Benzyl isothiocyanate ameliorates cognitive function in mice of chronic temporal lobe epilepsy [PDF]
Frontiers in NeurologyObjectiveTemporal lobe epilepsy (TLE) is a prevalent refractory partial epilepsy seen in clinical practice, with most cases originating from the hippocampus and being characterized by impaired learning and memory.
Chang Xiaoyu +15 more
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Nephroprotective Effects of Benzyl Isothiocyanate and Resveratrol Against Cisplatin-Induced Oxidative Stress and Inflammation [PDF]
Frontiers in Pharmacology, 2018 This study was performed to compare the nephroprotective effects of benzyl isothiocyanate (BITC) and resveratrol (RES) and investigate the nephroprotective efficacy of their combination against cisplatin-induced acute renal injury.
Abdelazim Ibrahim +4 more
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Antimalarial Activity of Aqueous Extracts of Nasturtium (Tropaeolum majus L.) and Benzyl Isothiocyanate [PDF]
MoleculesMalaria remains an important and challenging infectious disease, and novel antimalarials are required. Benzyl isothiocyanate (BITC), the main breakdown product of benzyl glucosinolate, is present in all parts of Tropaeolum majus L. (T.
Ana Maria Pintão +2 more
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Benzyl isothiocyanate provokes senolysis by targeting AKT in senescent IPF fibroblasts and reverses persistent pulmonary fibrosis in aged mice [PDF]
Frontiers in PharmacologyIntroductionSenescent cells (SCs) accumulate with age and play a causative role in age-related diseases, such as idiopathic pulmonary fibrosis (IPF). Clearance of SCs attenuates lung fibrogenesis and favors fibrosis resolution, suggesting that targeting ...
Rui Wang +9 more
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Benzyl isothiocyanate suppresses development of thyroid carcinoma by regulating both autophagy and apoptosis pathway [PDF]
iScienceSummary: Anaplastic thyroid carcinoma (ATC) is the most aggressive type of thyroid cancer, characterized by rapid growth and invasion and poor prognosis.
Rossella Basilotta +11 more
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Pharmacological ResearchIn recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects.
Cosima C. Hoch +8 more
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Phytochemical Profiling by UHPLC–Q-TOF/MS and Chemopreventive Effect of Aqueous Extract of Moringa oleifera Leaves and Benzyl Isothiocyanate on Murine Mammary Carcinogenesis [PDF]
MoleculesMoringa oleifera Lam, commonly known as moringa, is a plant widely used both as a human food and for medicinal purposes around the world. This research aimed to evaluate the efficacy of the aqueous extract of Moringa oleifera leaves (MoAE) and benzyl ...
Juan Pedro Rojas-Armas +8 more
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Croatian Journal of Food Science and Technology, 2021 Tropaeolum majus L. is an annual herbaceous plant and a member of the Tropaeolaceae family, which belongs to the Brassicales order. It is an excellent source of flavonoids, carotenoids, phenolic acids, vitamin C, and it is a plant that contains the ...
Ivana Vrca +4 more
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Bacterial Degradation of Benzyl Isothiocyanate [PDF]
Applied Microbiology, 1972 Bacteria that degrade benzyl isothiocyanate to benzylamine and hydrogen sulfide were isolated from papaya pulp homogenate by enrichment culture techniques. These organisms were identified as members of Enterobacter cloacae .
C S, Tang, K, Bhothipaksa, H A, Frank
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Antioxidants, 2021 Malignant melanoma is one of the most deadly types of solid cancers, a property mainly attributed to its highly aggressive metastatic form. On the other hand, different classes of isothiocyanates, a class of phytochemicals, present in cruciferous ...
Melina Mitsiogianni +7 more
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