Results 61 to 70 of about 1,103 (154)

Stability Indicating Chromatographic Method For Estimation Of Bepotastine Besilate

, 2018
A Simple, rapid, stability indicating HPTLC method has been developed for estimation of bepotastine besilate. HPTLC separation was carried out on Merck TLC aluminium sheets precoated with silica gel 60F254 using mobile phase as chloroform : methanol. Bepotastine besilate gave sharp peak at RF 0.53 ±0.03 at 225nm.calibration curve was linear in range 5 ...
openaire   +2 more sources

Effectiveness of Second-Generation Antihistamine for the Treatment of MorningSymptoms Observed in Patients with Perennial Allergic Rhinitis: ComparisonStudy of Bepotastine Besilate versus Olopatadine Hydrochloride

, 2015
Objective: The aim of the present study was to examine circadian rhythm-based treatment strategies with the intension of improving the pharmacotherapy for morning symptoms with perennial allergic rhinitis.
Terumichi Fujikura, K. Okubo
semanticscholar   +1 more source

Pharmacokinetic Modeling of Bepotastine for Determination of Optimal Dosage Regimen in Pediatric Patients with Allergic Rhinitis or Urticaria

Bepotastine, a second-generation antihistamine for allergic rhinitis and urticaria, is widely used in all age groups but lacks appropriate dosing guidelines for pediatric patients, leading to off-label prescriptions. We conducted this study to propose an
Byung Hak Jin, Kyungsoo Park, Sukyong Yoon, Choon Ok Kim, Min Soo Park, Dongwoo Chae   +5 more
core   +1 more source

Synthesis, characterization and in vitro evaluation of novel enantiomerically-pure sulphonamide antimalarials

, 2015
Malaria parasites are currently gaining drug-resistance rapidly, across countries and continents. Hence, the discovery and development of novel chemical scaffolds, with superior antimalarial activity remain an important priority, for the developing world.
Shivananju, NanjundaSwamy, Mathai, Jessin, Rangappa, K.S., Bender, A., Anusha, S., Anusha, Sebastian, Shivananju, N., Babu Rajeev, C. P., Bender, Andreas, Fuchs, J. E., Rangappa, K. S., Sinha, Ameya, Chandramohanadas, Rajesh, Basappa, S., Mathai, J., Chandramohanadas, R., Ximei, H., Chu, T. T. T., Preiser, Peter Rainer, Preiser, P. R., Chu, T.T.T., Shivananju, N. S., Sinha, A., Fuchs, J.E., Babu Rajeev, C.P., Preiser, P.R., Basappa, Rangappa, Kanchugarakoppal S., Huang, Ximei, Fuchs, Julian E., Rajeev, C. P. B., Chu, Trang T. T.   +31 more
core   +1 more source

A Questionnaire-based Survey on the Clinical Efficacy of Bepotastine Besilate in the Treatment of Patients with Pruritic Skin Diseases

Nishi Nihon Hifuka, 2010
平成20年5月から12月にかけて，九州大学病院皮膚科と関連病院皮膚科に通院中の，そう痒性皮膚疾患を有する患者107例(平均年齢は52.1±19.0歳，男女比=45 : 62)を対象として，少なくとも1 週間のベシル酸べポスタチン投与後に，そう痒の改善と日中の眠気，夜間の睡眠，服用に適した錠剤の色と形状，満足度などについてアンケート調査を行った。日中のそう痒の改善は全体で88.6％，夜間のそう痒の改善は89.5％で，疾患別にみると蕁麻疹群(日中 : 94.3％，夜間 : 97.1％)は湿疹・皮膚炎群(日中 : 87.2％，夜間 : 89.4％)に比べて有意に改善していた ...
OMORI, Mutsumi, TAKEUCHI, Satoshi, TASHIRO, Akari, NAKAHARA, Takeshi, MITOMA, Chikage, TERAO, Hiroshi, URATA, Yasushi, YOSHIMURA, Eri, KUDO, Kyoko, YASUKAWA, Shinsuke, TSUJITA, Jun, KOKUBA, Hisashi, MASUNAGA, Kana, KUWAHARA, Kentaro, ICHIKAWA, Ryutaro, ITO, Eriko, TAKESHITA, Hiromichi, YASUKAWA, Fumiko, NISHIE, Atsuko, MOROI, Yoichi, FURUE, Masutaka   +20 more
openaire   +1 more source

Semisolid matrix-filled hard gelatin capsules for rapid dissolution of amlodipine besilate: Development and assessment

, 2013
The objective of the study was to prepare semisolid capsules (SSCs) of poorly water-soluble drug amlodipine besilate (AB) using a combination of technologies involving solid dispersion (SD) preparation and converting it into semisolid matrix filled in ...
Kamla Pathak, Vijay K Tyagi, Deshvir Singh   +2 more
core   +1 more source

Pharmacokinetic Characteristics of Bepotastine Besilate in Healthy Subjects [PDF]

Journal of Korean Society for Clinical Pharmacology and Therapeutics, 2007
Bo-Hyung Kim, Jae-Yong Chung, Jung-Ryul Kim, Kyoung Soo Lim, Hyeong-Seok Lim, Kyung-Sang Yu, In-Jin Jang, Sang-Goo Shin   +7 more
openaire   +1 more source

Atomic Pairwise Distribution Function Analysis of the Amorphous Phase Prepared by Different Manufacturing Routes

, 2012
Amlodipine besilate, a calcium channel antagonist, exists in several solid forms. Processing of anhydrate and dihydrate forms of this drug may lead to solid state changes, and is therefore the focus of this study.
Vishal Koradia, Koradia, Vishal, Savolainen, Marja, Marja Savolainen, Boetker, Johan P., Jukka Rantanen, Rantanen, Jukka, Johan P. Boetker, Thomas Rades, Rades, Thomas   +9 more
core   +1 more source

Clinical Study Concentrations of H1-Receptor Antagonist in the Human Nasal Mucosa

, 2009
Aims. To measure blood and tissue concentrations of the H1-receptor antagonist, bepotastine besilate (BB). Methods. Participants included 14 men and six women, whose age ranged from 13 to 76 years, with chronic rhinosinusitis, who underwent endoscopic ...
Haruo Takahashi, Kenji Takasaki, Kaori Enatsu, Hidetaka Kumagami   +3 more
core  

Zebra Body Not Caused by Fabry Disease. [PDF]

Intern Med, 2023
Fukunaga S, Egawa M, Ito T, Tanabe K.
europepmc   +1 more source