Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Glutathione reductase (GR), an essential antioxidant enzyme against oxidative stress, has become an attractive drug target for the development of anticancer and antimalarial drugs.
Xia Li, Maowei Ni, Xiaoling Xu, Wei Chen
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Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells. [PDF]
PLoS ONE, 2012 Benzyl isothiocyanate (BITC), a constituent of edible cruciferous vegetables, inhibits growth of breast cancer cells but the mechanisms underlying growth inhibitory effect of BITC are not fully understood.
Dong Xiao +5 more
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, 2021 The metabolism of benzyl and phenyl glucosinolates by three phytopathogenic fungal species is investigated and established that A. brassicicola metabolized intact benzyl and phenyl glucosinolates and the corresponding desulfo derivatives.
Chintamani, Thapa +2 more
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, 2022 The title inorganic-organic hybrid material containing a mixed anion, [BzIQl]2[Zn(NCS)2Br2] (1) (BzIQl = benzyl isoquinolinium, NCS− = isothiocyanate), crystallizes with a benzyl isoquinolinium cation and half of a bis(bromo)-bis(isothiocyanate)zinc(II ...
Yi-Lin Xu (12280540) +8 more
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Quantitative and Qualitative Analysis of and Seeds by UPLC-DAD and UPLC-ESI-QTOF
Natural Product Communications, 2017 Eruca sativa and Brassica juncea belong to the Brassicaceae family and have been used traditionally for the treatment of cancer and various cardiovascular ailments.
Arti Sharma +5 more
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In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells [PDF]
Vojnosanitetski Pregled, 2016 Background/Aim. Numerous epidemiological studies have shown beneficial effects of cruciferous vegetables consumption in cancer chemoprevention.
Konić-Ristić Aleksandra +6 more
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Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity
Molecules, 2022 For decades, various plants have been studied as sources of biologically active compounds. Compounds with anticancer and antimicrobial properties are the most frequently desired.
Łukasz Janczewski
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Polarographic simultaneous determination of benzyl thiocyanate and benzyl isothiocyanate
BUNSEKI KAGAKU, 1973 有機チオシアネートおよびイソチオシアネート類としてベンジルチオシアネート(BTC)およびベンジルイソチオシアネート(BIT)を取り上げ,ポーラログラフ法により両者の同時定量を試みた.BTCおよびBITを含む試料液にn-ブチルアミンを添加し,BITを対応するチオウレア誘導体に変え,常法により直流ポーラログラムを記録し,チオウレア誘導体の酸化波とBTCの還元波より両者の分離定量を行なった.BTCおよびBITのそれぞれ1×10-3～1×10-4M範囲における検量線は直線性を示し,5×10-4Mにおける変動係数はBTCでは3.3%,BITでは2.2%であった.さらに本法をBTCの放射線分解物の分析に応用した.
SUGII, Atsushi +3 more
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Effects of intraspecific variation in white cabbage (brassica oleracea var. Capitata) on soil organisms [PDF]
, 2010 Contains fulltext : 84267.pdf (Publisher’s version ) (Closed access)20 ...
Dam, N.M., van +11 more
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Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent [PDF]
Mutagenesis, 1999 Benzyl isothiocyanate (BITC) is contained in cruciferous plants which are part of the human diet. Numerous reports indicate that BITC prevents chemically induced cancer in laboratory animals and it has been postulated that BITC might also be chemoprotective in humans.
F, Kassie +3 more
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