Results 21 to 30 of about 8,965 (194)
Benzyl isothiocyanate provokes senolysis by targeting AKT in senescent IPF fibroblasts and reverses persistent pulmonary fibrosis in aged mice [PDF]
Frontiers in PharmacologyIntroductionSenescent cells (SCs) accumulate with age and play a causative role in age-related diseases, such as idiopathic pulmonary fibrosis (IPF). Clearance of SCs attenuates lung fibrogenesis and favors fibrosis resolution, suggesting that targeting ...
Rui Wang +9 more
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Molecules, 2003 3-Aryl-2-chloropropylisothiocyanates (1) are formed by interaction of arenediazonium chlorides with allyl isothiocyanate. Adducts 1 react with monoacylhydrazines to form 1-acyl-4-(3-aryl-2-chloropropyl)thiosemicarbazides (2a–d).
Mykola I. Ganushchak +2 more
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Benzyl isothiocyanate suppresses development of thyroid carcinoma by regulating both autophagy and apoptosis pathway [PDF]
iScienceSummary: Anaplastic thyroid carcinoma (ATC) is the most aggressive type of thyroid cancer, characterized by rapid growth and invasion and poor prognosis.
Rossella Basilotta +11 more
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Pharmacological ResearchIn recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects.
Cosima C. Hoch +8 more
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ynthesis and Characterization of 1-Aryl-5-hepta-O-acetyl-β-D-maltosyl-2-S-benzyl-2,4-isodithiobiurets [PDF]
E-Journal of Chemistry, 2012 The facile synthesis of 1-aryl-5-hepta-o-acetyl-β-D-maltosyl-2-S-benzyl-2,4-isodithiobiurets (IIIa-g) has been achieved by the interaction of 1-hepta-O-acetyl-β–D-maltosyl isothiocyanate (I) with various1-aryl-S-benzyl isothiocarbamides (IIa-g). All the
R. D. Ghuge, S. P. Deshmukh
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Phytochemical Profiling by UHPLC–Q-TOF/MS and Chemopreventive Effect of Aqueous Extract of Moringa oleifera Leaves and Benzyl Isothiocyanate on Murine Mammary Carcinogenesis [PDF]
MoleculesMoringa oleifera Lam, commonly known as moringa, is a plant widely used both as a human food and for medicinal purposes around the world. This research aimed to evaluate the efficacy of the aqueous extract of Moringa oleifera leaves (MoAE) and benzyl ...
Juan Pedro Rojas-Armas +8 more
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Modulation of Carcinogen Metabolism by Benzyl Isothiocyanate.
, 2008 Precision-cut rat liver slices were incubated with various concentrations of benzyl isothiocyanate (BITC) (0-25 uM) for 24 hours. BITC decreased the dealkylation of ethoxy-(EROD) and methoxyresorufin (MROD) but increased CYP1A1/2 apoprotein levels; in vitro studies confirmed that it is mechanism-based inhibitor.
Arya, Nlin., Arya, Nlin
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Croatian Journal of Food Science and Technology, 2021 Tropaeolum majus L. is an annual herbaceous plant and a member of the Tropaeolaceae family, which belongs to the Brassicales order. It is an excellent source of flavonoids, carotenoids, phenolic acids, vitamin C, and it is a plant that contains the ...
Ivana Vrca +4 more
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Bacterial Degradation of Benzyl Isothiocyanate [PDF]
Applied Microbiology, 1972 Bacteria that degrade benzyl isothiocyanate to benzylamine and hydrogen sulfide were isolated from papaya pulp homogenate by enrichment culture techniques. These organisms were identified as members of Enterobacter cloacae .
C S, Tang, K, Bhothipaksa, H A, Frank
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Antioxidants, 2021 Malignant melanoma is one of the most deadly types of solid cancers, a property mainly attributed to its highly aggressive metastatic form. On the other hand, different classes of isothiocyanates, a class of phytochemicals, present in cruciferous ...
Melina Mitsiogianni +7 more
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