Results 41 to 50 of about 1,103 (154)
Background: Vernal keratoconjunctivitis is a chronic, recurrent, bilateral inflammatory disease of cornea and conjunctiva affecting young children. Various treatment modalities of VKC are topical mast cell stabilizers, anti-histaminics, corticosteroids ...
Ashish Chander +3 more
semanticscholar +1 more source
Effects of olopatadine hydrochloride, a histamine H1 receptor antagonist, on histamine‐induced skin responses were evaluated in 10 healthy subjects in comparison with placebo, fexofenadine hydrochloride, and bepotastine besilate. Olopatadine significantly suppressed histamine‐induced wheal, flare, and itch, starting 30 minutes after oral administration.
Takashi Hashimoto +7 more
wiley +1 more source
Background Empirical therapy with oral histamine-1 receptor antagonists (H1RAs) is often used for patients with suspected upper airway cough syndrome. No placebo-controlled trials with nonsedating H1RAs (nsH1RAs) have evaluated validated cough outcomes ...
Tae-Bum Kim +5 more
core +1 more source
Usefulness and Safety of Bepotastine Besilate for Pruritic Skin Disorders
ベシル酸ベポタスチンは鎮静効果が比較的弱く,即効性のある薬剤として各種そう痒性皮膚疾患に使用されている。今回,91例のそう痒性皮膚疾患に対してベシル酸ベポタスチンを投与し,その前後でVASスケールを用いてそう痒および眠気の推移について検討した。そう痒に関して投与前の平均VASスコアは60.6から投与1週間後では24.9と有意にスコアの低下がみられ,その効果は8週間投与観察期間中持続した。一方,眠気についてはベシル酸ベポタスチン内服後VASスコアの有意な上昇はみられなかった。また,投与前そう痒が強く,睡眠が障害され,投与前の眠気VASスコアが上昇していた症例では,ベシル酸ベポタスチン投与によるそう痒の改善から有意に眠気のVASスコアの改善がみられた ...
TAKAHASHI, Hidetoshi, IIZUKA, Hajime
openaire +2 more sources
Subhabrata Parida, Satya Narayan Mallik
semanticscholar +2 more sources
A comparative study to assess the efficacy and safety of bepotastine and cetirizine in allergic rhinitis [PDF]
Background: Pharmacotherapy is the mainstay of allergic rhinitis and many caregivers use over-the-counter antihistamines. Bepotastine is a novel oral second generation non-sedative antihistamine and an effective treatment option for allergic rhinitis ...
Mamatha, K. R. +2 more
core +1 more source
SIMULTANEOUS ESTIMATION OF BEPOTASTINE BESILATE AND BENZALKONIUM CHLORIDE IN OPHTHALMIC FORMULATION BY RP-HPLC METHOD [PDF]
Objective: Development and validation of stability indicating RP-HPLC method for the simultaneous determination of bepotastine besilate (Bepo B) and benzalkonium chloride (BKC) in an ophthalmic dosage form.Methods: A chromatographic separation of the ...
Gupta, Krishna R., Askarka, Sonali S.
core +1 more source
Immediate Clinical Effectiveness of Bepotastine Besilate for Patients with Urticaria
蕁麻疹患者25例を対象として,ベシル酸ベポタスチン錠(タリオン®錠)の即効性と有用性に関するアンケート調査を行なった。即効性(内服後痒みの抑制効果を自覚した時間)に関しては回答を得た20例で,全例が内服後90分以内に痒みの抑制効果を自覚していた(内服後30分以内が50%,内服後60分以内が89%)。また92%以上が何らかの有効性を自覚していた。効果の持続時間に関しては,回答を得た19例で,4時間が16%,8時間32%,12時間が47%という結果であった。眠気の副作用は33%に認められたが,84%の患者は再処方を希望したことから,本剤の高い有用性が示された。
KOHDA, Futoshi +2 more
openaire +1 more source
Double-Blind Placebo-Controlled Trial of Bepotastine Salicylate in Patients With Allergic Rhinitis
Objectives/hypothesis: To evaluate the efficacy and safety of a slow-release form of bepotastine salicylate (HL151, Belion CR) in patients with perennial allergic rhinitis (PAR).
김창훈
core +1 more source
Simultaneous spectrophotometric determination of losartan potassium, amlodipine besilate and hydrochlorothiazide in pharmaceuticals by chemometric methods [PDF]
U radu su opisane četiri spektrofotometrijske metode za istodobno određivanje losartan kalija, amlodipin besilata i hidroklorotiazida u sirovinama i farmaceutskim pripravcima.
Divya, O. +9 more
core +1 more source

