Results 151 to 160 of about 26,756 (250)
Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley +1 more source
Natural Products as Modulators of ABC Transporters in Breast Cancer
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source
Basic Notions and Innovations in Electrochemical Advanced Oxidation Processes for Water Treatment
Electrochemical advanced oxidation processes effectively degrade persistent organic pollutants, turning polluted water into a clean resource. Through the use of reactive species, hybrid systems, and computational modeling these approaches optimize treatment and open the door to innovative, sustainable next‐generation water purification technologies ...
Fida Tanos +11 more
wiley +1 more source
ABSTRACT Plant‐based antioxidants are widely incorporated into foods to retard oxidative deterioration and to deliver health‐related benefits. Yet, their in‐product and in vivo performance frequently diverges from predictions based on solution‐phase chemical assays, because matrix interactions, processing history, and host metabolism reshape both ...
Márcio Vargas‐Ramella +6 more
wiley +1 more source
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge +8 more
wiley +1 more source
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song +14 more
wiley +1 more source
Discovery of pseudobaptigenin synthase in fungal‐infected Trifolium pratense roots
Significance Statement The discovery of pseudobaptigenin synthase in red clover (CYP76F319), catalyzing the formation of a methylenedioxy bridge to convert calycosin to pseudobaptigenin. The integration of metabolomic and transcriptomic datasets to describe the defense response in red clover roots to hemibiotrophic and necrotrophic fungi.
Lee Marie Raytek +3 more
wiley +1 more source
BIOSYNTHESIS OF HYDRASTINE AND BERBERINE [PDF]
The biosynthesis of hydrastine and of berberine was investigated by feeding radioactive tyrosine and dopamine to Hydrastis canadensis L. It was shown that both hydrastine and berberine are specifically derived from two molecules of tyrosine, but that
James, Richard Gear
core
Neuroprotective mechanisms of nutraceutical berberine: Preclinical evidence and future perspectives. [PDF]
Obafemi BA +4 more
europepmc +1 more source
Enhanced antimicrobial activity, mechanical and dielectric properties of styrene butadiene rubber vulcanizates designed for protection products. [PDF]
El-Nashar DE +8 more
europepmc +1 more source

