Results 61 to 70 of about 31,532 (196)

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +2 more sources

2-Diazoacetoacetic acid, an efficient and convenient reagent for the synthesis of alpha-diazo-beta-ketoesters [PDF]

, 2006
The formation of various alpha-diazo acetoacetic esters can be obtained in a single transformation with good to excellent yields using readily available 2-diazoacetoacetic ...
Ferreira, Eric M., Meyer, Michael E., Stoltz, Brian M.   +2 more
core  

Expanding the Chemical Space of Cyclic Polyphthalaldehyde via Post‐Functionalization

Advanced Science, EarlyView.
In this work, we developed a post‐functionalization approach to achieve water‐soluble cyclic polyphthalaldehyde (cPPA) polymers via click chemistry. ABSTRACT Cyclic polyphthalaldehydes (cPPAs) are hydrophobic cyclic polymers with stimuli‐responsive depolymerization property. The introduction of hydrophilic functionalities to cPPAs is challenging due to
Liting He, Haiyan Zhou, Qiushi Chen, Xing Guo, Han Liu, Xuechen Li   +5 more
wiley   +1 more source

Molecular‐Scale Tuning of Low‐Molecular‐Weight Gelators Controls Supramolecular Assembly and Directs Human Mesenchymal Stem Cell Growth

Angewandte Chemie, EarlyView.
Chemistry in charge of biology! Simple low‐molecular‐weight gelators, with minor modifications in molecular structure, self‐assemble differently and can also co‐assemble when simultaneously triggered. This creates a family of gels with different properties that direct the growth of stem cells in different ways.
Chayanan Tangsombun, Amy Simpson, Rebecca L. Charlton, Lucy E. Sabin, Paul G. Genever, David K. Smith   +5 more
wiley   +2 more sources

A Polymer‐Intercalated Modulation Assembly Strategy Towards Mesoporous Single‐Crystalline BiVO4 Materials for Enhanced Photocatalytic Performance

Advanced Science, EarlyView.
A polymer‐intercalated modulation assembly strategy was proposed to synthesize mesoporous single‐crystalline BiVO4 with tunable pore structure by co‐assembly of inorganic–organic composite through coordination bonds and hydrogen bonds. Thanks to single‐crystalline properties and mesoporous structure with vanadium vacancy microenvironment, the prepared ...
Wei Li, Xiaoyan Wei, Yumeng Mao, Zhengwen Tan, Wenjun Duan, Ling Zhang, Zhen‐An Qiao   +6 more
wiley   +1 more source

Mild Generation of Highly Nucleophilic N‐Heterocyclic Carbene Boryl Anion From Neutral sp2–sp3 Diboron Reagents and Its Applications in Nucleophilic Borylation

Angewandte Chemie, EarlyView.
A less hindered and highly nucleophilic N‐heterocyclic carbene (NHC) boryl anion is generated at room temperature by reacting sp2–sp3 diboron reagent (NHC)BH2Bpin with KOtBu. This highly reactive anion demonstrates broad reactivity with various electrophiles, including those traditionally considered inert, enabling their efficient borylation.
Weixuan Sun, Peiqi Zhang, Hairong Lyu
wiley   +2 more sources

Electrochemical Nitrate Reduction Reaction to Ammonia at Industrial‐Level Current Densities

Advanced Science, EarlyView.
This review starts from the mechanism and theoretical basis of electrochemical nitrate reduction reaction (NO3−RR), and systematically summarizes and discusses the design strategies of industrial‐level current density catalysts. In addition, the progress of industrial‐level NO3−RR‐based electrolyzers, including flow reactor and membrane electrode ...
Zhijie Cui, Honghai Wang, Chunli Li, Wenchao Peng, Jiapeng Liu   +4 more
wiley   +1 more source

Enantioselective Reductive Alkenylation of α‐CF2H (‐CF3) Amino Halides: Rapid Access to Chiral α‐CF2H (‐CF3) Allylamines

Advanced Science, EarlyView.
Difluoromethyl (CF2H) group, the bioisostere of hydroxyl thiol methyl or amide is privileged in medicinal chemistry due to hydrogen‐binding ability and lipophilic, metabolically stable, and chemical inert nature. However, enatioseleceive CF2H introduction remains challenging.
Peng Liu, Kuiliang Li, Yan He, Chen‐Hui Jiang, Ruo‐Xing Jin, Duo‐Duo Hu, Wei‐Cheng Zhao, Xuan Nie, Shang‐Zheng Sun, Xi‐Sheng Wang   +9 more
wiley   +1 more source

Anti-fog composition [PDF]

, 1974
An anti-fog composition is described for the prevention of fogging on surfaces such as space helmet visors, spacecraft windows, and windshields.
Carmin, D. L., Jr., Morrison, H. D.
core   +1 more source