Results 51 to 60 of about 31,532 (196)
Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides
Advanced Science, EarlyView.This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das +13 more
wiley +1 more source
Improving Productivity of Multiphase Flow Aerobic Oxidation Using a Tube-in-Tube Membrane Contactor [PDF]
, 2019 The application of flow reactors in multiphase catalytic reactions represents a promising approach for enhancing the efficiency of this important class of chemical reactions.
Burkholder, Michael +4 more
core +1 more source
Advanced Science, EarlyView.We report a general strategy for meta‐selective C–H arylation using aryl iodides and a Pd(II)/Pd(IV) catalytic system guided by a removable directing group. DFT and experimental studies reveal that counter anion tuning (acetate to trifluoroacetate) significantly enhances selectivity.
Jagrit Grover +6 more
wiley +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Advanced Science, EarlyView.Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
Regioselective trans-Carboboration of Propargyl Alcohols
, 2019 Proper choice of the base allowed trans-diboration of propargyl alcohols with B2(pin)2 to evolve into an exquisitely regioselective procedure for net trans-carboboration.
Fürstner, A., Jin, H.
core +1 more source
Effect of plasma lipids, hypertension and APOE genotype on cognitive decline [PDF]
, 2012 We examined the combined effect of plasma lipids/hypertension and apolipoprotein E (APOE) genotype on cognitive function in elderly individuals. Plasma concentrations of high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride (TG ...
Asada Takashi +12 more
core +1 more source
Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update
Advanced Science, EarlyView.This review explores recent advances in the past five years for non‐traditional RAFT polymerization, focusing on new activation strategies, sustainable depolymerization, and integration with automated and AI‐driven synthesis. Together, these innovations advance polymer chemistry and reveal how the pieces of the non‐traditional RAFT puzzle are steadily ...
Vianna F. Jafari +10 more
wiley +1 more source
A Noncovalent Click‐to‐Release Strategy to Control Bond Cleavage and Prodrug Activation
Angewandte Chemie, EarlyView.Extending the click‐to‐release concept beyond covalent ligation, we introduce a noncovalent click‐to‐release strategy based on cucurbituril‐adamantane (CB‐Ad) association. A supramolecular preassembly encapsulating a self‐immolative guest (SIG) is rationally designed to prevent premature release, while adding a high‐affinity Ad guest initiates the CB ...
Xuancheng Fu +9 more
wiley +2 more sources
Recent progress in the synthesis of six-membered aminocyclitols (2008-2017) [PDF]
, 2018 Aminocyclitols are of interest as glucosidase inhibitors, as probes for the study of pseudoglycosyltransferases, and as potential therapeutics for the treatment of Gaucher’s disease.
Donaldson, William
core +1 more source
Highly Cooperative Tetrametallic Ruthenium-μ-Oxo-μ-Hydroxo Catalyst for the Alcohol Oxidation Reaction [PDF]
, 2006 The tetrametallic ruthenium-oxo-hydroxo-hydride complex {[(PCy3)(CO)RuH]4(μ4-O)(μ3-OH)(μ2-OH)} (1) was synthesized in two steps from the monomeric complex (PCy3)(CO)RuHCl (2).
Guzei, Ilia A. +2 more
core +2 more sources