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Antimalarial Activity of Aqueous Extracts of Nasturtium (Tropaeolum majus L.) and Benzyl Isothiocyanate [PDF]
MoleculesMalaria remains an important and challenging infectious disease, and novel antimalarials are required. Benzyl isothiocyanate (BITC), the main breakdown product of benzyl glucosinolate, is present in all parts of Tropaeolum majus L. (T.
Ana Maria Pintão +2 more
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Benzyl isothiocyanate provokes senolysis by targeting AKT in senescent IPF fibroblasts and reverses persistent pulmonary fibrosis in aged mice [PDF]
Frontiers in PharmacologyIntroductionSenescent cells (SCs) accumulate with age and play a causative role in age-related diseases, such as idiopathic pulmonary fibrosis (IPF). Clearance of SCs attenuates lung fibrogenesis and favors fibrosis resolution, suggesting that targeting ...
Rui Wang +9 more
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Pharmacological ResearchIn recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects.
Cosima C. Hoch +8 more
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Molecules, 2003 3-Aryl-2-chloropropylisothiocyanates (1) are formed by interaction of arenediazonium chlorides with allyl isothiocyanate. Adducts 1 react with monoacylhydrazines to form 1-acyl-4-(3-aryl-2-chloropropyl)thiosemicarbazides (2a–d).
Mykola I. Ganushchak +2 more
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Modulation of Carcinogen Metabolism by Benzyl Isothiocyanate.
, 2008 Precision-cut rat liver slices were incubated with various concentrations of benzyl isothiocyanate (BITC) (0-25 uM) for 24 hours. BITC decreased the dealkylation of ethoxy-(EROD) and methoxyresorufin (MROD) but increased CYP1A1/2 apoprotein levels; in vitro studies confirmed that it is mechanism-based inhibitor.
Arya, Nlin., Arya, Nlin
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Croatian Journal of Food Science and Technology, 2021 Tropaeolum majus L. is an annual herbaceous plant and a member of the Tropaeolaceae family, which belongs to the Brassicales order. It is an excellent source of flavonoids, carotenoids, phenolic acids, vitamin C, and it is a plant that contains the ...
Ivana Vrca +4 more
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Bacterial Degradation of Benzyl Isothiocyanate [PDF]
Applied Microbiology, 1972 Bacteria that degrade benzyl isothiocyanate to benzylamine and hydrogen sulfide were isolated from papaya pulp homogenate by enrichment culture techniques. These organisms were identified as members of Enterobacter cloacae .
C S, Tang, K, Bhothipaksa, H A, Frank
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Antioxidants, 2021 Malignant melanoma is one of the most deadly types of solid cancers, a property mainly attributed to its highly aggressive metastatic form. On the other hand, different classes of isothiocyanates, a class of phytochemicals, present in cruciferous ...
Melina Mitsiogianni +7 more
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Bioactivity of brassica seed meals and its compounds as ecofriendly larvicides against mosquitoes
Scientific Reports, 2023 Strategic, sustainable, and ecofriendly alternatives to chemical pesticides are needed to effectively control mosquitoes and reduce the incidence of their vectored diseases.
Lina B. Flor-Weiler +6 more
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Toxins, 2022 Aflatoxins (AFs), a class of toxins produced by certain species of the genus Aspergillus, occasionally contaminate food and cause serious damage to human health and the economy.
Yohei Hareyama +5 more
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