,4-dioxides

Journal of the Chemical Society, Perkin Transactions 1, 1978
Interamolecular displacement of the o-nitro-group of 1-(2-nitrophenylthio)pyruvaldehyde 1-phenylhydrazone, under basic conditions, gives 3-acetyl-1-phenyl-1H-4,1,2-benzothiadiazine which was oxidised to the 4,4-dioxide. Ethyl 2-nitrophenylsulphonylglyoxylate phenylhydrazone gives only 2-nitrodiphenylamine under these conditions, but reduction to the 2 ...
Donald E. Ames, Sosale Chandrasekhar, Kristian J. Hansen   +2 more
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Hydrolysis of Benzothiadiazines

Journal of Pharmaceutical Sciences, 1971
The hydrolysis of hydrochlorothiazide and two other hydrothiazides was studied as a function of pH. Reversible kinetics were observed for the hydrolytic reaction, and a bell-shaped pH-rate profile was obtained. The equilibrium constant, however, was relatively independent of hydrogen-ion concentration.
J A, Mollica, C R, Rehm, J B, Smith, H K, Govan   +3 more
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A Potent New Benzothiadiazine Diuretic

Nature, 1960
SINCE the discovery of chlorothiazide by Beyer et al. 1, a number of chemically related compounds have been shown to possess similar natriuretic and chloruretic actions2–4. Some of these agents, notably 3,4-dihydrochlorothiazide and its derivatives, differ from chlorothiazide primarily in a greater milligram potency, which may be associated with a ...
R M, TAYLOR, M M, WINBURY
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Copper-promoted aerial oxidation of benzothiadiazines: access to benzothiadiazine S-oxide heterocycles

Dalton Transactions, 2015
Aerial oxidation of benzothiadiazines selectively affords the corresponding benzothiadiazine S-oxides in the presence of Cu2+ ions. Structural studies reveal that the S-oxide appears to be a strong hydrogen-bond acceptor.
Ewan R, Clark, John J, Hayward, Bryce J, Leontowicz, Muhammad U, Anwar, Melanie, Pilkington, Jeremy M, Rawson   +5 more
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ChemInform Abstract: SYNTHESES OF 1,2,4‐BENZOTHIADIAZINE 1‐OXIDES AND 1,2,4‐BENZOTHIADIAZINES

Chemischer Informationsdienst, 1981
AbstractAus den Anilino‐sulfonylchloriden (I) entstehen mit Natriumsulfit die Sulfinsäuren (II), die mit Thionylchlorid und Aminen (III) zu den Sulfinsäureamiden (IV) führen.
N. FINCH, S. JUN. RICCA, L. H. WERNER, R. RODEBAUGH   +3 more
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Hypotensive Activity of Two Benzothiadiazine Derivatives

Journal of Pharmaceutical Sciences, 1965
4-Hydrazino-1,2,3-benzothiadiazine-1,1 dioxide hydrochloride (EX 4211A) and 6-chloro-3,4-dihydro-3-( β -oxo- n -propyl)-7-sulfamyl-2H-1,2,4-benzothiadiazine 1,1-dioxide phthalazone azine (EX 5004) were studied in the rat and dog to elucidate the mechanism(s) by which these compounds produced hypotensive effects.
A I, EDLIN, W J, KINNARD, E E, VOGIN, J P, BUCKLEY   +3 more
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Structural studies on benzothiadiazine derivatives: 3-amino-4H-1,2,4-benzothiadiazine 1,1-dioxide and 3-hydrazino-4H-1,2,4-benzothiadiazine 1,1-dioxide

Acta Crystallographica Section C Crystal Structure Communications, 1989
C 7 H 7 N 3 O 2 S (1) cristallise dans Cc avec a=14,259, b=22,539 et c=8,741 A, β=114,10 o , Z=12; affinement jusqu'a R=0,040. C 7 H 8 N 4 O 2 S (2) cristallise dans P2 1 /n avec a=6,976, b=8,403 et c=14,748 A, β=90,25 o , Z=4; affinement jusqu'a R=0,042.
G. Bombieri, F. Demartin, D. Braghiroli, S. Todeschi, M. Di Bella   +4 more
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